Q9FBI2.2
[Other Products]
UniProt Primary Accession #
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[Other Products]
Molecular Weight
34,814 Da
NCBI Official Full Name
Shiga toxin subunit A
UniProt Protein Name
Shiga toxin subunit A
UniProt Comments for stxA
The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits.
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