P29451.2
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
11,737 Da
NCBI Official Full Name
Thioredoxin
NCBI Protein Information
thioredoxin
UniProt Protein Name
Thioredoxin
UniProt Synonym Gene Names
UniProt Comments for TXN
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity ().
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Products associated with TXN recombinant protein
Pathways associated with TXN recombinant protein
Organs/Tissues associated with TXN recombinant protein
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