P79189.1
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UniProt Primary Accession #
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NCBI Official Full Name
fMet-Leu-Phe receptor
UniProt Protein Name
fMet-Leu-Phe receptor
UniProt Synonym Protein Names
N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
UniProt Synonym Gene Names
UniProt Entry Name
FPR1_MACMU
UniProt Comments for FPR1
Function: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Post-translational modification: Phosphorylated; which is necessary for desensitization
By similarity.
Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
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Products associated with FPR1 recombinant protein
Pathways associated with FPR1 recombinant protein
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