NP_079955.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,522 Da
NCBI Official Full Name
suppressor of IKBKE 1
NCBI Official Synonym Full Names
suppressor of IKBKE 1
NCBI Official Synonym Symbols
Sike; Sikeb; AI450236; AI839862; 2810005O12Rik; 5730470L24Rik [Similar Products]
NCBI Protein Information
suppressor of IKBKE 1
UniProt Protein Name
Suppressor of IKBKE 1
UniProt Synonym Protein Names
Suppressor of IKK-epsilon
UniProt Comments for Sike1
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways ().
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Pathways associated with Sike1 recombinant protein
Diseases associated with Sike1 recombinant protein
Organs/Tissues associated with Sike1 recombinant protein
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