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THBS1 recombinant protein :: Thrombospondin-1 (THBS1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1265467 (PROMOTIONAL PRICING: 10% OFF web price. Discount is not applicable for bulk pricing such as 5x96T or 10x96T. Discount will be applied after order has been placed)
SDS-Page
Unit / Price
0.05 mg (E-Coli)  /  $175 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $295 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $580 +1 FREE 8GB USB
1 mg (E-Coli)  /  $855 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $950 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,170 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,170 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,400 +1 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,860 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,860 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,860 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,760 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Thrombospondin-1 (THBS1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Thrombospondin-1 (THBS1) , partial

 Product Gene Name   

THBS1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    19-350, Partial, include the Laminin G-like domain
 Sequence    NRIPESGGDN SVFDIFELTG AARKGSGRRL VKGPDPSSPA FRIEDANLIP PVPDDKFQDL VDAVRAEKGF LLLASLRQMK KTRGTLLALE RKDHSGQVFS VVSNGKAGTL DLSLTVQGKQ HVVSVEEALL ATGQWKSITL FVQEDRAQLY IDCEKMENAE LDVPIQSVFT RDLASIARLR IAKGGVNDNF QGVLQNVRFV FGTTPEDILR NKGCSSSTSV LLTLDNNVVN GSSPAIRTNY IGHKTKDLQA ICGISCDELS SMVLELRGLR TIVTTLQDSI RKVTEENKEL ANELRRPPLC YHNGVQYRNN EEWTVDSCTE CHCQNSVTIC KK
 OMIM    188060
 3D Structure    ModBase 3D Structure for P07996
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of THBS1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for THBS1 recombinant protein

   This protein is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V
beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.
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 SDS-Page of THBS1 recombinant protein    THBS1 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for THBS1. It may not necessarily be applicable to this product.
 NCBI GI #    40317626
 NCBI GeneID    7057
 NCBI Accession #    NP_003237.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003246.3 [Other Products]
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 UniProt Primary Accession #    P07996 [Other Products]
 UniProt Secondary Accession #    Q15667; Q59E99; A8K6H4; B4E3J7; B9EGH6 [Other Products]
 UniProt Related Accession #    P07996 [Other Products]
 Molecular Weight    120,148 Da
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 NCBI Official Full Name    thrombospondin-1
 NCBI Official Synonym Full Names    thrombospondin 1
 NCBI Official Symbol    THBS1 [Similar Products]
 NCBI Official Synonym Symbols   
TSP; THBS; TSP1; TSP-1; THBS-1
[Similar Products]
 NCBI Protein Information    thrombospondin-1
 UniProt Protein Name    Thrombospondin-1
 Protein Family    Thrombospondin
 UniProt Gene Name    THBS1 [Similar Products]
 UniProt Synonym Gene Names    TSP; TSP1 [Similar Products]
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 NCBI Summary for THBS1    The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]
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 UniProt Comments for THBS1    Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors ().
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 Research Articles on THBS1    1. Studies show that thrombospondin-1 (Thbs-1), is a prolific contributor to the production and modulation of ROS in large conductance vessels and in the peripheral circulation. Recently, the presence of physiologically relevant circulating Thbs-1 levels was proven to also disrupt vasodilation to nitric oxide (NO) in coronary arterioles from aged animals, negatively impacting coronary blood flow reserve. [review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with THBS1 recombinant proteinPathways associated with THBS1 recombinant protein
 Reference Product  PubMed Publications
 CD36 recombinant protein  >192 publications with THBS1 and CD36
 CD47 recombinant protein  >157 publications with THBS1 and CD47
 FGF2 recombinant protein  >107 publications with THBS1 and FGF2
 VEGFA recombinant protein  >67 publications with THBS1 and VEGFA
 COL18A1 recombinant protein  >47 publications with THBS1 and COL18A1
 MMP9 recombinant protein  >26 publications with THBS1 and MMP9
 MMP2 recombinant protein  >18 publications with THBS1 and MMP2
 LRP1 recombinant protein  >12 publications with THBS1 and LRP1
 ITGB3 recombinant protein  >5 publications with THBS1 and ITGB3
 Products by Pathway  Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Inflammatory Response Pathway antibodies  Inflammatory Response Pathway Diagram
Diseases associated with THBS1 recombinant proteinOrgans/Tissues associated with THBS1 recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >249 publications with THBS1 and Cardiovascular Diseases
 Inflammation Antibodies  >239 publications with THBS1 and Inflammation
 Disease Models, Animal Antibodies  >215 publications with THBS1 and Disease Models, Animal
 Fibrosis Antibodies  >152 publications with THBS1 and Fibrosis
 Breast Neoplasms Antibodies  >125 publications with THBS1 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >123 publications with THBS1 and Neoplasms, Experimental
 Neoplasm Metastasis Antibodies  >115 publications with THBS1 and Neoplasm Metastasis
 Necrosis Antibodies  >105 publications with THBS1 and Necrosis
 Kidney Diseases Antibodies  >96 publications with THBS1 and Kidney Diseases
 Heart Diseases Antibodies  >89 publications with THBS1 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >1013 publications with THBS1 and Vascular
 Blood Antibodies  >980 publications with THBS1 and Blood
 Muscle Antibodies  >280 publications with THBS1 and Muscle
 Eye Antibodies  >170 publications with THBS1 and Eye
 Kidney Antibodies  >168 publications with THBS1 and Kidney
 Lung Antibodies  >165 publications with THBS1 and Lung
 Brain Antibodies  >157 publications with THBS1 and Brain
 Bone Antibodies  >145 publications with THBS1 and Bone
 Heart Antibodies  >135 publications with THBS1 and Heart
 Skin Antibodies  >127 publications with THBS1 and Skin
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