Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow TAF15  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • p44-42 MAP Kinase (Phospho-Thr202) Antibody
 • ELF1 Antibody
 • ARSI Antibody
 • Cytochrome P450 2D6 (CYP2D6) Antibody
 • Red Cell Antibody (ARCA) ELISA Kit
 • Immunoglobulin G4 (IgG4) ELISA Kit
 • Oj Autoantibody (OJ-LLERS) ELISA Kit
 • Growth Factor Receptor Bound Protein 14 (GRB14) ELISA Kit
 • Glucose Oxidase (GOD) ELISA Kit
 • Plasminogen Activator Inhibitor 1 (PAI 1) ELISA Kit
 • Soluble Interleukin 2A Receptor (IL-2SRA) ELISA Kit
 • Immune Ribonucleic Acid-Immune Rna (IRNA) ELISA Kit
 • Interleukin 1beta Converting Enzyme (ICE) ELISA Kit
 • Nuclear Factor Kb P65 (NFKB P65) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

TAF15 recombinant protein

Scan QR to view Datasheet Catalog #    MBS204867
SDS-PAGE
Unit / Price
0.1 mg  /  $375 +1 FREE 8GB USB
0.5 mg  /  $925 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TAF15, Recombinant Protein

 Also Known As   

TAF15, 148-406aa, Human, His tag, E Coli

 Product Synonym Names    TATA-binding protein-associated factor 2N isoform 1; Npl3; RBP56; TAF2N; TAFII68
 Product Gene Name   

TAF15 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    MGSSHHHHHH SSGLVPRGSH MGSSYHSQRE NYSHHTQDDR RDVSRYGEDN RGYGGSQGGG RGRGGYDKDG RGPMTGSSGG DRGGFKNFGG HRDYGPRTDA DSESDNSDNN TIFVQGLGEG VSTDQVGEFF KQIGIIKTNK KTGKPMINLY TDKDTGKPKG EATVSFDDPP SAKAAIDWFD GKEFHGNIIK VSFATRRPEF MRGGGSGGGR RGRGGYRGRG GFQGRGGDPK SGDWVCPNPS CGNMNFARRN SCNQCNEPRP EDSRPSGGDF RGRGYGGERG YR
Section Bar
Section Bar
 Purity/Purification    > 90% by SDS - PAGE
 Form/Format    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
 Concentration    0.25 mg/ml (determined by Bradford assay) (lot specific)
Section Bar
 Antigen Species    Human
 Tag    His-tag
 Expression System    E Coli
Section Bar
 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of TAF15 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for TAF15 recombinant protein

   TAF15 is a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Recombinant human TAF15 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
 Product Categories/Family for TAF15 recombinant protein    Epigenomics (Transcription & Translation)
 Applications Tested/Suitable for TAF15 recombinant protein   

SDS-PAGE

Section Bar
 SDS-PAGE of TAF15 recombinant protein    TAF15 recombinant protein SDS-PAGE image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for TAF15. It may not necessarily be applicable to this product.
 NCBI GI #    21327701
 NCBI GeneID    8148
 NCBI Accession #    NP_631961 [Other Products]
 NCBI GenBank Nucleotide #    NM_139215.2 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q86X94; Q92751; B2R837 [Other Products]
 UniProt Related Accession #    Q92804 [Other Products]
 Molecular Weight    30kDa (282aa), confirmed by MALDI-TOF
Table BarTOPTable Bar
 NCBI Official Full Name    TATA-binding protein-associated factor 2N isoform 1
 NCBI Official Synonym Full Names    TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
 NCBI Official Symbol    TAF15 [Similar Products]
 NCBI Official Synonym Symbols   
Npl3; RBP56; TAF2N; TAFII68
[Similar Products]
 NCBI Protein Information    TATA-binding protein-associated factor 2N; RBP56/CSMF fusion; TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56); TATA box-binding protein-associated factor 2N (RNA-binding protein 56); TBP-associated factor 15
 UniProt Protein Name    TATA-binding protein-associated factor 2N
 UniProt Synonym Protein Names   
68 kDa TATA-binding protein-associated factor; TAF(II)68; TAFII68; RNA-binding protein 56
 Protein Family    Transcription initiation factor
 UniProt Gene Name    TAF15 [Similar Products]
 UniProt Synonym Gene Names    RBP56; TAF2N; TAF(II)68; TAFII68 [Similar Products]
 UniProt Entry Name    RBP56_HUMAN
Section Bar
 NCBI Summary for TAF15    This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Section Bar
 UniProt Comments for TAF15    TAF15: RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II). A chromosomal aberration involving TAF15/TAF2N is found in a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with NR4A3. Belongs to the RRM TET family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Translation; RNA-binding; Oncoprotein

Chromosomal Location of Human Ortholog: 17q11.1-q11.2

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus

Molecular Function: protein binding; DNA binding; zinc ion binding; nucleotide binding

Biological Process: positive regulation of transcription, DNA-dependent

Disease: Chondrosarcoma, Extraskeletal Myxoid
Table BarTOPTable Bar
 

Product References and Citations for TAF15 recombinant protein

   Martini A, La Starza R, et al. (2002). Cancer Res. 62(19):5408-12.
Section Bar
 Research Articles on TAF15    1. our data suggest that TAF15 and TLS/FUS operate within similar but not identical hnRNP M-TET protein complexes to influence the transcriptional or post-transcriptional output of a particular cell type.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with TAF15 recombinant proteinPathways associated with TAF15 recombinant protein
 Reference Product  PubMed Publications
 NR4A3 recombinant protein  >12 publications with TAF15 and NR4A3
 TBP recombinant protein  >7 publications with TAF15 and TBP
 ZNF384 recombinant protein  >6 publications with TAF15 and ZNF384
 TCF12 recombinant protein  >3 publications with TAF15 and TCF12
 PRMT1 recombinant protein  >1 publications with TAF15 and PRMT1
 Products by Pathway  Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
Diseases associated with TAF15 recombinant proteinOrgans/Tissues associated with TAF15 recombinant protein
 Disease Name  Pubmed Publications
 Osteosarcoma Antibodies  >5 publications with TAF15 and Osteosarcoma
 Chondrosarcoma, Extraskeletal Myxoid Antibodies  >4 publications with TAF15 and Chondrosarcoma, Extraskeletal Myxoid
 Immune System Diseases Antibodies  >3 publications with TAF15 and Immune System Diseases
 Lung Neoplasms Antibodies  >2 publications with TAF15 and Lung Neoplasms
 Cell Transformation, Neoplastic Antibodies  >2 publications with TAF15 and Cell Transformation, Neoplastic
 Disease Models, Animal Antibodies  >1 publications with TAF15 and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >1 publications with TAF15 and Neoplasms, Experimental
 Carcinoma Antibodies  >1 publications with TAF15 and Carcinoma
 Disease Progression Antibodies  >1 publications with TAF15 and Disease Progression
 Fibrosis Antibodies  >1 publications with TAF15 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Thyroid Antibodies  >9 publications with TAF15 and Thyroid
 Brain Antibodies  >9 publications with TAF15 and Brain
 Connective Tissue Antibodies  >4 publications with TAF15 and Connective Tissue
 Muscle Antibodies  >3 publications with TAF15 and Muscle
 Vascular Antibodies  >2 publications with TAF15 and Vascular
 Lung Antibodies  >2 publications with TAF15 and Lung
 Blood Antibodies  >1 publications with TAF15 and Blood
 Eye Antibodies  >1 publications with TAF15 and Eye
 Embryonic Tissue Antibodies  >1 publications with TAF15 and Embryonic Tissue
 Stomach Antibodies  >1 publications with TAF15 and Stomach
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions