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SPON1 recombinant protein :: Spondin 1 (SPON1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2018828 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
SDS-PAGE
Unit / Price
0.01 mg  /  $140 +1 FREE 8GB USB
0.05 mg  /  $260 +1 FREE 8GB USB
0.1 mg  /  $400 +1 FREE 8GB USB
0.2 mg  /  $490 +1 FREE 8GB USB
0.5 mg  /  $950 +1 FREE 8GB USB
1 mg  /  $1,405 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Spondin 1 (SPON1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Spondin 1 (SPON1)

 Product Gene Name   

SPON1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    The sequence of the target protein is listed below.
AETS QAEKCMMPEC HTIPCLLSPW SEWSDCSVTC GKGMRTRQRM LKSLAELGDC NEDLEQVEKC MLPECPIDCE LTEWSQWSEC NKSCGKGHVI RTRMIQMEPQ FGGAPCPETV QRKKCRIRKC LRNPSIQKLR WREARESRRS EQLKEESEGE QFPGCRMRPW TAWSECTKLC GGGIQERYMT VKKRFKSSQF TSCKDKKEIR A
 Chromosome Location    Chromosome: 11; NC_000011.9 (13984184..14289679). Location: 11p15.2
 OMIM    604989
 3D Structure    ModBase 3D Structure for Q9HCB6
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 Host    E Coli
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 Purity/Purification    > 95%
 Form/Format    Supplied as lyophilized form in 100mM NaHCO3, 500mM NaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
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 Organism    Homo sapiens (Human)
 Expression System    Prokaryotic expression
 Residues    Ala597~Ala801 (Accession # Q9HCB6) with N-terminal His-Tag
 Subcellular Location    Secreted, extracellular space, extracellular matrix.
 Predicted isoelectric point    8.7
 Predicted Molecular Mass    25.1kDa
 Endotoxin Level    <1.0EU per 1ug (determined by the LAL method)
 Reconstitution    Reconstitute in sterile ddH2O.
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 Preparation and Storage    Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of SPON1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for SPON1 recombinant protein   

SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

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 SDS-PAGE of SPON1 recombinant protein    SPON1 recombinant protein SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for SPON1. It may not necessarily be applicable to this product.
 NCBI GI #    110347423
 NCBI GeneID    10418
 NCBI Accession #    NP_006099.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006108.3 [Other Products]
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 UniProt Primary Accession #    Q9HCB6 [Other Products]
 UniProt Secondary Accession #    O94862; Q8NCD7; Q8WUR5; A8K6W5 [Other Products]
 UniProt Related Accession #    Q9HCB6 [Other Products]
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 NCBI Official Full Name    spondin-1
 NCBI Official Synonym Full Names    spondin 1, extracellular matrix protein
 NCBI Official Symbol    SPON1 [Similar Products]
 NCBI Official Synonym Symbols   
f-spondin; VSGP/F-spondin
[Similar Products]
 NCBI Protein Information    spondin-1; spondin 1, (f-spondin) extracellular matrix protein; vascular smooth muscle cell growth-promoting factor
 UniProt Protein Name    Spondin-1
 UniProt Synonym Protein Names   
F-spondin; Vascular smooth muscle cell growth-promoting factor
 Protein Family    Spondin
 UniProt Gene Name    SPON1 [Similar Products]
 UniProt Synonym Gene Names    KIAA0762; VSGP [Similar Products]
 UniProt Entry Name    SPON1_HUMAN
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 UniProt Comments for SPON1    SPON1: Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS. Major factor for vascular smooth muscle cell.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11p15.2

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; endoplasmic reticulum lumen

Molecular Function: protein binding

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; cell adhesion; post-translational protein modification
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 Research Articles on SPON1    1. Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SPON1 recombinant proteinDiseases associated with SPON1 recombinant protein
 Reference Product  PubMed Publications
 APP recombinant protein  >3 publications with SPON1 and APP
 APOE recombinant protein  >1 publications with SPON1 and APOE
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with SPON1 and Neoplasms
 Cardiovascular Diseases Antibodies  >4 publications with SPON1 and Cardiovascular Diseases
 Carcinoma Antibodies  >4 publications with SPON1 and Carcinoma
 Ovarian Neoplasms Antibodies  >4 publications with SPON1 and Ovarian Neoplasms
 Nervous System Diseases Antibodies  >3 publications with SPON1 and Nervous System Diseases
 Hypertension Antibodies  >3 publications with SPON1 and Hypertension
 Necrosis Antibodies  >2 publications with SPON1 and Necrosis
 Brain Diseases Antibodies  >2 publications with SPON1 and Brain Diseases
 Disease Models, Animal Antibodies  >1 publications with SPON1 and Disease Models, Animal
 Breast Neoplasms Antibodies  >1 publications with SPON1 and Breast Neoplasms
Organs/Tissues associated with SPON1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >7 publications with SPON1 and Vascular
 Nerve Antibodies  >7 publications with SPON1 and Nerve
 Muscle Antibodies  >6 publications with SPON1 and Muscle
 Brain Antibodies  >6 publications with SPON1 and Brain
 Embryonic Tissue Antibodies  >5 publications with SPON1 and Embryonic Tissue
 Mouth Antibodies  >4 publications with SPON1 and Mouth
 Kidney Antibodies  >2 publications with SPON1 and Kidney
 Eye Antibodies  >2 publications with SPON1 and Eye
 Ovary Antibodies  >2 publications with SPON1 and Ovary
 Heart Antibodies  >1 publications with SPON1 and Heart
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