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PPP1CC recombinant protein :: Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PPP1CC) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS952100 PPP1CC recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $730 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $980 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $995 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,075 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,145 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,235 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,250 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,295 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,525 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,805 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,870 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,970 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,400 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PPP1CC), Recombinant Protein

 Also Known As   

Recombinant Human Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PPP1CC)

 Product Gene Name   

PPP1CC recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-323aa, Full Length of Mature Protein
 Sequence    ADLDKLNIDS IIQRLLEVRG SKPGKNVQLQ ENEIRGLCLK SREIFLSQPI LLELEAPLKI CGDIHGQYYD LLRLFEYGGF PPESNYLFLG DYVDRGKQSL ETICLLLAYK IKYPENFFLL RGNHECASIN RIYGFYDECK RRYNIKLWKT FTDCFNCLPI AAIVDEKIFC CHGGLSPDLQ SMEQIRRIMR PTDVPDQGLL CDLLWSDPDK DVLGWGENDR GVSFTFGAEV VAKFLHKHDL DLICRAHQVV EDGYEFFAKR QLVTLFSAPN YCGEFDNAGA MMSVDETLMC SFQILKPAEK KKPNATRPVT PPRGMITKQA KK
 OMIM    176914
 3D Structure    ModBase 3D Structure for P36873
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of PPP1CC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for PPP1CC. It may not necessarily be applicable to this product.
 NCBI GI #    350276247
 NCBI GeneID    5501
 NCBI Accession #    NP_001231903.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001244974.1 [Other Products]
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 UniProt Primary Accession #    P36873 [Other Products]
 UniProt Related Accession #    P36873 [Other Products]
 Molecular Weight    38,518 Da
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 NCBI Official Full Name    serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform 2
 NCBI Official Synonym Full Names    protein phosphatase 1 catalytic subunit gamma
 NCBI Official Symbol    PPP1CC [Similar Products]
 NCBI Official Synonym Symbols   
PP1C; PP-1G; PPP1G
[Similar Products]
 NCBI Protein Information    serine/threonine-protein phosphatase PP1-gamma catalytic subunit
 UniProt Protein Name    Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
 UniProt Synonym Protein Names   
Protein phosphatase 1C catalytic subunit
 Protein Family    Serine/threonine-protein phosphatase
 UniProt Gene Name    PPP1CC [Similar Products]
 UniProt Synonym Gene Names    PP-1G [Similar Products]
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 NCBI Summary for PPP1CC    The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
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 UniProt Comments for PPP1CC    Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).
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 Research Articles on PPP1CC    1. Here the authors show how Ki-67 and RepoMan form mitotic exit phosphatases by recruiting PP1, how they distinguish between distinct PP1 isoforms and how the assembly of these two holoenzymes are dynamically regulated by Aurora B kinase during mitosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PPP1CC recombinant proteinPathways associated with PPP1CC recombinant protein
 Reference Product  PubMed Publications
 PPP2CA recombinant protein  >2 publications with PPP1CC and PPP2CA
 PPP1R2 recombinant protein  >2 publications with PPP1CC and PPP1R2
 Products by Pathway  Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Aurora B Signaling Pathway antibodies  Aurora B Signaling Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
Diseases associated with PPP1CC recombinant proteinOrgans/Tissues associated with PPP1CC recombinant protein
 Disease Name  Pubmed Publications
 Infertility, Male Antibodies  >8 publications with PPP1CC and Infertility, Male
 Infertility, Female Antibodies  >1 publications with PPP1CC and Infertility, Female
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with PPP1CC and Prenatal Exposure Delayed Effects
 Ovarian Neoplasms Antibodies  >1 publications with PPP1CC and Ovarian Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >21 publications with PPP1CC and Testis
 Lung Antibodies  >3 publications with PPP1CC and Lung
 Blood Antibodies  >2 publications with PPP1CC and Blood
 Heart Antibodies  >1 publications with PPP1CC and Heart
 Adrenal Gland Antibodies  >1 publications with PPP1CC and Adrenal Gland
 Muscle Antibodies  >1 publications with PPP1CC and Muscle
 Vascular Antibodies  >1 publications with PPP1CC and Vascular
 Skin Antibodies  >1 publications with PPP1CC and Skin
 Brain Antibodies  >1 publications with PPP1CC and Brain
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