NP_001009552.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
62.6 kDa
NCBI Official Full Name
serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
NCBI Official Synonym Full Names
protein phosphatase 2 catalytic subunit beta
NCBI Protein Information
serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
UniProt Protein Name
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
UniProt Synonym Gene Names
UniProt Entry Name
PP2AB_HUMAN
NCBI Summary for PPP2CB
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010]
UniProt Comments for PPP2CB
PPP2CB: one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.
Protein type: EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 8p12
Cellular Component: chromosome, pericentric region; cytosol; nucleus; protein phosphatase type 2A complex; spindle pole
Molecular Function: metal ion binding; protein binding; protein C-terminus binding; protein serine/threonine phosphatase activity
Biological Process: apoptotic mitochondrial changes; fibroblast growth factor receptor signaling pathway; negative regulation of Ras protein signal transduction; proteasomal ubiquitin-dependent protein catabolic process; protein amino acid dephosphorylation; regulation of gene expression; response to antibiotic; response to hydrogen peroxide
Product References and Citations for PPP2CB recombinant protein
The nucleotide sequence of the cDNA encoding the human lung protein phosphatase 2A beta catalytic subunit.Hemmings B.A., Wernet W., Mayer R., Maurer F., Hofsteenge J., Stone S.R.Nucleic Acids Res. 16:11366-11366(1988)
Research Articles on PPP2CB
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Products associated with PPP2CB recombinant protein
Pathways associated with PPP2CB recombinant protein
Diseases associated with PPP2CB recombinant protein
Organs/Tissues associated with PPP2CB recombinant protein
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