NP_001027392.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
111.3 kDa
NCBI Official Full Name
syntaxin-binding protein 1 isoform b
NCBI Official Synonym Full Names
syntaxin binding protein 1
NCBI Official Synonym Symbols
P67; NSEC1; UNC18; RBSEC1; MUNC18-1 [Similar Products]
NCBI Protein Information
syntaxin-binding protein 1
UniProt Protein Name
Syntaxin-binding protein 1
UniProt Synonym Protein Names
MUNC18-1; N-Sec1; Protein unc-18 homolog 1; Unc18-1; Protein unc-18 homolog A; Unc-18A; p67
UniProt Synonym Gene Names
NCBI Summary for STXBP1
This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]
UniProt Comments for STXBP1
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
Research Articles on STXBP1
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Products associated with STXBP1 recombinant protein
Pathways associated with STXBP1 recombinant protein
Diseases associated with STXBP1 recombinant protein
Organs/Tissues associated with STXBP1 recombinant protein
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