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TNFRSF13B recombinant protein

Scan QR to view Datasheet Catalog #    MBS204899
SDS-Page
Unit / Price
0.1 mg  /  $310 +1 FREE 8GB USB
0.5 mg  /  $720 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TNFRSF13B, Recombinant Protein

★Popular Item★
 Also Known As   

TNFRSF13B, 1-165aa, Human, His tag, E Coli (Denatured)

 Product Synonym Names    Tumor necrosis factor receptor superfamily member 13B; CD267; CVID; CVID2; TACI; TNFRSF14B
 Product Gene Name   

TNFRSF13B recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHHHHH SSGLVPRGSH MGSMSGLGRS RRGGRSRVDQ EERFPQGLWT GVAMRSCPEE QYWDPLLGTC MSCKTICNHQ SQRTCAAFCR SLSCRKEQGK FYDHLLRDCI SCASICGQHP KQCAYFCENK LRSPVNLPPE LRRQRSGEVE NNSDNSGRYQ GLEHRGSEAS PALPGLKLSA DQVALVYS
 OMIM    AF023614 mRNA
 3D Structure    ModBase 3D Structure for O14836
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 Host    E Coli
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 Purity/Purification    > 90% by SDS-PAGE
 Form/Format    Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol 0.4M urea
 Concentration    1 mg/ml (determined by Bradford assay) (lot specific)
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 Antigen Species    Human
 Tag Information    His-tag
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 Preparation and Storage    Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of TNFRSF13B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for TNFRSF13B recombinant protein

   TNFRSF13B, also known as TACI, is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system. It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). It was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family. It controls T cell-independent B cell antibody responses, isotype switching, and B cell homeostasis. Recombinant human TNFRSF13B protein, fused to His-tag at N-terminus, was expressed in E Coli.
 Product Categories/Family for TNFRSF13B recombinant protein    Immunology
 Applications Tested/Suitable for TNFRSF13B recombinant protein   

SDS-PAGE

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 SDS-Page of TNFRSF13B recombinant protein    TNFRSF13B recombinant protein SDS-Page image
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NCBI/Uniprot data below describe general gene information for TNFRSF13B. It may not necessarily be applicable to this product.
 NCBI GI #    6912694
 NCBI GeneID    23495
 NCBI Accession #    NP_036584 [Other Products]
 NCBI GenBank Nucleotide #    NM_012452.2 [Other Products]
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 UniProt Primary Accession #    O14836 [Other Products]
 UniProt Secondary Accession #    Q32LX4; Q7Z6F5; B2R8B0; B7Z6V8 [Other Products]
 UniProt Related Accession #    O14836 [Other Products]
 Molecular Weight    20.9 kDa (188aa)
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 NCBI Official Full Name    tumor necrosis factor receptor superfamily member 13B
 NCBI Official Synonym Full Names    TNF receptor superfamily member 13B
 NCBI Official Symbol    TNFRSF13B [Similar Products]
 NCBI Official Synonym Symbols   
CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B
[Similar Products]
 NCBI Protein Information    tumor necrosis factor receptor superfamily member 13B
 UniProt Protein Name    Tumor necrosis factor receptor superfamily member 13B
 UniProt Synonym Protein Names   
Transmembrane activator and CAML interactor; CD_antigen: CD267
 Protein Family    Tumor necrosis factor receptor superfamily
 UniProt Gene Name    TNFRSF13B [Similar Products]
 UniProt Synonym Gene Names    TACI [Similar Products]
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 NCBI Summary for TNFRSF13B    The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TNFRSF13B    Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.
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Product References and Citations for TNFRSF13B recombinant protein

   Wu Y. et al. (2000) J Biol Chem. 275:35478-35485.; von Bulow Gu. et al. (1997) Science. 278:138-141.;
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 Research Articles on TNFRSF13B    1. BAFF-induced processing of BAFFR regulates BAFF-mediated B cell responses in a TACI-dependent manner.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TNFRSF13B recombinant proteinPathways associated with TNFRSF13B recombinant protein
 Reference Product  PubMed Publications
 TNFSF13B recombinant protein  >99 publications with TNFRSF13B and TNFSF13B
 TNFRSF17 recombinant protein  >85 publications with TNFRSF13B and TNFRSF17
 TNFRSF13C recombinant protein  >71 publications with TNFRSF13B and TNFRSF13C
 TRAF2 recombinant protein  >4 publications with TNFRSF13B and TRAF2
 CAMLG recombinant protein  >3 publications with TNFRSF13B and CAMLG
 SDC2 recombinant protein  >2 publications with TNFRSF13B and SDC2
 SDC4 recombinant protein  >1 publications with TNFRSF13B and SDC4
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Primary Immunodeficiency Pathway antibodies  Primary Immunodeficiency Pathway Diagram
 Primary Immunodeficiency Pathway antibodies  Primary Immunodeficiency Pathway Diagram
 Syndecan-2-mediated Signaling Events Pathway antibodies  Syndecan-2-mediated Signaling Events Pathway Diagram
 Syndecan-4-mediated Signaling Events Pathway antibodies  Syndecan-4-mediated Signaling Events Pathway Diagram
Diseases associated with TNFRSF13B recombinant proteinOrgans/Tissues associated with TNFRSF13B recombinant protein
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >161 publications with TNFRSF13B and Necrosis
 Immune System Diseases Antibodies  >153 publications with TNFRSF13B and Immune System Diseases
 Common Variable Immunodeficiency Antibodies  >76 publications with TNFRSF13B and Common Variable Immunodeficiency
 Immunologic Deficiency Syndromes Antibodies  >71 publications with TNFRSF13B and Immunologic Deficiency Syndromes
 Inflammation Antibodies  >18 publications with TNFRSF13B and Inflammation
 Multiple Myeloma Antibodies  >14 publications with TNFRSF13B and Multiple Myeloma
 Congenital, Hereditary, and Neonatal Diseases and Abnormalities Antibodies  >10 publications with TNFRSF13B and Congenital, Hereditary, and Neonatal Diseases and Abnormalities
 Immunoglobulin a deficiency 2 Antibodies  >5 publications with TNFRSF13B and Immunoglobulin a deficiency 2
 Kidney Diseases Antibodies  >5 publications with TNFRSF13B and Kidney Diseases
 Hyperplasia Antibodies  >4 publications with TNFRSF13B and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >193 publications with TNFRSF13B and Blood
 Spleen Antibodies  >21 publications with TNFRSF13B and Spleen
 Lymph Antibodies  >6 publications with TNFRSF13B and Lymph
 Intestine Antibodies  >2 publications with TNFRSF13B and Intestine
 Mixed Antibodies  >1 publications with TNFRSF13B and Mixed
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