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Nr5a1 recombinant protein :: Steroidogenic factor 1 (Nr5a1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS965782 Nr5a1 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $880 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,100 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,300 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,305 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,345 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,395 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,480 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,850 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,995 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,035 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,250 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,630 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Steroidogenic factor 1 (Nr5a1), Recombinant Protein

 Also Known As   

Recombinant Rat Steroidogenic factor 1 (Nr5a1)

 Product Gene Name   

Nr5a1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-462aa, Full length protein
 Sequence    MDYSYDEDLD ELCPVCGDKV SGYHYGLLTC ESCKGFFKRT VQNNKHYTCT ESQSCKIDKT QRKRCPFCRF QKCLTVGMRL EAVRADRMRG GRNKFGPMYK RDRALKQQKK AQIRANGFKL ETGPPMGVPP PPPPPPDYML PPSLHAPEPK ALVSGPPSGP LGDFGAPSLP MAVPGPHGPL AGYLYPAFSN RTIKSEYPEP YASPPQQPGP PYSYPEPFSG GPNVPELILQ LLQLEPEEDQ VRARIVGCLQ EPAKSRPDQP APFSLLCRMA DQTFISIVDW ARRCMVFKEL EVADQMTLLQ NCWSELLVLD HIYRQVQYGK EDSILLVTGQ EVELSTVAVQ AGSLLHSLVL RAQELVLQLH ALQLDRQEFV CLKFLILFSL DVKFLNNHSL VKDAQEKANA ALLDYTLCHY PHCGDKFQQL LLCLVEVRAL SMQAKEYLYH KHLGNEMPRN NLLIEMLQAK QT
 3D Structure    ModBase 3D Structure for P50569
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rat
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Nr5a1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Nr5a1 recombinant protein

   This protein is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect.
NCBI/Uniprot data below describe general gene information for Nr5a1. It may not necessarily be applicable to this product.
 NCBI GI #    300797824
 NCBI GeneID    83826
 NCBI Accession #    NP_001178028.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001191099.1 [Other Products]
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 UniProt Primary Accession #    P50569 [Other Products]
 UniProt Related Accession #    P50569 [Other Products]
 Molecular Weight    52,087 Da
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 NCBI Official Full Name    steroidogenic factor 1
 NCBI Official Synonym Full Names    nuclear receptor subfamily 5, group A, member 1
 NCBI Official Symbol    Nr5a1 [Similar Products]
 NCBI Official Synonym Symbols   
Sf-1; Ad4bp; Ftzf1; Ad4BP/SF-1
[Similar Products]
 NCBI Protein Information    steroidogenic factor 1
 UniProt Protein Name    Steroidogenic factor 1
 UniProt Synonym Protein Names   
Adrenal 4-binding protein; Fushi tarazu factor homolog 1; Nuclear receptor subfamily 5 group A member 1; Steroid hormone receptor Ad4BP
 Protein Family    Steroidogenic factor
 UniProt Gene Name    Nr5a1 [Similar Products]
 UniProt Synonym Gene Names    Ftzf1; SF-1; STF-1 [Similar Products]
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 NCBI Summary for Nr5a1    transcription factor; essential for adrenal and gonadal development [RGD, Feb 2006]
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 UniProt Comments for Nr5a1    Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity. Binds phosphatidylcholine and phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3. Activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation ().
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 Research Articles on Nr5a1    1. DNA methylation might play a role in the downregulation of SF-1 gene expression induced by soy isoflavones.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Nr5a1 recombinant proteinPathways associated with Nr5a1 recombinant protein
 Reference Product  PubMed Publications
 Nr0b1 recombinant protein  >74 publications with Nr5a1 and Nr0b1
 Esr1 recombinant protein  >3 publications with Nr5a1 and Esr1
 Lhb recombinant protein  >3 publications with Nr5a1 and Lhb
 Nr0b2 recombinant protein  >2 publications with Nr5a1 and Nr0b2
 Pgr recombinant protein  >1 publications with Nr5a1 and Pgr
 Nr1h4 recombinant protein  >1 publications with Nr5a1 and Nr1h4
 Products by Pathway  Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Nuclear Receptor Transcription Pathway antibodies  Nuclear Receptor Transcription Pathway Diagram
 Nuclear Receptors Pathway antibodies  Nuclear Receptors Pathway Diagram
 Ovarian Infertility Genes Pathway antibodies  Ovarian Infertility Genes Pathway Diagram
 Wnt Signaling Pathway NetPath antibodies  Wnt Signaling Pathway NetPath Diagram
Diseases associated with Nr5a1 recombinant proteinOrgans/Tissues associated with Nr5a1 recombinant protein
 Disease Name  Pubmed Publications
 Gonadal Disorders Antibodies  >86 publications with Nr5a1 and Gonadal Disorders
 Disorders of Sex Development Antibodies  >59 publications with Nr5a1 and Disorders of Sex Development
 Neoplasms Antibodies  >55 publications with Nr5a1 and Neoplasms
 Urogenital Abnormalities Antibodies  >51 publications with Nr5a1 and Urogenital Abnormalities
 Adrenal Insufficiency Antibodies  >38 publications with Nr5a1 and Adrenal Insufficiency
 Carcinoma Antibodies  >29 publications with Nr5a1 and Carcinoma
 Gonadal Dysgenesis, 46,XY Antibodies  >26 publications with Nr5a1 and Gonadal Dysgenesis, 46,XY
 46,XY SEX REVERSAL 3 Antibodies  >24 publications with Nr5a1 and 46,XY SEX REVERSAL 3
 Genital Diseases, Male Antibodies  >19 publications with Nr5a1 and Genital Diseases, Male
 Primary Ovarian Insufficiency Antibodies  >14 publications with Nr5a1 and Primary Ovarian Insufficiency
 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >107 publications with Nr5a1 and Ovary
 Brain Antibodies  >57 publications with Nr5a1 and Brain
 Pituitary Gland Antibodies  >39 publications with Nr5a1 and Pituitary Gland
 Spleen Antibodies  >13 publications with Nr5a1 and Spleen
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