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Tbx19 recombinant protein :: T-box transcription factor TBX19 (Tbx19) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1294444 Tbx19 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $865 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,085 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,155 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,275 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,290 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,335 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,375 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,460 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,810 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,975 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,015 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,220 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,600 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

T-box transcription factor TBX19 (Tbx19), Recombinant Protein

 Also Known As   

Recombinant Mouse T-box transcription factor TBX19 (Tbx19)

 Product Gene Name   

Tbx19 recombinant protein

[Similar Products]
 Product Synonym Gene Name    Tbx19 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-446aa, full length protein
 Sequence    MSELATQKAG EGTVSRLLNV VESELQAGRE KGDPTEKQLQ IILEDAPLWQ RFKEVTNEMI VTKNGRRMFP VLKISVTGLD PNAMYSLLLD FVRTDSHRWK YVNGEWVPAG KPEVSSHSCV YIHPDSPNFG AHWMKAPISF SKVKLTNKLN GGGQIMLNSL HKYEPQVHIV RVGGAHRMVM NCSFPETQFI AVTAYQNEEI TALKIKYNPF AKAFLDAKER NHLKDVPEAI SESQHVTYSH LGGWILSNPD GVCTAANSNY QYATPLPLPA PHTHHGCEHY AGLRGHRQAP YPSAYMHRNH SPSVNLIESS SNNLQVFSGP DSWTSLSSTP HASILSVPHS NGPINPGPSP YPCLWTISNG GGGPVASGSE VHASTSGTIL LGNPAVTSPS SLLPTQATTS AGVEVLGEPS LTSIAVSTWT AVASHPLPGW GGPGGAGRHS SSSLDS
 3D Structure    ModBase 3D Structure for Q99ME7
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Tbx19 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Tbx19 recombinant protein

   This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure.
NCBI/Uniprot data below describe general gene information for Tbx19. It may not necessarily be applicable to this product.
 NCBI GI #    14030783
 NCBI GeneID    83993
 NCBI Accession #    NP_114394.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_032005.4 [Other Products]
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 UniProt Primary Accession #    Q99ME7 [Other Products]
 UniProt Secondary Accession #    Q0VBH2 [Other Products]
 UniProt Related Accession #    Q99ME7 [Other Products]
 Molecular Weight    48,037 Da
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 NCBI Official Full Name    T-box transcription factor TBX19
 NCBI Official Synonym Full Names    T-box 19
 NCBI Official Symbol    Tbx19 [Similar Products]
 NCBI Official Synonym Symbols   
Tpit; AU019250; D1Ertd754e
[Similar Products]
 NCBI Protein Information    T-box transcription factor TBX19
 UniProt Protein Name    T-box transcription factor TBX19
 UniProt Synonym Protein Names   
T-box factor, pituitary
 Protein Family    T-box transcription factor
 UniProt Gene Name    Tbx19 [Similar Products]
 UniProt Synonym Gene Names    Tpit; T-box protein 19 [Similar Products]
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 NCBI Summary for Tbx19    This gene encodes a member of a family of transcription factors containing a characteristic T-box DNA-binding domain. The encoded protein promotes expression of the pro-opiomelanocortin (POMC) gene, which is important for the differentiation of cells in the pituitary gland. [provided by RefSeq, Mar 2013]
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 UniProt Comments for Tbx19    Transcriptional regulator involved in developmental processes. Can activate POMC gene expression and repress the alpha glycoprotein subunit and thyroid-stimulating hormone beta promoters.
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 Research Articles on Tbx19    1. The coordinate expression of Etv1 with POMC cell differentiation and its interaction with the highly cell-restricted Tpit factor indicate that Etv1 participates in a combinatorial code for pituitary cell-specific gene expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with Tbx19 recombinant proteinOrgans/Tissues associated with Tbx19 recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >19 publications with Tbx19 and Nervous System Diseases
 Brain Diseases Antibodies  >18 publications with Tbx19 and Brain Diseases
 ACTH DEFICIENCY, ISOLATED Antibodies  >14 publications with Tbx19 and ACTH DEFICIENCY, ISOLATED
 Hypopituitarism Antibodies  >8 publications with Tbx19 and Hypopituitarism
 Adrenal Insufficiency Antibodies  >4 publications with Tbx19 and Adrenal Insufficiency
 Immune System Diseases Antibodies  >2 publications with Tbx19 and Immune System Diseases
 Adrenocorticotropic hormone deficiency Antibodies  >2 publications with Tbx19 and Adrenocorticotropic hormone deficiency
 Heart Diseases Antibodies  >1 publications with Tbx19 and Heart Diseases
 Craniofacial Abnormalities Antibodies  >1 publications with Tbx19 and Craniofacial Abnormalities
 Weight Loss Antibodies  >1 publications with Tbx19 and Weight Loss
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >26 publications with Tbx19 and Brain
 Pituitary Gland Antibodies  >25 publications with Tbx19 and Pituitary Gland
 Embryonic Tissue Antibodies  >2 publications with Tbx19 and Embryonic Tissue
 Thymus Antibodies  >1 publications with Tbx19 and Thymus
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