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DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

KLK3 recombinant protein :: (Rhesus macaque) Prostate-specific antigen (KLK3) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS955480 KLK3 recombinant protein
Unit / Price
1 mg (E-Coli)  /  $1,460 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,920 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

(Rhesus macaque) Prostate-specific antigen (KLK3), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Macaca mulatta (Rhesus macaque) Prostate-specific antigen (KLK3)

 Product Synonym Names    Recombinant (Rhesus macaque) Prostate-specific antigen (KLK3); Prostate-specific antigen; PSA EC= 3.4.21.77; Kallikrein-3 Semenogelase
 Product Gene Name   

KLK3 recombinant protein

[Similar Products]
 Product Synonym Gene Name    KLK3; APS [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    25-261
 Sequence    IVGGWECEKH SQPWQVLVAS RGRAVCGGVL VHPQWVLTAA HCIRSNSVIL LGRHNPYYPE DTGQVFQVSH SFPHPLYNMS LLKNRYLGPG DDSSHDLMLL RLSEPAEITD AVQVLDLPTW EPELGTTCYA SGWGSIEPEE HLTPKKLQCV DLHIISNDVC AQVHSQKVTK FMLCAGSWMG GKSTCSGDSG GPLVCDGVLQ GITSWGSQPC ALPRRPSLYT KVVRYRKWIQ DTIMANP
 Chromosome Location    Chromosome: 19; NC_007876.1 (57061486..57067329). Location: chromosome: 19
 3D Structure    ModBase 3D Structure for P33619
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Macaca mulatta (Rhesus macaque)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of KLK3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for KLK3. It may not necessarily be applicable to this product.
 NCBI GI #    112421199
 NCBI GeneID    719444
 NCBI Accession #    NP_001036241.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001042776.1 [Other Products]
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 UniProt Primary Accession #    P33619 [Other Products]
 UniProt Related Accession #    P33619 [Other Products]
 Molecular Weight    28,816 Da [Similar Products]
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 NCBI Official Full Name    prostate-specific antigen
 NCBI Official Symbol    KLK3 [Similar Products]
 NCBI Official Synonym Symbols   
PSA
[Similar Products]
 NCBI Protein Information    prostate-specific antigen; kallikrein-3; semenogelase; prostate specific antigen; kallikrein-related peptidase 3
 UniProt Protein Name    Prostate-specific antigen
 UniProt Synonym Protein Names   
Kallikrein-3; Semenogelase
 Protein Family    Glandular kallikrein
 UniProt Gene Name    KLK3 [Similar Products]
 UniProt Synonym Gene Names    APS; PSA [Similar Products]
 UniProt Entry Name    KLK3_MACMU
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 UniProt Comments for KLK3    Function: Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum

By similarity.

Catalytic activity: Preferential cleavage: -Tyr-|-Xaa-.

Enzyme regulation: Inhibited by SERPINA5. Activity is strongly inhibited by Zn2+, 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins, which are avid zinc binders

By similarity.

Subunit structure: Forms heterodimer with SERPINA5

By similarity.

Subcellular location: Secreted

By similarity.

Sequence similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.Contains 1 peptidase S1 domain.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with KLK3 recombinant proteinDiseases associated with KLK3 recombinant protein
 Products by Pathway  Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Prostate Cancer Pathway antibodies  Prostate Cancer Pathway Diagram
 Prostate Cancer Pathway antibodies  Prostate Cancer Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >71 publications with KLK3 and Neoplasms
 Prostatic Neoplasms Antibodies  >54 publications with KLK3 and Prostatic Neoplasms
 Carcinoma Antibodies  >18 publications with KLK3 and Carcinoma
 Breast Neoplasms Antibodies  >12 publications with KLK3 and Breast Neoplasms
 Adenocarcinoma Antibodies  >11 publications with KLK3 and Adenocarcinoma
 Hyperplasia Antibodies  >7 publications with KLK3 and Hyperplasia
 Prostatic Hyperplasia Antibodies  >7 publications with KLK3 and Prostatic Hyperplasia
 Kidney Diseases Antibodies  >6 publications with KLK3 and Kidney Diseases
 Disease Progression Antibodies  >6 publications with KLK3 and Disease Progression
 Neoplasms, Experimental Antibodies  >5 publications with KLK3 and Neoplasms, Experimental
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