NP_002999.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
64.9 kDa
NCBI Official Full Name
semenogelin-2
NCBI Official Synonym Full Names
semenogelin 2
NCBI Official Synonym Symbols
NCBI Protein Information
semenogelin-2
UniProt Protein Name
Semenogelin-2
UniProt Synonym Protein Names
Semenogelin II; SGII
UniProt Synonym Gene Names
NCBI Summary for SEMG2
The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. An antibacterial activity has been found for a antimicrobial peptide isolated from this protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. [provided by RefSeq, Jan 2015]
UniProt Comments for SEMG2
Participates in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions and ejaculated spermatozoa.
Research Articles on SEMG2
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Products associated with SEMG2 recombinant protein
Organs/Tissues associated with SEMG2 recombinant protein
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