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SAK recombinant protein :: Serine/threonine-protein kinase PLK4 (SAK) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1120458 SAK recombinant protein
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Serine/threonine-protein kinase PLK4 (SAK), Recombinant Protein

 Also Known As   

Recombinant Drosophila melanogaster Serine/threonine-protein kinase PLK4 (SAK), partial

 Product Gene Name   

SAK recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for O97143
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Drosophila melanogaster (Fruit fly)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of SAK recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for SAK. It may not necessarily be applicable to this product.
 NCBI GI #    21358073
 NCBI GeneID    40384
 NCBI Accession #    NP_649324.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_141067.3 [Other Products]
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 UniProt Primary Accession #    O97143 [Other Products]
 UniProt Secondary Accession #    Q86NL8 [Other Products]
 UniProt Related Accession #    O97143 [Other Products]
 Molecular Weight    85,887 Da
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 NCBI Official Full Name    Sak kinase
 NCBI Official Synonym Full Names    Sak kinase
 NCBI Official Symbol    SAK [Similar Products]
 NCBI Official Synonym Symbols   
CG7186; DmelCG7186; DmSAK; plk4; Plk4; PLK4; sak; Sak; SAK/PLK; Sak/Plk4; SAK/PLK4
[Similar Products]
 NCBI Protein Information    CG7186 gene product from transcript CG7186-RA
 UniProt Protein Name    Serine/threonine-protein kinase PLK4
 UniProt Synonym Protein Names   
Polo-like kinase 4; PLK-4; Serine/threonine-protein kinase SAK
 Protein Family    Staphylokinase
 UniProt Gene Name    SAK [Similar Products]
 UniProt Synonym Gene Names    PLK-4 [Similar Products]
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 UniProt Comments for SAK    Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the mother centriole cylinder, using mother centriole as a platform, leading to the recruitment of centriole biogenesis proteins such as Sas-6. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Centrosome amplification following overexpression can initiate tumorigenesis, highlighting the importance of centrosome regulation in cancers.
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 Research Articles on SAK    1. When Asl reduction is attenuated by Asl overexpression, plk4 mutations, Plk4 RNAi, or Slimb overexpression, Asl levels are higher in spermatozoa, resulting in embryos with reduced viability.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SAK recombinant proteinPathways associated with SAK recombinant protein
 Reference Product  PubMed Publications
 sas-6 recombinant protein  >7 publications with SAK and sas-6
 Sas-4 recombinant protein  >7 publications with SAK and Sas-4
 asl recombinant protein  >4 publications with SAK and asl
 skpA recombinant protein  >1 publications with SAK and skpA
 Products by Pathway  Pathway Diagram
 FoxO Signaling Pathway antibodies  FoxO Signaling Pathway Diagram
Organs/Tissues associated with SAK recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >4 publications with SAK and Testis
 Whole Body Antibodies  >2 publications with SAK and Whole Body
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