NP_443096
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
24.0 kDa (208aa) confirmed by MALDI-TOF
NCBI Official Full Name
TRAF-interacting protein with FHA domain-containing protein A
NCBI Official Synonym Full Names
TRAF interacting protein with forkhead associated domain
NCBI Protein Information
TRAF-interacting protein with FHA domain-containing protein A
UniProt Protein Name
TRAF-interacting protein with FHA domain-containing protein A
UniProt Synonym Protein Names
Putative MAPK-activating protein PM14; Putative NF-kappa-B-activating protein 20; TRAF2-binding protein
UniProt Synonym Gene Names
UniProt Comments for TIFA
Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.
Product References and Citations for TIFA recombinant protein
Takatsuna H., et al. (2003) J. Biol. Chem. 278:12144-12150; Ea C.-K., et al. (2004) Proc. Natl. Acad. Sci. u.S.A. 101:15318-15323
Research Articles on TIFA
Precautions
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Disclaimer
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Products associated with TIFA recombinant protein
Pathways associated with TIFA recombinant protein
Diseases associated with TIFA recombinant protein
Organs/Tissues associated with TIFA recombinant protein
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