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FXYD2 recombinant protein :: Sodium/potassium-transporting ATPase subunit gamma Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS7042773 FXYD2 recombinant protein
Unit / Price
0.01 mg  /  $675 +1 FREE 8GB USB
0.05 mg  /  $1,175 +1 FREE 8GB USB
0.1 mg  /  $2,100 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Sodium/potassium-transporting ATPase subunit gamma (FXYD2), Recombinant Protein

 Also Known As   

Sodium/potassium-transporting ATPase subunit gamma

 Product Gene Name   

FXYD2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-66aa; full length protein
 Sequence    MTGLSMDGGG SPKGDVDPFY YDYETVRNGG LIFAGLAFIV GLLILLSRRF RCGGNKKRRQ INEDEP
 OMIM    154020
 3D Structure    ModBase 3D Structure for P54710
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 Host    Cell Free Expression
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 Form/Format    Liquid containing glycerol
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 Species    Homo sapiens (Human)
 Storage Buffer    Tris-based buffer, 50% glycerol.
 Tag Information    Tag type will be determined during the manufacturing process.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of FXYD2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for FXYD2 recombinant protein

   This is a recombinant transmembrane protein expressed in a cell-free expression system.
 Product Categories/Family for FXYD2 recombinant protein    Transmembrane Protein
NCBI/Uniprot data below describe general gene information for FXYD2. It may not necessarily be applicable to this product.
 NCBI GI #    11125766
 NCBI GeneID    486
 NCBI Accession #    NP_001671.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001680.4 [Other Products]
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 UniProt Primary Accession #    P54710 [Other Products]
 UniProt Secondary Accession #    Q15332; Q53YC1; Q9GZP3; Q9GZQ7 [Other Products]
 UniProt Related Accession #    P54710 [Other Products]
 Molecular Weight    7,355 Da
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 NCBI Official Full Name    sodium/potassium-transporting ATPase subunit gamma isoform 1
 NCBI Official Synonym Full Names    FXYD domain containing ion transport regulator 2
 NCBI Official Symbol    FXYD2 [Similar Products]
 NCBI Official Synonym Symbols   
HOMG2; ATP1G1
[Similar Products]
 NCBI Protein Information    sodium/potassium-transporting ATPase subunit gamma
 UniProt Protein Name    Sodium/potassium-transporting ATPase subunit gamma
 UniProt Synonym Protein Names   
FXYD domain-containing ion transport regulator 2; Sodium pump gamma chain
 Protein Family    Sodium/potassium-transporting ATPase
 UniProt Gene Name    FXYD2 [Similar Products]
 UniProt Synonym Gene Names    ATP1C; ATP1G1; Na(+)/K(+) ATPase subunit gamma [Similar Products]
 UniProt Entry Name    ATNG_HUMAN
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 NCBI Summary for FXYD2    This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes the sodium/potassium-transporting ATPase subunit gamma. Mutations in this gene have been associated with Renal Hypomagnesemia-2. Alternatively spliced transcript variants have been described. Read-through transcripts have been observed between this locus and the upstream FXYD domain-containing ion transport regulator 6 (FXYD6, GeneID 53826) locus.[provided by RefSeq, Feb 2011]
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 UniProt Comments for FXYD2    FXYD2: May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. Defects in FXYD2 are the cause of hypomagnesemia type 2 (HOMG2); also known as dominant renal hypomagnesemia or hypomagnesemia with hypocalciuria. HOMG2 is a disorder due to primary renal wasting of magnesium. Plasma levels of other electrolytes are normal. The only abnormality found, in addition to low magnesium levels, is lowered renal excretion of calcium resulting in hypocalciuria. Belongs to the FXYD family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: plasma membrane; sodium:potassium-exchanging ATPase complex

Molecular Function: sodium channel regulator activity; transporter activity

Biological Process: transport

Disease: Hypomagnesemia 2, Renal
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 Research Articles on FXYD2    1. Recurrent FXYD2 p.Gly41Arg mutation is associated with isolated dominant hypomagnesaemia.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FXYD2 recombinant proteinPathways associated with FXYD2 recombinant protein
 Reference Product  PubMed Publications
 FXYD4 recombinant protein  >14 publications with FXYD2 and FXYD4
 FXYD7 recombinant protein  >9 publications with FXYD2 and FXYD7
 FXYD3 recombinant protein  >6 publications with FXYD2 and FXYD3
 ATP1A1 recombinant protein  >2 publications with FXYD2 and ATP1A1
 ATP1B1 recombinant protein  >1 publications with FXYD2 and ATP1B1
 Products by Pathway  Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Carbohydrate Digestion And Absorption Pathway antibodies  Carbohydrate Digestion And Absorption Pathway Diagram
 Carbohydrate Digestion And Absorption Pathway antibodies  Carbohydrate Digestion And Absorption Pathway Diagram
 Cardiac Conduction Pathway antibodies  Cardiac Conduction Pathway Diagram
Diseases associated with FXYD2 recombinant proteinOrgans/Tissues associated with FXYD2 recombinant protein
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >11 publications with FXYD2 and Kidney Diseases
 Magnesium Deficiency Antibodies  >6 publications with FXYD2 and Magnesium Deficiency
 Hypertension Antibodies  >4 publications with FXYD2 and Hypertension
 Insulin Resistance Antibodies  >2 publications with FXYD2 and Insulin Resistance
 Diabetes Mellitus Antibodies  >2 publications with FXYD2 and Diabetes Mellitus
 Hypomagnesemia primary Antibodies  >2 publications with FXYD2 and Hypomagnesemia primary
 Hyperglycemia Antibodies  >1 publications with FXYD2 and Hyperglycemia
 Hypertrophy Antibodies  >1 publications with FXYD2 and Hypertrophy
 Hyperplasia Antibodies  >1 publications with FXYD2 and Hyperplasia
 Inflammation Antibodies  >1 publications with FXYD2 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >60 publications with FXYD2 and Kidney
 Blood Antibodies  >11 publications with FXYD2 and Blood
 Muscle Antibodies  >11 publications with FXYD2 and Muscle
 Heart Antibodies  >8 publications with FXYD2 and Heart
 Brain Antibodies  >7 publications with FXYD2 and Brain
 Pancreas Antibodies  >6 publications with FXYD2 and Pancreas
 Intestine Antibodies  >6 publications with FXYD2 and Intestine
 Embryonic Tissue Antibodies  >3 publications with FXYD2 and Embryonic Tissue
 Liver Antibodies  >2 publications with FXYD2 and Liver
 Connective Tissue Antibodies  >2 publications with FXYD2 and Connective Tissue
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