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S100P recombinant protein :: S100 Calcium Binding Protein P Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS144050 S100P recombinant protein
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.025 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $2,235 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

S100 Calcium Binding Protein P (S100P), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human S100 Calcium Binding Protein P, His Tag

 Product Synonym Names    Protein S100-E, S100E, Migration-Inducing Gene 9, MIG9
 Product Gene Name   

S100P recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHH HHH SSGLVPRGSH MTELETAMGM IIDVFSRYSG SEGSTQTLTK GELKVLMEKE LPGFLQSGKD KDAVDKLLKD LDANGDAQVD FSEFIVFVAA ITSACHKYFE KAGLK
 OMIM    600614
 3D Structure    ModBase 3D Structure for P25815
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 Purity/Purification    Greater than 90.0% as determined by SDS-PAGE.
 Form/Format    S100P Human solution containing 20mM Trsi HCL pH-8, 1mM DTT, 0.05M NaCl & 20% glycerol.
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 Source    E.coli
 Physical Appearance    Sterile filtered colorless solution
    
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 Preparation and Storage    Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
 Other Notes    Small volumes of S100P recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for S100P recombinant protein

   Description: S100P Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 115 amino acids (1-95a.a.) and having a molecular mass of 12.6 kDa. S100P protein is fused to a 20 amino acid His tag at N-terminus and is purified by standard chromatography.

Introduction: S100P is a Ca2+ binding protein that is part of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are found in the cytoplasm and/or nucleus of a large range of cells, and participates in the regulation of a number of cellular function such as cell cycle progression and differentiation. S100P participates in numerous biological functions but the exact functions or mechanism of its action is still mostly unknown. Once S100P binds calcium ions it goes through a conformational change that results in an exposure of a hydrophobic surface which permits the interaction with specific target proteins.
 Product Categories/Family for S100P recombinant protein    RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Calcium Binding Protein
NCBI/Uniprot data below describe general gene information for S100P. It may not necessarily be applicable to this product.
 NCBI GI #    5174663
 NCBI GeneID    6286
 NCBI Accession #    NP_005971.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005980.2 [Other Products]
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 UniProt Primary Accession #    P25815 [Other Products]
 UniProt Secondary Accession #    Q5J7W2 [Other Products]
 UniProt Related Accession #    P25815 [Other Products]
 Molecular Weight    10,400 Da
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 NCBI Official Full Name    protein S100-P
 NCBI Official Synonym Full Names    S100 calcium binding protein P
 NCBI Official Symbol    S100P [Similar Products]
 NCBI Official Synonym Symbols   
MIG9
[Similar Products]
 NCBI Protein Information    protein S100-P; S100 calcium-binding protein P; migration-inducing gene 9 protein; protein S100-E
 UniProt Protein Name    Protein S100-P
 UniProt Synonym Protein Names   
Migration-inducing gene 9 protein; MIG9; Protein S100-E; S100 calcium-binding protein P
 Protein Family    Protein
 UniProt Gene Name    S100P [Similar Products]
 UniProt Synonym Gene Names    S100E; MIG9 [Similar Products]
 UniProt Entry Name    S100P_HUMAN
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 NCBI Summary for S100P    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008]
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 UniProt Comments for S100P    S100P: Homodimer. Interacts with S100PBP and S100Z. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. Belongs to the S-100 family.

Chromosomal Location of Human Ortholog: 4p16

Cellular Component: microvillus membrane; cytoplasm; nucleus

Molecular Function: RAGE receptor binding; protein binding; magnesium ion binding; calcium ion binding; calcium-dependent protein binding

Biological Process: response to organic substance; endothelial cell migration
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 Research Articles on S100P    1. S100P may promote endometrial tumor cell proliferation by increasing nuclear translocation of beta-catenin.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with S100P recombinant proteinPathways associated with S100P recombinant protein
 Reference Product  PubMed Publications
 S100A4 recombinant protein  >30 publications with S100P and S100A4
 S100A2 recombinant protein  >20 publications with S100P and S100A2
 RAGE recombinant protein  >20 publications with S100P and RAGE
 S100A1 recombinant protein  >16 publications with S100P and S100A1
 S100PBP recombinant protein  >7 publications with S100P and S100PBP
 S100A3 recombinant protein  >3 publications with S100P and S100A3
 MYH9 recombinant protein  >1 publications with S100P and MYH9
 Products by Pathway  Pathway Diagram
 Gastric Cancer Network 1 Pathway antibodies  Gastric Cancer Network 1 Pathway Diagram
Diseases associated with S100P recombinant proteinOrgans/Tissues associated with S100P recombinant protein
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >101 publications with S100P and Carcinoma
 Adenocarcinoma Antibodies  >77 publications with S100P and Adenocarcinoma
 Neoplasm Metastasis Antibodies  >45 publications with S100P and Neoplasm Metastasis
 Pancreatic Neoplasms Antibodies  >42 publications with S100P and Pancreatic Neoplasms
 Breast Neoplasms Antibodies  >29 publications with S100P and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >16 publications with S100P and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >15 publications with S100P and Lung Neoplasms
 Carcinoma, Squamous Cell Antibodies  >15 publications with S100P and Carcinoma, Squamous Cell
 Prostatic Neoplasms Antibodies  >14 publications with S100P and Prostatic Neoplasms
 Cell Transformation, Neoplastic Antibodies  >14 publications with S100P and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >26 publications with S100P and Prostate
 Pancreas Antibodies  >25 publications with S100P and Pancreas
 Liver Antibodies  >21 publications with S100P and Liver
 Lung Antibodies  >20 publications with S100P and Lung
 Blood Antibodies  >15 publications with S100P and Blood
 Lymph Node Antibodies  >13 publications with S100P and Lymph Node
 Stomach Antibodies  >13 publications with S100P and Stomach
 Bladder Antibodies  >11 publications with S100P and Bladder
 Placenta Antibodies  >10 publications with S100P and Placenta
 Uterus Antibodies  >7 publications with S100P and Uterus
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