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SLC12A2 recombinant protein :: Solute carrier family 12 member 2 (SLC12A2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS960013 SLC12A2 recombinant protein
Unit / Price
1 mg (E-Coli)  /  $1,375 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,835 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Solute carrier family 12 member 2 (SLC12A2), Recombinant Protein

 Also Known As   

Recombinant Human Solute carrier family 12 member 2 (SLC12A2) , partial

 Product Gene Name   

SLC12A2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600840
 3D Structure    ModBase 3D Structure for P55011
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of SLC12A2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for SLC12A2. It may not necessarily be applicable to this product.
 NCBI GI #    4506975
 NCBI GeneID    6558
 NCBI Accession #    NP_001037.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001046.2 [Other Products]
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 UniProt Primary Accession #    P55011 [Other Products]
 UniProt Secondary Accession #    Q8N713; Q8WWH7 [Other Products]
 UniProt Related Accession #    P55011 [Other Products]
 Molecular Weight    129,679 Da
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 NCBI Official Full Name    solute carrier family 12 member 2 isoform 1
 NCBI Official Synonym Full Names    solute carrier family 12 member 2
 NCBI Official Symbol    SLC12A2 [Similar Products]
 NCBI Official Synonym Symbols   
BSC; BSC2; NKCC1; PPP1R141
[Similar Products]
 NCBI Protein Information    solute carrier family 12 member 2
 UniProt Protein Name    Solute carrier family 12 member 2
 UniProt Synonym Protein Names   
Basolateral Na-K-Cl symporter; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1
 Protein Family    Solute carrier family
 UniProt Gene Name    SLC12A2 [Similar Products]
 UniProt Synonym Gene Names    NKCC1 [Similar Products]
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 NCBI Summary for SLC12A2    The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
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 UniProt Comments for SLC12A2    Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
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 Research Articles on SLC12A2    1. we introduce the molecular mechanism by which flavonoids, specifically quercetin, act through elevation of [Cl(-) ]c via activation of NKCC1 on important factors controlling various body and cellular functions, such as (1) antihypertensive actions controlling blood volume dependent on the amounts of renal Na(+) reabsorption via expression of the epithelial Na(+) channel
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SLC12A2 recombinant proteinPathways associated with SLC12A2 recombinant protein
 Reference Product  PubMed Publications
 KCNQ1 recombinant protein  >11 publications with SLC12A2 and KCNQ1
 WNK3 recombinant protein  >7 publications with SLC12A2 and WNK3
 OXSR1 recombinant protein  >5 publications with SLC12A2 and OXSR1
 EGF recombinant protein  >3 publications with SLC12A2 and EGF
 JAK2 recombinant protein  >2 publications with SLC12A2 and JAK2
 Products by Pathway  Pathway Diagram
 Cation-coupled Chloride Cotransporters Pathway antibodies  Cation-coupled Chloride Cotransporters Pathway Diagram
 Pancreatic Secretion Pathway antibodies  Pancreatic Secretion Pathway Diagram
 Pancreatic Secretion Pathway antibodies  Pancreatic Secretion Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Salivary Secretion Pathway antibodies  Salivary Secretion Pathway Diagram
 Salivary Secretion Pathway antibodies  Salivary Secretion Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway antibodies  Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway Diagram
 Vibrio Cholerae Infection Pathway antibodies  Vibrio Cholerae Infection Pathway Diagram
 Vibrio Cholerae Infection Pathway antibodies  Vibrio Cholerae Infection Pathway Diagram
Diseases associated with SLC12A2 recombinant proteinOrgans/Tissues associated with SLC12A2 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >90 publications with SLC12A2 and Nervous System Diseases
 Brain Diseases Antibodies  >61 publications with SLC12A2 and Brain Diseases
 Epilepsy Antibodies  >37 publications with SLC12A2 and Epilepsy
 Cardiovascular Diseases Antibodies  >35 publications with SLC12A2 and Cardiovascular Diseases
 Hypertension Antibodies  >25 publications with SLC12A2 and Hypertension
 Disease Models, Animal Antibodies  >23 publications with SLC12A2 and Disease Models, Animal
 Kidney Diseases Antibodies  >20 publications with SLC12A2 and Kidney Diseases
 Edema Antibodies  >17 publications with SLC12A2 and Edema
 Brain Edema Antibodies  >14 publications with SLC12A2 and Brain Edema
 Inflammation Antibodies  >13 publications with SLC12A2 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >159 publications with SLC12A2 and Brain
 Kidney Antibodies  >61 publications with SLC12A2 and Kidney
 Blood Antibodies  >52 publications with SLC12A2 and Blood
 Intestine Antibodies  >34 publications with SLC12A2 and Intestine
 Muscle Antibodies  >32 publications with SLC12A2 and Muscle
 Vascular Antibodies  >31 publications with SLC12A2 and Vascular
 Ear Antibodies  >28 publications with SLC12A2 and Ear
 Spinal Cord Antibodies  >20 publications with SLC12A2 and Spinal Cord
 Lung Antibodies  >19 publications with SLC12A2 and Lung
 Liver Antibodies  >19 publications with SLC12A2 and Liver
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