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Spink3 recombinant protein :: Serine protease inhibitor Kazal-type 3 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1031087
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.01 mg (Yeast)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.1 mg (Yeast)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $460 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $750 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $785 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $990 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,025 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,180 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,440 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,570 +1 FREE 8GB USB
1 mg (Baculovirus)  /  $1,935 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Serine protease inhibitor Kazal-type 3 (Spink3), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Serine protease inhibitor Kazal-type 3

 Product Synonym Names    P12; Prostatic secretory glycoprotein
 Product Gene Name   

Spink3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    24-80aa; Full Length
 Sequence    AKVTGKEASC HDAVAGCPRI YDPVCGTDGI TYANECVLCF ENRKRIEPVL IRKGGPC
 3D Structure    ModBase 3D Structure for P09036
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Spink3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Spink3 recombinant protein

   Serine protease inhibitor which exhibits anti-trypsin activity. Inhibits the uptake of calcium by spermatozoa.
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 SDS-PAGE of Spink3 recombinant protein    Spink3 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Spink3. It may not necessarily be applicable to this product.
 NCBI GI #    6678105
 NCBI GeneID    20730
 NCBI Accession #    NP_033284.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_009258.5 [Other Products]
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 UniProt Primary Accession #    P09036 [Other Products]
 UniProt Secondary Accession #    Q5M9M3 [Other Products]
 UniProt Related Accession #    P09036 [Other Products]
 Molecular Weight    33.5kD
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 NCBI Official Full Name    serine protease inhibitor Kazal-type 1
 NCBI Official Synonym Full Names    serine peptidase inhibitor, Kazal type 1
 NCBI Official Symbol    Spink1 [Similar Products]
 NCBI Official Synonym Symbols   
p12; Spink3
[Similar Products]
 NCBI Protein Information    serine protease inhibitor Kazal-type 1
 UniProt Protein Name    Serine protease inhibitor Kazal-type 1
 UniProt Synonym Protein Names   
P12
 UniProt Gene Name    Spink1 [Similar Products]
 UniProt Entry Name    ISK1_MOUSE
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 UniProt Comments for Spink3    Spink3: Serine protease inhibitor which exhibits anti-trypsin activity. Inhibits the uptake of calcium by spermatozoa. By androgens in adult male sex accessory glands but expressed constitutively in pancreas

Protein type: Inhibitor

Cellular Component: acrosome; extracellular region; extracellular space

Molecular Function: protease inhibitor activity; serine-type endopeptidase inhibitor activity

Biological Process: negative regulation of peptidase activity; negative regulation of peptidyl-tyrosine phosphorylation; regulation of acrosome reaction
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Product References and Citations for Spink3 recombinant protein

   A secretory protease inhibitor requires androgens for its expression in male sex accessory tissues but is expressed constitutively in pancreas.Mills J.S., Needham M., Parker M.G.EMBO J. 6:3711-3717(1987) Purification and characterization of a trypsin inhibitor from mouse seminal vesicle secretion.Lai M.-L., Chen S.-W., Chen Y.-H.Arch. Biochem. Biophys. 290:265-271(1991) Developmental profile of a caltrin-like protease inhibitor, P12, in mouse seminal vesicle and characterization of its binding sites on sperm surface.Chen L.-Y., Lin Y.-H., Lai M.-L., Chen Y.-H.Biol. Reprod. 59:1498-1505(1998)
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 Research Articles on Spink3    1. It is a trypsin-specific inhibitor in the pancreas.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Spink3 recombinant proteinDiseases associated with Spink3 recombinant protein
 Reference Product  PubMed Publications
 Prss2 recombinant protein  >38 publications with Spink3 and Prss2
 Ctrc recombinant protein  >31 publications with Spink3 and Ctrc
 Egfr recombinant protein  >14 publications with Spink3 and Egfr
 Disease Name  Pubmed Publications
 Pancreatitis Antibodies  >393 publications with Spink3 and Pancreatitis
 Pancreatitis, Chronic Antibodies  >289 publications with Spink3 and Pancreatitis, Chronic
 Pancreatic Neoplasms Antibodies  >170 publications with Spink3 and Pancreatic Neoplasms
 Fibrosis Antibodies  >162 publications with Spink3 and Fibrosis
 Hereditary pancreatitis Antibodies  >66 publications with Spink3 and Hereditary pancreatitis
 Inflammation Antibodies  >42 publications with Spink3 and Inflammation
 Liver Diseases Antibodies  >25 publications with Spink3 and Liver Diseases
 Immune System Diseases Antibodies  >21 publications with Spink3 and Immune System Diseases
 Kidney Diseases Antibodies  >19 publications with Spink3 and Kidney Diseases
 Liver Neoplasms Antibodies  >19 publications with Spink3 and Liver Neoplasms
Organs/Tissues associated with Spink3 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >239 publications with Spink3 and Pancreas
 Prostate Antibodies  >62 publications with Spink3 and Prostate
 Intestine Antibodies  >60 publications with Spink3 and Intestine
 Kidney Antibodies  >39 publications with Spink3 and Kidney
 Bladder Antibodies  >18 publications with Spink3 and Bladder
 Embryonic Tissue Antibodies  >6 publications with Spink3 and Embryonic Tissue
 Uterus Antibodies  >3 publications with Spink3 and Uterus
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