Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow PPP1CC  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Jagged 2 Protein (JAG2) Antibody
 • Heat Shock Protein 105 (HSPH1) Antibody
 • CATHEPSIN L (CatL) Kits
 • DCLRE1C - Artemis Antibody
 • Rabbit anti Sheep IgG (heavy and light chains) Secondary Antibody
 • Thyrotropin subunit beta (TSHB) ELISA Kit
 • VEGF Antibody
 • Lymphocyte antigen 6A-2-6E-1 (Ly6a-Ly6) ELISA Kit
 • soluble intercellular adhenaion molecule-1 (sICAM-1) ELISA Kit
 • Basic Leucine Zipper Transcription Factor ATF-Like 3 (BATF3 ... Recombinant Protein
 • SDHB Antibody
 • GRPEL1 Recombinant Protein
 • Acetyl-CoA acetyltransferase (ERG10) Recombinant Protein
 • CPEB1 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

PPP1CC recombinant protein :: Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PPP1CC) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS952100 PPP1CC recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,080 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,080 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,315 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,315 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,700 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,700 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,165 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,165 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PPP1CC), Recombinant Protein

 Also Known As   

Recombinant Human Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PPP1CC)

 Product Synonym Names    Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; PP-1G; EC=3.1.3.16; Protein phosphatase 1C catalytic subunit
 Product Gene Name   

PPP1CC recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence Positions    2-323
 Sequence    ADLDKLNID SIIQRLLEVR GSKPGKNVQL QENEIRGLCL KSREIFLSQP ILLELEAPLK ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL LRGNHECASI NRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL QSMEQIRRIM RPTDVPDQGL LCDLLWSDPD KDVLGWGEND RGVSFTFGAE VVAKFLHKHD LDLICRAHQV VEDGYEFFAK RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAE KKKPNATRPV TPPRGMITKQ AKK
 OMIM    176914
 3D Structure    ModBase 3D Structure for P36873
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
 Species    Homo sapiens (Human)
Section Bar
 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PPP1CC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PPP1CC. It may not necessarily be applicable to this product.
 NCBI GI #    350276247
 NCBI GeneID    5501
 NCBI Accession #    NP_001231903.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001244974.1 [Other Products]
Section Bar
 UniProt Primary Accession #    P36873 [Other Products]
 UniProt Related Accession #    P36873 [Other Products]
 Molecular Weight    38,518 Da
Table BarTOPTable Bar
 NCBI Official Full Name    serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform 2
 NCBI Official Synonym Full Names    protein phosphatase 1, catalytic subunit, gamma isozyme
 NCBI Official Symbol    PPP1CC [Similar Products]
 NCBI Official Synonym Symbols   
PP1C; PP-1G; PPP1G
[Similar Products]
 NCBI Protein Information    serine/threonine-protein phosphatase PP1-gamma catalytic subunit; serine/threonine phosphatase 1 gamma; protein phosphatase 1C catalytic subunit; protein phosphatase 1, catalytic subunit, gamma isoform
 UniProt Protein Name    Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
 UniProt Synonym Protein Names   
Protein phosphatase 1C catalytic subunit
 Protein Family    Serine/threonine-protein phosphatase
 UniProt Gene Name    PPP1CC [Similar Products]
 UniProt Synonym Gene Names    PP-1G [Similar Products]
 UniProt Entry Name    PP1G_HUMAN
Section Bar
 NCBI Summary for PPP1CC    The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Section Bar
 UniProt Comments for PPP1CC    PPP1CC: is a catalytic subunit of protein phosphatase 1 (PP1), a ubiquitous cytosolic serine-threonine phosphatase. Composed a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) which is folded into its native form by inhibitor 2 and glycogen synthetase kinase 3, and then complexed to one or several targeting (or regulatory) subunits: PPP1R12A and PPP1R12B mediate binding to myosin; PPP1R3A, PPP1R3B, PPP1R3C and PPP1R3D mediate binding to glycogen; and PPP1R15A and PPP1R15B mediate binding to EIF2S1. PP1 is essential for cell division, plays critical roles in many cellular processes including glycogen metabolism, muscle contractility and protein synthesis, and is involved in the regulation of ionic conductances and long-term synaptic plasticity. Inhibits the synthesis of proteins involved in synaptic plasticity. Binds to the transcription factor cyclic AMP-dependent response element binding (CREB) and dephosphorylates it. May regulate chromatin condensation through regulation of histone H3 phosphorylation. Differentially expressed in gastric cancer. May participate in the neurodegenerative progress in Alzheimer's disease. Down-regulated in lung squamous cell carcinoma.

Protein type: EC 3.1.3.16; Nucleolus; Motility/polarity/chemotaxis; Protein phosphatase, Ser/Thr (non-receptor)

Chromosomal Location of Human Ortholog: 12q24.1-q24.2

Cellular Component: protein complex; focal adhesion; mitochondrion; cytoplasm; nucleolus; nuclear speck; midbody; nucleus; cytosol; cleavage furrow

Molecular Function: protein binding; metal ion binding; phosphoric monoester hydrolase activity; protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity; protein kinase binding

Biological Process: glycogen metabolic process; cell division; transforming growth factor beta receptor signaling pathway; triacylglycerol catabolic process; circadian regulation of gene expression; mitotic cell cycle; regulation of circadian rhythm; protein amino acid dephosphorylation; negative regulation of transforming growth factor beta receptor signaling pathway; entrainment of circadian clock by photoperiod
Table BarTOPTable Bar
 Research Articles on PPP1CC    1. the lipin-1 N-terminal domain is important for its catalytic activity, nuclear localization, and binding to PP-1cgamma
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with PPP1CC recombinant proteinPathways associated with PPP1CC recombinant protein
 Reference Product  PubMed Publications
 PPP2CA recombinant protein  >2 publications with PPP1CC and PPP2CA
 PPP1R2 recombinant protein  >2 publications with PPP1CC and PPP1R2
 Products by Pathway  Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Aurora B Signaling Pathway antibodies  Aurora B Signaling Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Downregulation Of TGF-beta Receptor Signaling Pathway antibodies  Downregulation Of TGF-beta Receptor Signaling Pathway Diagram
Diseases associated with PPP1CC recombinant proteinOrgans/Tissues associated with PPP1CC recombinant protein
 Disease Name  Pubmed Publications
 Infertility, Male Antibodies  >7 publications with PPP1CC and Infertility, Male
 Neoplasms Antibodies  >2 publications with PPP1CC and Neoplasms
 Ovarian Neoplasms Antibodies  >1 publications with PPP1CC and Ovarian Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >18 publications with PPP1CC and Testis
 Lung Antibodies  >3 publications with PPP1CC and Lung
 Blood Antibodies  >2 publications with PPP1CC and Blood
 Heart Antibodies  >1 publications with PPP1CC and Heart
 Adrenal Gland Antibodies  >1 publications with PPP1CC and Adrenal Gland
 Muscle Antibodies  >1 publications with PPP1CC and Muscle
 Vascular Antibodies  >1 publications with PPP1CC and Vascular
 Skin Antibodies  >1 publications with PPP1CC and Skin
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions