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Stra6 recombinant protein :: Stimulated by retinoic acid gene 6 protein (Stra6) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1196556 Stra6 recombinant protein
Unit / Price
1 mg (E-Coli)  /  $1,260 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Stimulated by retinoic acid gene 6 protein (Stra6), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Mouse Stimulated by retinoic acid gene 6 protein (Stra6), partial

 Product Gene Name   

Stra6 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for O70491
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mus musculus (Mouse)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Stra6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Stra6. It may not necessarily be applicable to this product.
 NCBI GI #    242332599
 NCBI GeneID    20897
 NCBI Accession #    NP_001155947.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001162475.1 [Other Products]
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 UniProt Primary Accession #    O70491 [Other Products]
 UniProt Secondary Accession #    Q6DIA8 [Other Products]
 UniProt Related Accession #    O70491 [Other Products]
 Molecular Weight    73,775 Da
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 NCBI Official Full Name    receptor for retinol uptake STRA6
 NCBI Official Synonym Full Names    stimulated by retinoic acid gene 6
 NCBI Official Symbol    Stra6 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    receptor for retinol uptake STRA6; stimulated by retinoic acid gene 6 protein
 UniProt Protein Name    Receptor for retinol uptake STRA6
 UniProt Synonym Protein Names   
Retinoic acid-responsive protein; Retinol-binding protein receptor STRA6; Stimulated by retinoic acid gene 6 protein
 Protein Family    Stimulated by retinoic acid gene 6 protein
 UniProt Gene Name    Stra6 [Similar Products]
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 UniProt Comments for Stra6    Functions as retinol transporter (PubMed:23839944, PubMed:24852372). Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A (). Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin (PubMed:21368206, PubMed:23839944). Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid and 11-cis-retinal (PubMed:22467576, PubMed:24852372). STRA6-mediated transport is particularly important in the eye, and under conditions of dietary vitamin A deficiency (PubMed:22467576, PubMed:23839944, PubMed:24852372). Does not transport retinoic acid ().
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 Research Articles on Stra6    1. The STRA6 is potent regulators of diurnal insulin responses and suggest that the holo-RBP/STRA6 signaling axis may represent a novel therapeutic target in type II diabetes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with Stra6 recombinant proteinOrgans/Tissues associated with Stra6 recombinant protein
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >10 publications with Stra6 and Congenital Abnormalities
 Eye Abnormalities Antibodies  >8 publications with Stra6 and Eye Abnormalities
 Abnormalities, Multiple Antibodies  >7 publications with Stra6 and Abnormalities, Multiple
 Vitamin A Deficiency Antibodies  >4 publications with Stra6 and Vitamin A Deficiency
 Neoplasms Antibodies  >4 publications with Stra6 and Neoplasms
 Carcinoma Antibodies  >4 publications with Stra6 and Carcinoma
 Hernia, Diaphragmatic Antibodies  >4 publications with Stra6 and Hernia, Diaphragmatic
 Cardiovascular Abnormalities Antibodies  >4 publications with Stra6 and Cardiovascular Abnormalities
 Lung Diseases Antibodies  >3 publications with Stra6 and Lung Diseases
 Carcinoma, Embryonal Antibodies  >3 publications with Stra6 and Carcinoma, Embryonal
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >12 publications with Stra6 and Eye
 Brain Antibodies  >8 publications with Stra6 and Brain
 Lung Antibodies  >7 publications with Stra6 and Lung
 Heart Antibodies  >5 publications with Stra6 and Heart
 Placenta Antibodies  >5 publications with Stra6 and Placenta
 Spleen Antibodies  >1 publications with Stra6 and Spleen
 Prostate Antibodies  >1 publications with Stra6 and Prostate
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