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SCTR recombinant protein :: Secretin receptor (SCTR) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS947954 SCTR recombinant protein
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Secretin receptor (SCTR), Recombinant Protein

 Also Known As   

Recombinant Human Secretin receptor (SCTR)

 Product Synonym Names    Recombinant Secretin receptor (SCTR); Secretin receptor; SCT-R
 Product Gene Name   

SCTR recombinant protein

[Similar Products]
 Product Synonym Gene Name    SCTR [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    23-440
 Sequence    HSTGALPRLC DVLQVLWEEQ DQCLQELSRE QTGDLGTEQP VPGCEGMWDN ISCWPSSVPG RMVEVECPRF LRMLTSRNGS LFRNCTQDGW SETFPRPNLA CGVNVNDSSN EKRHSYLLKL KVMYTVGYSS SLVMLLVALG ILCAFRRLHC TRNYIHMHLF VSFILRALSN FIKDAVLFSS DDVTYCDAHR AGCKLVMVLF QYCIMANYSW LLVEGLYLHT LLAISFFSER KYLQGFVAFG WGSPAIFVAL WAIARHFLED VGCWDINANA SIWWIIRGPV ILSILINFIL FINILRILMR KLRTQETRGN EVSHYKRLAR STLLLIPLFG IHYIVFAFSP EDAMEIQLFF ELALGSFQGL VVAVLYCFLN GEVQLEVQKK WQQWHLREFP LHPVASFSNS TKASHLEQSQ GTCRTSII
 Chromosome Location    Chromosome: 2; NC_000002.11 (120197419..120282028, complement). Location: 2q14.1
 OMIM    182098
 3D Structure    ModBase 3D Structure for P47872
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of SCTR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for SCTR. It may not necessarily be applicable to this product.
 NCBI GI #    114205383
 NCBI GeneID    6344
 NCBI Accession #    NP_002971.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002980.2 [Other Products]
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 UniProt Primary Accession #    P47872 [Other Products]
 UniProt Secondary Accession #    Q12961; Q13213; Q53T00 [Other Products]
 UniProt Related Accession #    P47872 [Other Products]
 Molecular Weight    50,207 Da [Similar Products]
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 NCBI Official Full Name    secretin receptor
 NCBI Official Synonym Full Names    secretin receptor
 NCBI Official Symbol    SCTR [Similar Products]
 NCBI Official Synonym Symbols   
SR
[Similar Products]
 NCBI Protein Information    secretin receptor; pancreatic secretin receptor
 UniProt Protein Name    Secretin receptor
 Protein Family    Secretin receptor
 UniProt Gene Name    SCTR [Similar Products]
 UniProt Synonym Gene Names    SCT-R [Similar Products]
 UniProt Entry Name    SCTR_HUMAN
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 NCBI Summary for SCTR    The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. [provided by RefSeq, Jul 2008]
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 UniProt Comments for SCTR    SCTR: This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q14.1

Cellular Component: integral to plasma membrane; cytoplasmic microtubule; plasma membrane

Molecular Function: secretin receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; digestion; excretion
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 Research Articles on SCTR    1. binding and activity of a series of 11 truncated and lactam-constrained secretin(5-27) analogues at the prototypic member of this family, the secretin receptor
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SCTR recombinant proteinPathways associated with SCTR recombinant protein
 Reference Product  PubMed Publications
 SCT recombinant protein  >5 publications with SCTR and SCT
 Products by Pathway  Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Glucagon-type Ligand Receptors Pathway antibodies  Glucagon-type Ligand Receptors Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with SCTR recombinant proteinOrgans/Tissues associated with SCTR recombinant protein
 Disease Name  Pubmed Publications
 Genital Diseases, Male Antibodies  >2 publications with SCTR and Genital Diseases, Male
 Cholangiocarcinoma Antibodies  >1 publications with SCTR and Cholangiocarcinoma
 Prostatic Diseases Antibodies  >1 publications with SCTR and Prostatic Diseases
 Cholestasis Antibodies  >1 publications with SCTR and Cholestasis
 Pancreatic Neoplasms Antibodies  >1 publications with SCTR and Pancreatic Neoplasms
 Cell Transformation, Neoplastic Antibodies  >1 publications with SCTR and Cell Transformation, Neoplastic
 Adenoma Antibodies  >1 publications with SCTR and Adenoma
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with SCTR and Brain
 Pancreas Antibodies  >3 publications with SCTR and Pancreas
 Intestine Antibodies  >1 publications with SCTR and Intestine
 Kidney Antibodies  >1 publications with SCTR and Kidney
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