NP_001081671.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
51,963 Da
NCBI Official Full Name
T-box protein VegT-B
NCBI Official Synonym Full Names
vegt protein S homeolog
NCBI Official Synonym Symbols
Apod; brat; vegt; tVegT; xombi; vegt-a; vegt-b; antipodean [Similar Products]
NCBI Protein Information
T-box protein VegT-B
UniProt Protein Name
T-box protein VegT-B
UniProt Synonym Protein Names
Xenopus optomotor blind
UniProt Synonym Gene Names
UniProt Comments for vegt-b
Transcription factor required for both mesoderm and endoderm formation in the embryo; signaling determinants and concentration levels may determine which germ layer is formed. Acts together with beta-catenin to activate genes that are responsible for mesoderm induction including wnt-8, eomes t/bra, siamois, mix1 and sox17. Directly binds to promoter DNA. Patterns the mesoderm along the dorsoventral and posterior axis. Activates siamois gene transcription when alone or in combination with beta-catenin, but inhibits siamois transcription in combination with pou5f1.1/oct-25.
Research Articles on vegt-b
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