P52840.1
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
Sulfotransferase 1A1
NCBI Official Synonym Full Names
sulfotransferase family 1A, phenol-preferring, member 1
NCBI Official Synonym Symbols
PST; Stp; Stp1; ST1A1; AI266890 [Similar Products]
NCBI Protein Information
sulfotransferase 1A1; ST1A4; mSTp1; sulfokinase; aryl sulfotransferase; phenol sulfotransferase; arylsulfotransferase ST1A4; phenol/aryl sulfotransferase; sulfotransferase, phenol preferring 1
UniProt Protein Name
Sulfotransferase 1A1
UniProt Synonym Protein Names
Aryl sulfotransferase; Phenol sulfotransferase; Phenol/aryl sulfotransferase; mSTp1; ST1A4; Sulfokinase
UniProt Synonym Gene Names
UniProt Entry Name
ST1A1_MOUSE
UniProt Comments for Sult1a1
SULT1A1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N- hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk. Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.8.2.1; Transferase; Energy Metabolism - sulfur
Cellular Component: cytoplasm; cytosol
Molecular Function: phenanthrol sulfotransferase activity; protein homodimerization activity; trans-3,4-dihydrodiolphenanthrene sulfotransferase activity; proteoglycan sulfotransferase activity; 3'-phosphoadenosine 5'-phosphosulfate binding; 2-phenanthrol sulfotransferase activity; nucleotide binding; galactose 3-O-sulfotransferase activity; tyrosine-ester sulfotransferase activity; aryl sulfotransferase activity; 1-phenanthrol sulfotransferase activity; transferase activity; 3-phenanthrol sulfotransferase activity; sulfotransferase activity; HNK-1 sulfotransferase activity; N-acetylglucosamine 6-O-sulfotransferase activity; 4-phenanthrol sulfotransferase activity; trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity; heparan sulfate 2-O-sulfotransferase activity; cholesterol sulfotransferase activity; N-acetylgalactosamine 4-O-sulfotransferase activity; 9-phenanthrol sulfotransferase activity; heparan sulfate 6-O-sulfotransferase activity
Biological Process: steroid metabolic process; estrogen metabolic process; xenobiotic metabolic process; sulfation; 4-nitrophenol metabolic process; response to glucocorticoid stimulus; catecholamine metabolic process; lipid metabolic process; drug metabolic process
Research Articles on Sult1a1
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Pathways associated with Sult1a1 recombinant protein
Organs/Tissues associated with Sult1a1 recombinant protein
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