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SULT2B1 recombinant protein :: Sulfotransferase Family Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS144060 SULT2B1 recombinant protein
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.025 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $2,235 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Sulfotransferase Family (SULT2B1), Recombinant Protein

 Also Known As   

Recombinant Human Sulfotransferase Family, Cytosolic, 2B, Member 1

 Product Synonym Names    SULT2B1 Human; Sulfotransferase Family, Cytosolic, 2B, Member 1 Human Recombinant; SULT2B1; HSST2; EC 2.8.2.2; Sulfotransferase 2B1; Hydroxysteroid sulfotransferase 2; ST2B1; Sulfotransferase family cytosolic 2B member 1
 Product Gene Name   

SULT2B1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MDGPAEPQIP GLWDTYEDDI SEISQKLPGE YFRYKGVPFP VGLYSLESIS LAENTQDVRD DDIFIITYPK SGTTWMIEII CLILKEGDPS WIRSVPIWER APWCETIVGA FSLPDQYSPR LMSSHLPIQI FTKAFFSSKA KVIYMGRNPR DVVVSLYHYS KIAGQLKDPG TPDQFLRDFL KGEVQFGSWF DHIKGWLRMK GKDNFLFITY EELQQDLQGS VERICGFLGR PLGKEALGSV VAHSTFSAMK ANTMSNYTLL PPSLLDHRRG AFLRKGVCGD WKNHFTVAQS EAFDRAYRKQ MRGMPTFPWD EDPEEDGSPD PEPSPEPEPK PSLEPNTSLE REPRPNSSPS PSPGQASETP HPRPS.
 OMIM    604125
 3D Structure    ModBase 3D Structure for O00204
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 Host    E Coli
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 Purity/Purification    Greater than 85% as determined by SDS-PAGE.
 Form/Format    (SULT2B1 Human solution containing 20mM Trsi HCL pH-7.5, & 10% glycerol.
Sterile filtered colorless solution.
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 Preparation and Storage    SULT2B1 Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
 Other Notes    Small volumes of SULT2B1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for SULT2B1 recombinant protein

   Description: SULT2B1 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 365 amino acids (1-365 a.a.) and having a molecular mass of 41.3 kDa. SULT2B1 protein is purified by standard chromatography.

Introduction: SULT2B1 catalyzes the sulfate conjugation of numerous hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation enhances the water solubility of molecules, and therefore their renal excretion, however it can also result in bioactivation to form active metabolites. SULT2B1b is localized in the cytosol and nuclei of human cells. SULT2B1b is selective for the sulfation of 3beta-hydroxysteroids such as dehydroepiandrosterone and pregnenolone, and participates in cholesterol sulfation in human skin.
 Product Categories/Family for SULT2B1 recombinant protein    ENZYMES; Enzymes; Transferase
NCBI/Uniprot data below describe general gene information for SULT2B1. It may not necessarily be applicable to this product.
 NCBI GI #    31563388
 NCBI GeneID    6820
 NCBI Accession #    NP_004596.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004605.2 [Other Products]
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 UniProt Primary Accession #    O00204 [Other Products]
 UniProt Secondary Accession #    O00205; O75814 [Other Products]
 UniProt Related Accession #    O00204 [Other Products]
 Molecular Weight    39,599 Da
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 NCBI Official Full Name    sulfotransferase family cytosolic 2B member 1 isoform a
 NCBI Official Synonym Full Names    sulfotransferase family, cytosolic, 2B, member 1
 NCBI Official Symbol    SULT2B1 [Similar Products]
 NCBI Official Synonym Symbols   
HSST2
[Similar Products]
 NCBI Protein Information    sulfotransferase family cytosolic 2B member 1; ST2B1; alcohol sulfotransferase; hydroxysteroid sulfotransferase 2; sulfotransferase 2B1
 UniProt Protein Name    Sulfotransferase family cytosolic 2B member 1
 UniProt Synonym Protein Names   
Alcohol sulfotransferase; Hydroxysteroid sulfotransferase 2
 Protein Family    Sulfotransferase family cytosolic
 UniProt Gene Name    SULT2B1 [Similar Products]
 UniProt Synonym Gene Names    HSST2; ST2B1; Sulfotransferase 2B1 [Similar Products]
 UniProt Entry Name    ST2B1_HUMAN
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 NCBI Summary for SULT2B1    Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for SULT2B1    SULT2B1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.8.2.2; Lipid Metabolism - androgen and estrogen; Energy Metabolism - sulfur; Transferase

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; nucleus; cytosol

Molecular Function: protein binding; alcohol sulfotransferase activity; steroid sulfotransferase activity

Biological Process: steroid metabolic process; sulfate assimilation; xenobiotic metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process
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 Research Articles on SULT2B1    1. This study identified specific germline variations in estradiol metabolism-related pathways, namely CYP1B1, SULT2B1, and HSD17B2, as novel prognostic markers that are cumulatively associated with increased risk of prostate cancer progression
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SULT2B1 recombinant proteinPathways associated with SULT2B1 recombinant protein
 Reference Product  PubMed Publications
 CYP3A5 recombinant protein  >5 publications with SULT2B1 and CYP3A5
 CYP3A7 recombinant protein  >3 publications with SULT2B1 and CYP3A7
 STS recombinant protein  >3 publications with SULT2B1 and STS
 CYP1A1 recombinant protein  >2 publications with SULT2B1 and CYP1A1
 CYP17A1 recombinant protein  >1 publications with SULT2B1 and CYP17A1
 CYP3A43 recombinant protein  >1 publications with SULT2B1 and CYP3A43
 CYP3A4 recombinant protein  >1 publications with SULT2B1 and CYP3A4
 CYP7A1 recombinant protein  >1 publications with SULT2B1 and CYP7A1
 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Cytosolic Sulfonation Of Small Molecules Pathway antibodies  Cytosolic Sulfonation Of Small Molecules Pathway Diagram
 Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway antibodies  Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway Diagram
 Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway antibodies  Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway Diagram
 Defective GGT1 Causes Glutathionuria (GLUTH) Pathway antibodies  Defective GGT1 Causes Glutathionuria (GLUTH) Pathway Diagram
 Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway antibodies  Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway Diagram
 Defective MAT1A Causes Methionine Adenosyltransferase Deficiency (MATD) Pathway antibodies  Defective MAT1A Causes Methionine Adenosyltransferase Deficiency (MATD) Pathway Diagram
 Defective OPLAH Causes 5-oxoprolinase Deficiency (OPLAHD) Pathway antibodies  Defective OPLAH Causes 5-oxoprolinase Deficiency (OPLAHD) Pathway Diagram
 Defective SLC35D1 Causes Schneckenbecken Dysplasia (SCHBCKD) Pathway antibodies  Defective SLC35D1 Causes Schneckenbecken Dysplasia (SCHBCKD) Pathway Diagram
 Defective TPMT Causes Thiopurine S-methyltransferase Deficiency (TPMT Deficiency) Pathway antibodies  Defective TPMT Causes Thiopurine S-methyltransferase Deficiency (TPMT Deficiency) Pathway Diagram
Diseases associated with SULT2B1 recombinant proteinOrgans/Tissues associated with SULT2B1 recombinant protein
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >7 publications with SULT2B1 and Carcinoma
 Breast Neoplasms Antibodies  >6 publications with SULT2B1 and Breast Neoplasms
 Adenocarcinoma Antibodies  >6 publications with SULT2B1 and Adenocarcinoma
 Genital Diseases, Male Antibodies  >3 publications with SULT2B1 and Genital Diseases, Male
 Liver Neoplasms Antibodies  >3 publications with SULT2B1 and Liver Neoplasms
 Prostatic Neoplasms Antibodies  >3 publications with SULT2B1 and Prostatic Neoplasms
 Hyperplasia Antibodies  >2 publications with SULT2B1 and Hyperplasia
 Liver Diseases Antibodies  >2 publications with SULT2B1 and Liver Diseases
 Pregnancy Complications Antibodies  >2 publications with SULT2B1 and Pregnancy Complications
 Nervous System Diseases Antibodies  >1 publications with SULT2B1 and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >10 publications with SULT2B1 and Skin
 Intestine Antibodies  >7 publications with SULT2B1 and Intestine
 Prostate Antibodies  >7 publications with SULT2B1 and Prostate
 Brain Antibodies  >6 publications with SULT2B1 and Brain
 Placenta Antibodies  >5 publications with SULT2B1 and Placenta
 Lung Antibodies  >4 publications with SULT2B1 and Lung
 Testis Antibodies  >4 publications with SULT2B1 and Testis
 Kidney Antibodies  >2 publications with SULT2B1 and Kidney
 Stomach Antibodies  >1 publications with SULT2B1 and Stomach
 Connective Tissue Antibodies  >1 publications with SULT2B1 and Connective Tissue
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