NP_001008290.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
28,752 Da
NCBI Official Full Name
ribosome maturation protein SBDS
NCBI Official Synonym Full Names
SBDS, ribosome maturation factor
NCBI Protein Information
ribosome maturation protein SBDS
UniProt Protein Name
Ribosome maturation protein SBDS
UniProt Synonym Protein Names
Shwachman-Bodian-Diamond syndrome protein homolog
UniProt Comments for Sbds
Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation ().
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Products associated with Sbds recombinant protein
Pathways associated with Sbds recombinant protein
Diseases associated with Sbds recombinant protein
Organs/Tissues associated with Sbds recombinant protein
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