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DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

SCN10A recombinant protein :: Sodium channel protein type 10 subunit alpha (SCN10A) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1165699 SCN10A recombinant protein
Unit / Price
1 mg (E-Coli)  /  $1,375 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,835 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Sodium channel protein type 10 subunit alpha (SCN10A), Recombinant Protein

 Also Known As   

Recombinant Dog Sodium channel protein type 10 subunit alpha (SCN10A), partial

 Product Gene Name   

SCN10A recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for O46669
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Canis familiaris (Dog) (Canis lupus familiaris)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of SCN10A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for SCN10A. It may not necessarily be applicable to this product.
 NCBI GI #    55741729
 NCBI GeneID    477026
 NCBI Accession #    NP_001003203.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001003203.1 [Other Products]
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 UniProt Primary Accession #    O46669 [Other Products]
 UniProt Related Accession #    O46669 [Other Products]
 Molecular Weight    220,702 Da
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 NCBI Official Full Name    sodium channel protein type 10 subunit alpha
 NCBI Official Synonym Full Names    sodium voltage-gated channel alpha subunit 10
 NCBI Official Symbol    SCN10A [Similar Products]
 NCBI Protein Information    sodium channel protein type 10 subunit alpha
 UniProt Protein Name    Sodium channel protein type 10 subunit alpha
 UniProt Synonym Protein Names   
NaNG; Sodium channel protein type X subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.8
 Protein Family    Sodium channel protein
 UniProt Gene Name    SCN10A [Similar Products]
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 UniProt Comments for SCN10A    Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms ().
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 Research Articles on SCN10A    1. Immunohistochemical study was used on canine cardiac ganglionated plexus. Both Nav1.5 and Nav1.8 were expressed in ganglionated plexus with canonical neuronal markers.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with SCN10A recombinant protein
 Disease Name  Pubmed Publications
 Pain Antibodies  >11 publications with SCN10A and Pain
 Arrhythmias, Cardiac Antibodies  >8 publications with SCN10A and Arrhythmias, Cardiac
 Heart Block Antibodies  >5 publications with SCN10A and Heart Block
 Heart Arrest Antibodies  >2 publications with SCN10A and Heart Arrest
 Atrial Fibrillation Antibodies  >2 publications with SCN10A and Atrial Fibrillation
 Ventricular Fibrillation Antibodies  >2 publications with SCN10A and Ventricular Fibrillation
 Hyperalgesia Antibodies  >2 publications with SCN10A and Hyperalgesia
 Heart Failure Antibodies  >1 publications with SCN10A and Heart Failure
 Drug Toxicity Antibodies  >1 publications with SCN10A and Drug Toxicity
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