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TBX20 recombinant protein :: T-box transcription factor TBX20 (TBX20) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1416032 TBX20 recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $865 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $960 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,085 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,155 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,275 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,290 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,335 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,380 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,460 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,815 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,975 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,015 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,220 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,600 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

T-box transcription factor TBX20 (TBX20), Recombinant Protein

 Also Known As   

Recombinant Human T-box transcription factor TBX20 (TBX20)

 Product Synonym Names    T-box transcription factor TBX20; T-box protein 20
 Product Gene Name   

TBX20 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-447aa; full length protein
 Sequence    MEFTASPKPQ LSSRANAFSI AALMSSGGSK EKEATENTIK PLEQFVEKSS CAQPLGELTS LDAHGEFGGG SGSSPSSSSL CTEPLIPTTP IIPSEEMAKI ACSLETKELW DKFHELGTEM IITKSGRRMF PTIRVSFSGV DPEAKYIVLM DIVPVDNKRY RYAYHRSSWL VAGKADPPLP ARLYVHPDSP FTGEQLLKQM VSFEKVKLTN NELDQHGHII LNSMHKYQPR VHIIKKKDHT ASLLNLKSEE FRTFIFPETV FTAVTAYQNQ LITKLKIDSN PFAKGFRDSS RLTDIERESV ESLIQKHSYA RSPIRTYGGE EDVLGDESQT TPNRGSAFTT SDNLSLSSWV SSSSSFPGFQ HPQSLTALGT STASIATPIP HPIQGSLPPY SRLGMPLTPS AIASSMQGSG PTFPSFHMPR YHHYFQQGPY AAIQGLRHSS AVMTPFV
 OMIM    gene 611363
 3D Structure    ModBase 3D Structure for Q9UMR3
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >=90% (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TBX20 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for TBX20 recombinant protein

   This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for TBX20. It may not necessarily be applicable to this product.
 NCBI GI #    117676399
 NCBI GeneID    57057
 NCBI Accession #    NP_001071121.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001077653.2 [Other Products]
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 UniProt Primary Accession #    Q9UMR3 [Other Products]
 UniProt Secondary Accession #    Q000T4; Q0IJ70; Q0VAS1; Q9Y2N5; A4D1Y6 [Other Products]
 UniProt Related Accession #    Q9UMR3 [Other Products]
 Molecular Weight    49,232 Da
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 NCBI Official Full Name    T-box transcription factor TBX20 isoform 1
 NCBI Official Synonym Full Names    T-box 20
 NCBI Official Symbol    TBX20 [Similar Products]
 NCBI Official Synonym Symbols   
ASD4
[Similar Products]
 NCBI Protein Information    T-box transcription factor TBX20; T-box protein 20
 UniProt Protein Name    T-box transcription factor TBX20
 Protein Family    T-box transcription factor
 UniProt Gene Name    TBX20 [Similar Products]
 UniProt Synonym Gene Names    T-box protein 20 [Similar Products]
 UniProt Entry Name    TBX20_HUMAN
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 NCBI Summary for TBX20    This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
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 UniProt Comments for TBX20    TBX20: Probable transcriptional regulator involved in developmental processes. Defects in TBX20 are the cause of atrial septal defect type 4 (ASD4). ASD4 is a congenital heart malformation characterized by incomplete closure of the wall between the atria resulting in blood flow from the left to the right atria. ASD4 patients show other heart abnormalities including defects in septation, chamber growth and valvulogenesis. ASD4 is not associated with defects in the cardiac conduction system or with non-cardiac abnormalities.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 7p14.3

Cellular Component: cytoplasm; nucleus

Molecular Function: transcription factor activity

Biological Process: transcription, DNA-dependent; blood circulation; lateral mesoderm formation; neuron migration; negative regulation of transcription from RNA polymerase II promoter; patterning of blood vessels; cell proliferation; visceral motor neuron differentiation; muscle contraction; dorsal/ventral pattern formation; endoderm formation; cardiac muscle morphogensis; positive regulation of transcription from RNA polymerase II promoter; heart looping; negative regulation of transcription, DNA-dependent; positive regulation of cardiac muscle cell proliferation

Disease: Atrial Septal Defect 4
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 Research Articles on TBX20    1. Tbx20 regulated PPAR-gamma expression and protected the vascular endothelial cells from oxidized low-density lipoprotein -induced injury.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TBX20 recombinant proteinPathways associated with TBX20 recombinant protein
 Reference Product  PubMed Publications
 NKX2-5 recombinant protein  >19 publications with TBX20 and NKX2-5
 GATA4 recombinant protein  >16 publications with TBX20 and GATA4
 ISL1 recombinant protein  >4 publications with TBX20 and ISL1
 BMP10 recombinant protein  >3 publications with TBX20 and BMP10
 GATA5 recombinant protein  >3 publications with TBX20 and GATA5
 GATA6 recombinant protein  >1 publications with TBX20 and GATA6
 Products by Pathway  Pathway Diagram
 Cardiac Progenitor Differentiation Pathway antibodies  Cardiac Progenitor Differentiation Pathway Diagram
 Heart Development Pathway antibodies  Heart Development Pathway Diagram
Diseases associated with TBX20 recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >31 publications with TBX20 and Cardiovascular Diseases
 Heart Defects, Congenital Antibodies  >31 publications with TBX20 and Heart Defects, Congenital
 Congenital Abnormalities Antibodies  >21 publications with TBX20 and Congenital Abnormalities
 Inflammation Antibodies  >2 publications with TBX20 and Inflammation
 Fetal Growth Retardation Antibodies  >1 publications with TBX20 and Fetal Growth Retardation
 Fetal Death Antibodies  >1 publications with TBX20 and Fetal Death
 Lung Diseases Antibodies  >1 publications with TBX20 and Lung Diseases
 Atrophy Antibodies  >1 publications with TBX20 and Atrophy
 Respiratory Tract Diseases Antibodies  >1 publications with TBX20 and Respiratory Tract Diseases
 Weight Loss Antibodies  >1 publications with TBX20 and Weight Loss
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