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TCTP recombinant protein

Scan QR to view Datasheet Catalog #    MBS203422
SDS-Page
Unit / Price
0.1 mg  /  $285 +1 FREE 8GB USB
0.5 mg  /  $640 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TCTP, Recombinant Protein

★Popular Item★
 Also Known As   

TCTP, 1-172aa, Human, His tag, E Coli

 Product Synonym Names    TPT1; HRF; p02; Fortilin; Histamine releasing factor; P23; Tumor protein translationally controlled 1.
 Product Gene Name   

TCTP recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMMI IYRDLISHDE MFSDIYKIRE IADGLCLEVE GKMVSRTEGN IDDSLIGGNA SAEGPEGEGT ESTVITGVDI VMNHHLQETS FTKEAYKKYI KDYMKSIKGK LEEQRPERVK PFMTGAAEQI KHILANFKNY QFFIGENMNP DGMVALLDYR EDGVTPYMIF FKDGLEMEKC
 OMIM    X16064 mRNA
 3D Structure    ModBase 3D Structure for P13693
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 Host    E Coli
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 Purity/Purification    > 90% by SDS-PAGE
 Form/Format    Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol 0.1M NaCl
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag Information    His-tag
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of TCTP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for TCTP recombinant protein

   TCTP, also known as Translationally controlled tumor protein, is regulated at the translational level. This protein is involved in calcium binding and microtubule stabilization. It is an immunoglobulin E dependent histamine-releasing factor produced by lymphocytes of atopic children and present in biologic fluids of allergic patients. Recombinant TCTP protein was expressed in E Coli and purified by using conventional chromatography techniques.
 Product Categories/Family for TCTP recombinant protein    Immunology
 Applications Tested/Suitable for TCTP recombinant protein   

SDS-PAGE

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 SDS-Page of TCTP recombinant protein    TCTP recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for TCTP. It may not necessarily be applicable to this product.
 NCBI GI #    4507669
 NCBI GeneID    7178
 NCBI Accession #    NP_003286 [Other Products]
 NCBI GenBank Nucleotide #    NM_003295.3 [Other Products]
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 UniProt Primary Accession #    P13693 [Other Products]
 UniProt Secondary Accession #    Q6YLS2; Q7Z4J4; Q8TBK7; Q96EE2; Q9UC70; B2R7E5 [Other Products]
 UniProt Related Accession #    P13693 [Other Products]
 Molecular Weight    23.9 kDa (210aa), confirmed by MALDI-TOF.
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 NCBI Official Full Name    translationally-controlled tumor protein isoform 2
 NCBI Official Synonym Full Names    tumor protein, translationally-controlled 1
 NCBI Official Symbol    TPT1 [Similar Products]
 NCBI Official Synonym Symbols   
HRF; p02; p23; TCTP
[Similar Products]
 NCBI Protein Information    translationally-controlled tumor protein
 UniProt Protein Name    Translationally-controlled tumor protein
 UniProt Synonym Protein Names   
Fortilin; Histamine-releasing factor; HRF; p23
 UniProt Gene Name    TPT1 [Similar Products]
 UniProt Synonym Gene Names    TCTP; HRF [Similar Products]
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 NCBI Summary for TCTP    This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
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 UniProt Comments for TCTP    Involved in calcium binding and microtubule stabilization.
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Product References and Citations for TCTP recombinant protein

   Sanchez JC., et al. (1997) Electrophoresis. 18 (1):150-5.; Vonakis BM., et al. (2008) Blood. 111 (4):1789-96.
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 Research Articles on TCTP    1. The structure of human HRF (hHRF) was solved in 2 new crystal forms, one at the highest resolution (1.4A) yet reported. The high resolution hHRF structure reveals a disulphide-linked dimer, in which the 2 molecules are closely associated and provides a model for the role of HRF in mast cell activation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with TCTP recombinant proteinDiseases associated with TCTP recombinant protein
 Products by Pathway  Pathway Diagram
 PLK1 Signaling Events Pathway antibodies  PLK1 Signaling Events Pathway Diagram
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >4 publications with TCTP and Liver Diseases
 Neoplasms, Experimental Antibodies  >4 publications with TCTP and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >4 publications with TCTP and Breast Neoplasms
 Liver Neoplasms Antibodies  >3 publications with TCTP and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >3 publications with TCTP and Carcinoma, Hepatocellular
 Cell Transformation, Neoplastic Antibodies  >2 publications with TCTP and Cell Transformation, Neoplastic
 Heart Diseases Antibodies  >2 publications with TCTP and Heart Diseases
 Lung Diseases Antibodies  >2 publications with TCTP and Lung Diseases
 Disease Models, Animal Antibodies  >2 publications with TCTP and Disease Models, Animal
 Neoplasm Invasiveness Antibodies  >1 publications with TCTP and Neoplasm Invasiveness
Organs/Tissues associated with TCTP recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >6 publications with TCTP and Liver
 Skin Antibodies  >6 publications with TCTP and Skin
 Heart Antibodies  >6 publications with TCTP and Heart
 Blood Antibodies  >5 publications with TCTP and Blood
 Bone Antibodies  >4 publications with TCTP and Bone
 Lung Antibodies  >3 publications with TCTP and Lung
 Muscle Antibodies  >3 publications with TCTP and Muscle
 Brain Antibodies  >3 publications with TCTP and Brain
 Testis Antibodies  >2 publications with TCTP and Testis
 Intestine Antibodies  >2 publications with TCTP and Intestine
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