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SNAP25 recombinant protein :: (Rhesus macaque) Synaptosomal-associated protein 25 (SNAP25) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS961856 SNAP25 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $605 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $755 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $810 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $895 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $905 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,015 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,140 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,140 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,145 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,260 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,645 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,740 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,740 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,195 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

(Rhesus macaque) Synaptosomal-associated protein 25 (SNAP25), Recombinant Protein

 Also Known As   

Recombinant Macaca mulatta (Rhesus macaque) Synaptosomal-associated protein 25 (SNAP25)

 Product Synonym Names    Recombinant (Rhesus macaque) Synaptosomal-associated protein 25 (SNAP25); Synaptosomal-associated protein 25; SNAP-25; Synaptosomal-associated 25 kDa protein
 Product Gene Name   

SNAP25 recombinant protein

[Similar Products]
 Product Synonym Gene Name    SNAP25 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-206aa; Full length protein
 Sequence    MAEDADMRNE LEEMQRRADQ LADESLESTR RMLQLVEESK DAGIRTLVML DEQGEQLERI EEGMDQINKD MKEAEKNLTD LGKFCGLCVC PCNKLKSSDA YKKAWGNNQD GVVASQPARV VDEREQMAIS GGFIRRVTND ARENEMDENL EQVSGIIGNL RHMALDMGNE IDTQNRQIDR IMEKADSNKT RIDEANQRAT KMLGSG
 Chromosome Location    Chromosome: 10; NC_007867.1 (43494269..43580338). Location: chromosome: 10
 3D Structure    ModBase 3D Structure for P60877
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Macaca mulatta (Rhesus macaque)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of SNAP25 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for SNAP25 recombinant protein

   Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and This protein contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
NCBI/Uniprot data below describe general gene information for SNAP25. It may not necessarily be applicable to this product.
 NCBI GI #    74136289
 NCBI GeneID    574204
 NCBI Accession #    NP_001028036.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001032864.1 [Other Products]
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 UniProt Primary Accession #    P60877 [Other Products]
 UniProt Secondary Accession #    P13795; P36974; P70557; P70558; Q8IXK3; Q96FM2; Q9BR45 [Other Products]
 UniProt Related Accession #    P60877 [Other Products]
 Molecular Weight    23,315 Da [Similar Products]
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 NCBI Official Full Name    synaptosomal-associated protein 25
 NCBI Official Symbol    SNAP25 [Similar Products]
 NCBI Official Synonym Symbols   
SNAP-25
[Similar Products]
 NCBI Protein Information    synaptosomal-associated protein 25; synaptosomal-associated 25 kDa protein; synaptosomal-associated protein 25 isoform SNAP25B
 UniProt Protein Name    Synaptosomal-associated protein 25
 UniProt Synonym Protein Names   
Synaptosomal-associated 25 kDa protein
 Protein Family    Synaptosomal-associated protein
 UniProt Gene Name    SNAP25 [Similar Products]
 UniProt Synonym Gene Names    SNAP-25 [Similar Products]
 UniProt Entry Name    SNP25_MACMU
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 UniProt Comments for SNAP25    Function: t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF

By similarity.

Subunit structure: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds CPLX1. Interacts with CENPF, TRIM9, RIMS1, SNAPIN, OTOF and HGS. Binds STXBP6. Found in a ternary complex with STX1A and VAMP8. Found in a complex containing SYT1, SV2B and syntaxin-1. Associates with the BLOC-1 complex. Interacts with BLOC1S6

By similarity. Interacts with EQTN

By similarity.

Subcellular location: Cytoplasm › perinuclear region

By similarity. Cell membrane; Lipid-anchor

By similarity. Cell junction › synapse › synaptosome

By similarity. Note: Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region

By similarity.

Post-translational modification: Palmitoylated. Cys-85 appears to be the main site, and palmitoylation is required for membrane association

By similarity.

Sequence similarities: Belongs to the SNAP-25 family.Contains 2 t-SNARE coiled-coil homology domains.
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 Research Articles on SNAP25    1. These data demonstrate a differential ability of SNAP-25 homlog to support neuronal function.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with SNAP25 recombinant proteinDiseases associated with SNAP25 recombinant protein
 Products by Pathway  Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >108 publications with SNAP25 and Mental Disorders
 Nervous System Diseases Antibodies  >96 publications with SNAP25 and Nervous System Diseases
 Brain Diseases Antibodies  >65 publications with SNAP25 and Brain Diseases
 Schizophrenia Antibodies  >32 publications with SNAP25 and Schizophrenia
 Drug Toxicity Antibodies  >32 publications with SNAP25 and Drug Toxicity
 Dementia Antibodies  >30 publications with SNAP25 and Dementia
 Paralysis Antibodies  >19 publications with SNAP25 and Paralysis
 Cognition Disorders Antibodies  >14 publications with SNAP25 and Cognition Disorders
 Pain Antibodies  >12 publications with SNAP25 and Pain
 Memory Disorders Antibodies  >11 publications with SNAP25 and Memory Disorders
Organs/Tissues associated with SNAP25 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >382 publications with SNAP25 and Brain
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