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SRP54 recombinant protein :: Signal recognition particle 54 kDa protein (SRP54) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS950221
SDS-PAGE
Unit / Price
0.05 mg (E-Coli)  /  $925 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $1,000 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,130 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,240 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,355 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,370 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,380 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,435 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,535 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,945 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,055 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,080 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,335 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,700 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Signal recognition particle 54 kDa protein (SRP54), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Signal recognition particle 54 kDa protein (SRP54)

 Product Synonym Names    Recombinant Signal recognition particle 54 kDa protein (SRP54); Signal recognition particle 54 kDa protein; SRP54
 Product Gene Name   

SRP54 recombinant protein

[Similar Products]
 Product Synonym Gene Name    SRP54 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS950221 COA    COA PDF
 Sequence Positions    1-504aa; Full length protein
 Sequence    MVLADLGRKI TSALRSLSNA TIINEEVLNA MLKEVCTALL EADVNIKLVK QLRENVKSAI DLEEMASGLN KRKMIQHAVF KELVKLVDPG VKAWTPTKGK QNVIMFVGLQ GSGKTTTCSK LAYYYQRKGW KTCLICADTF RAGAFDQLKQ NATKARIPFY GSYTEMDPVI IASEGVEKFK NENFEIIIVD TSGRHKQEDS LFEEMLQVAN AIQPDNIVYV MDASIGQACE AQAKAFKDKV DVASVIVTKL DGHAKGGGAL SAVAATKSPI IFIGTGEHID DFEPFKTQPF ISKLLGMGDI EGLIDKVNEL KLDDNEALIE KLKHGQFTLR DMYEQFQNIM KMGPFSQILG MIPGFGTDFM SKGNEQESMA RLKKLMTIMD SMNDQELDST DGAKVFSKQP GRIQRVARGS GVSTRDVQEL LTQYTKFAQM VKKMGGIKGL FKGGDMSKNV SQSQMAKLNQ QMAKMMDPRV LHHMGGMAGL QSMMRQFQQG AAGNMKGMMG FNNM
 Chromosome Location    Chromosome: 14; NC_000014.8 (35452104..35498773). Location: 14q13.2
 OMIM    604857
 3D Structure    ModBase 3D Structure for P61011
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90%(SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degree C. For extended storage, store at -20 or -80 degree C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of SRP54 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for SRP54 recombinant protein

   Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).
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 SDS-PAGE of SRP54 recombinant protein    Recombinant Human Signal recognition particle 54 kDa protein (SRP54)
His-B2M-tagged
E. coli derived
SRP54 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for SRP54. It may not necessarily be applicable to this product.
 NCBI GI #    226371618
 NCBI GeneID    6729
 NCBI Accession #    NP_001139754.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001146282.1 [Other Products]
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 UniProt Primary Accession #    P61011 [Other Products]
 UniProt Secondary Accession #    P13624; B2R759; B4DUW6 [Other Products]
 UniProt Related Accession #    P61011 [Other Products]
 Molecular Weight    72.4kD [Similar Products]
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 NCBI Official Full Name    signal recognition particle 54 kDa protein isoform 2
 NCBI Official Synonym Full Names    signal recognition particle 54kDa
 NCBI Official Symbol    SRP54 [Similar Products]
 NCBI Protein Information    signal recognition particle 54 kDa protein
 UniProt Protein Name    Signal recognition particle 54 kDa protein
 Protein Family    Signal recognition particle
 UniProt Gene Name    SRP54 [Similar Products]
 UniProt Synonym Gene Names    SRP54 [Similar Products]
 UniProt Entry Name    SRP54_HUMAN
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 UniProt Comments for SRP54    SRP54: Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 14q13.2

Cellular Component: cytoplasm; signal recognition particle, endoplasmic reticulum targeting; nucleolus; nuclear speck; cytosol; nucleus

Molecular Function: GTPase activity; ribonucleoprotein binding; GDP binding; GTP binding; drug binding; endoplasmic reticulum signal peptide binding; 7S RNA binding

Biological Process: SRP-dependent cotranslational protein targeting to membrane, translocation; response to drug; protein targeting to ER; SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translation; SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition; gene expression
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 Research Articles on SRP54    1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SRP54 recombinant proteinPathways associated with SRP54 recombinant protein
 Reference Product  PubMed Publications
 SRP19 recombinant protein  >50 publications with SRP54 and SRP19
 RNPS1 recombinant protein  >1 publications with SRP54 and RNPS1
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Protein Export Pathway antibodies  Protein Export Pathway Diagram
 Protein Export Pathway antibodies  Protein Export Pathway Diagram
 SRP-dependent Cotranslational Protein Targeting To Membrane Pathway antibodies  SRP-dependent Cotranslational Protein Targeting To Membrane Pathway Diagram
 Translation Pathway antibodies  Translation Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram
Diseases associated with SRP54 recombinant proteinOrgans/Tissues associated with SRP54 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with SRP54 and Nervous System Diseases
 Kidney Diseases Antibodies  >2 publications with SRP54 and Kidney Diseases
 Inflammation Antibodies  >1 publications with SRP54 and Inflammation
 Bipolar Disorder Antibodies  >1 publications with SRP54 and Bipolar Disorder
 Mood Disorders Antibodies  >1 publications with SRP54 and Mood Disorders
 Depressive Disorder Antibodies  >1 publications with SRP54 and Depressive Disorder
 Drug Toxicity Antibodies  >1 publications with SRP54 and Drug Toxicity
 Necrosis Antibodies  >1 publications with SRP54 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >6 publications with SRP54 and Pancreas
 Kidney Antibodies  >3 publications with SRP54 and Kidney
 Blood Antibodies  >3 publications with SRP54 and Blood
 Nerve Antibodies  >2 publications with SRP54 and Nerve
 Muscle Antibodies  >2 publications with SRP54 and Muscle
 Eye Antibodies  >1 publications with SRP54 and Eye
 Intestine Antibodies  >1 publications with SRP54 and Intestine
 Brain Antibodies  >1 publications with SRP54 and Brain
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