NP_005611.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,740 Da
NCBI Official Full Name
protein S100-A11
NCBI Official Synonym Full Names
S100 calcium binding protein A11
NCBI Protein Information
protein S100-A11; MLN 70; S100 calcium-binding protein A11 (calgizzarin); epididymis secretory protein Li 43; metastatic lymph node gene 70 protein; protein S100-C
UniProt Protein Name
Protein S100-A11
UniProt Synonym Protein Names
Calgizzarin; Metastatic lymph node gene 70 protein; MLN 70; Protein S100-C; S100 calcium-binding protein A11Protein S100-A11, N-terminally processed
UniProt Synonym Gene Names
UniProt Entry Name
S10AB_HUMAN
NCBI Summary for S100A11
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008]
UniProt Comments for S100A11
S100A11: a calcium-binding regulatory protein of the S-100 family. Interacts with the N-termini of annexins A1. May regulate fusion processes such as endo- and exocytosis. Increases in the early stage of pancreatic carcinogenesis and decreases during subsequent progression to cancer. Increased expression in anaplastic large cell lymphoma.
Protein type: DNA replication; Cell cycle regulation; Calcium-binding
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: nucleoplasm; ruffle; extracellular space; cytoplasm; nucleus
Molecular Function: protein binding; protein homodimerization activity; calcium ion binding; calcium-dependent protein binding
Biological Process: negative regulation of cell proliferation; negative regulation of DNA replication; signal transduction
Research Articles on S100A11
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Products associated with S100A11 recombinant protein
Diseases associated with S100A11 recombinant protein
Organs/Tissues associated with S100A11 recombinant protein
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