NP_115961.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ribonuclease 7
NCBI Official Synonym Full Names
ribonuclease, RNase A family, 7
NCBI Protein Information
ribonuclease 7; RNase 7; SAP-2; skin-derived antimicrobial protein 2
UniProt Protein Name
Ribonuclease 7
UniProt Synonym Protein Names
Skin-derived antimicrobial protein 2; SAP-2
UniProt Synonym Gene Names
UniProt Entry Name
RNAS7_HUMAN
NCBI Summary for RNASE7
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein has broad-spectrum antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
UniProt Comments for RNASE7
RNASE7: Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Belongs to the pancreatic ribonuclease family.
Protein type: Ribonuclease; Secreted; EC 3.1.27.-; RNA-binding; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 14q11.2
Cellular Component: extracellular region
Molecular Function: peptidoglycan binding; nucleic acid binding; lipopolysaccharide binding; endonuclease activity; ribonuclease activity
Biological Process: defense response to Gram-positive bacterium; response to bacterium; antibacterial humoral response; innate immune response; membrane disruption in another organism; defense response to Gram-negative bacterium
Research Articles on RNASE7
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Products associated with RNASE7 recombinant protein
Diseases associated with RNASE7 recombinant protein
Organs/Tissues associated with RNASE7 recombinant protein
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