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ACADSB recombinant protein :: Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (ACADSB) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS966597 ACADSB recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $810 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,050 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,085 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,200 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,235 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,295 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,330 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,395 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,705 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,910 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,960 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,125 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,520 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (ACADSB), Recombinant Protein

 Also Known As   

Recombinant Human Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (ACADSB)

 Product Gene Name   

ACADSB recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    34-432aa, Full Length of Mature Protein
 Sequence    KSSQSEALLN ITNNGIHFAP LQTFTDEEMM IKSSVKKFAQ EQIAPLVSTM DENSKMEKSV IQGLFQQGLM GIEVDPEYGG TGASFLSTVL VIEELAKVDA SVAVFCEIQN TLINTLIRKH GTEEQKATYL PQLTTEKVGS FCLSEAGAGS DSFALKTRAD KEGDYYVLNG SKMWISSAEH AGLFLVMANV DPTIGYKGIT SFLVDRDTPG LHIGKPENKL GLRASSTCPL TFENVKVPEA NILGQIGHGY KYAIGSLNEG RIGIAAQMLG LAQGCFDYTI PYIKERIQFG KRLFDFQGLQ HQVAHVATQL EAARLLTYNA ARLLEAGKPF IKEASMAKYY ASEIAGQTTS KCIEWMGGVG YTKDYPVEKY FRDAKIGTIY EGASNIQLNT IAKHIDAEY
 OMIM    600301
 3D Structure    ModBase 3D Structure for P45954
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of ACADSB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for ACADSB recombinant protein

   Short
branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa.
NCBI/Uniprot data below describe general gene information for ACADSB. It may not necessarily be applicable to this product.
 NCBI GI #    1054279084
 NCBI GeneID    36
 NCBI Accession #    NP_001317103.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001330174.1 [Other Products]
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 UniProt Primary Accession #    P45954 [Other Products]
 UniProt Secondary Accession #    Q5SQN6; Q96CX7; B4DQ51 [Other Products]
 UniProt Related Accession #    P45954 [Other Products]
 Molecular Weight    36,025 Da
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 NCBI Official Full Name    short/branched chain specific acyl-CoA dehydrogenase, mitochondrial isoform 2
 NCBI Official Synonym Full Names    acyl-CoA dehydrogenase short/branched chain
 NCBI Official Symbol    ACADSB [Similar Products]
 NCBI Official Synonym Symbols   
ACAD7; SBCAD; 2-MEBCAD
[Similar Products]
 NCBI Protein Information    short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
 UniProt Protein Name    Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
 UniProt Synonym Protein Names   
2-methyl branched chain acyl-CoA dehydrogenase; 2-MEBCAD; 2-methylbutyryl-coenzyme A dehydrogenase; 2-methylbutyryl-CoA dehydrogenase
 Protein Family    Short/branched chain specific acyl-CoA dehydrogenase
 UniProt Gene Name    ACADSB [Similar Products]
 UniProt Synonym Gene Names    SBCAD; 2-MEBCAD; 2-methylbutyryl-CoA dehydrogenase [Similar Products]
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 NCBI Summary for ACADSB    Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ACADSB    Has greatest activity toward short branched chain acyl-CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl-CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent.
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 Research Articles on ACADSB    1. the c.1165 A>G mutation before knowing whether the optimal screening cut-off would minimize true positives or false negatives for SBCADD associated with this mutation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ACADSB recombinant proteinPathways associated with ACADSB recombinant protein
 Reference Product  PubMed Publications
 ACAT1 recombinant protein  >1 publications with ACADSB and ACAT1
 Products by Pathway  Pathway Diagram
 Branched-chain Amino Acid Catabolism Pathway antibodies  Branched-chain Amino Acid Catabolism Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Valine, Leucine And Isoleucine Degradation Pathway antibodies  Valine, Leucine And Isoleucine Degradation Pathway Diagram
 Valine, Leucine And Isoleucine Degradation Pathway antibodies  Valine, Leucine And Isoleucine Degradation Pathway Diagram
Diseases associated with ACADSB recombinant protein
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >2 publications with ACADSB and Breast Neoplasms
 2-Methylbutyryl-CoA Dehydrogenase Deficiency Antibodies  >2 publications with ACADSB and 2-Methylbutyryl-CoA Dehydrogenase Deficiency
 Hypertension Antibodies  >1 publications with ACADSB and Hypertension
 Cardiovascular Diseases Antibodies  >1 publications with ACADSB and Cardiovascular Diseases
 Mitochondrial Diseases Antibodies  >1 publications with ACADSB and Mitochondrial Diseases
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