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STX12 recombinant protein

Scan QR to view Datasheet Catalog #    MBS204335
Unit / Price
0.02 mg  /  $310 +1 FREE 8GB USB
0.1 mg  /  $720 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

STX12, Recombinant Protein

 Also Known As   

STX12, 1-248aa, Human, His tag, E Coli

 Product Synonym Names    Syntaxin 12; STX13; STX14
 Product Gene Name   

STX12 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AF123769 mRNA
 3D Structure    ModBase 3D Structure for Q86Y82
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 Host    E Coli
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 Purity/Purification    > 90% by SDS-PAGE
 Form/Format    Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 1mM DTT
 Concentration    0.5 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag Information    His-tag
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of STX12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for STX12 recombinant protein

   Syntaxin 12, also known as, belongs to the syntaxin family. Syntaxin family is cellular receptors for transport vesicles which participate in exocytosis in neutrophils. STX12 regulates protein transport between late endosomes and the trans-Golgi network and interacts with ABC1 (ATP-binding cassette transporter A1), a protein that facilitates cellular release of choline-phospholipids and cholesterol to apoA-I (apolipoprotein A-I). Recombinant human STX12 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
 Product Categories/Family for STX12 recombinant protein    Transportation
 Applications Tested/Suitable for STX12 recombinant protein   


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 SDS-Page of STX12 recombinant protein    STX12 recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for STX12. It may not necessarily be applicable to this product.
 NCBI GI #    28933465
 NCBI GeneID    23673
 NCBI Accession #    NP_803173 [Other Products]
 NCBI GenBank Nucleotide #    NM_177424.2 [Other Products]
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 UniProt Primary Accession #    Q86Y82 [Other Products]
 UniProt Secondary Accession #    O95564; B1AJQ7 [Other Products]
 UniProt Related Accession #    Q86Y82 [Other Products]
 Molecular Weight    31.0 kDa (272aa), confirmed by MALDI-TOF
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 NCBI Official Full Name    syntaxin-12
 NCBI Official Synonym Full Names    syntaxin 12
 NCBI Official Symbol    STX12 [Similar Products]
 NCBI Official Synonym Symbols   
STX13; STX14
[Similar Products]
 NCBI Protein Information    syntaxin-12
 UniProt Protein Name    Syntaxin-12
 Protein Family    Syntaxin
 UniProt Gene Name    STX12 [Similar Products]
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 UniProt Comments for STX12    SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting ().
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Product References and Citations for STX12 recombinant protein

   Tang B L., et al. (1998) J Biol Chem. 273:6944-6950.; Prekeris R., et al. (1998) J Cell Biol. 143: 957-971.
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 Research Articles on STX12    1. Data indicate that knockdown of syntaxin 13 (syx13) further increased the cellular toxicity caused by mutant CHMP2B (CHMP2BIntron5) expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with STX12 recombinant proteinPathways associated with STX12 recombinant protein
 Reference Product  PubMed Publications
 VAMP7 recombinant protein  >2 publications with STX12 and VAMP7
 VTI1A recombinant protein  >1 publications with STX12 and VTI1A
 SNAP25 recombinant protein  >1 publications with STX12 and SNAP25
 SNAP23 recombinant protein  >1 publications with STX12 and SNAP23
 Products by Pathway  Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
Diseases associated with STX12 recombinant proteinOrgans/Tissues associated with STX12 recombinant protein
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >2 publications with STX12 and Brain Diseases
 Nervous System Diseases Antibodies  >1 publications with STX12 and Nervous System Diseases
 Fibrosis Antibodies  >1 publications with STX12 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with STX12 and Brain
 Muscle Antibodies  >1 publications with STX12 and Muscle
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