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Tg recombinant protein :: Thyroglobulin (Tg) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1258460 Tg recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $1,035 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,035 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,265 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,265 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,575 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,575 +1 FREE 8GB USB
1 mg (Yeast)  /  $2,035 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,035 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Thyroglobulin (Tg), Recombinant Protein

 Also Known As   

Recombinant Mouse Thyroglobulin (Tg) , partial

 Product Gene Name   

Tg recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    21-300; Fragment at the N-terminal;
 Sequence    NIFEYQVDAQ PLRPCELQRE KAFLKQAEYV PQCSEDGSFQ TVQCQNDGQS CWCVDSDGRE VPGSRQLGRP TVCLSFCQLH KQRILLGSYI NSTDALYLPQ CQDSGNYAPV QCDLQRVQCW CVDTEGMEVY GTRQQGRPTR CPRSCEIRNR RLLHGVGDRS PPQCTADGEF MPVQCKFVNT TDMMIFDLIH NYNRFPDAFV TFSSFRGRFP EVSGYCYCAD SQGRELAETG LELLLDEIYD TIFAGLDQAS TFTQSTMYRI LQRRFLAIQL VISGRFRCPT
 3D Structure    ModBase 3D Structure for O08710
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Tg recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Tg recombinant protein

   Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.
NCBI/Uniprot data below describe general gene information for Tg. It may not necessarily be applicable to this product.
 NCBI GI #    124430576
 NCBI GeneID    21819
 NCBI Accession #    NP_033401.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_009375.2 [Other Products]
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 UniProt Primary Accession #    O08710 [Other Products]
 UniProt Secondary Accession #    O88590; Q2NKY1; Q9QWY7 [Other Products]
 UniProt Related Accession #    O08710 [Other Products]
 Molecular Weight    304,473 Da
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 NCBI Official Full Name    thyroglobulin
 NCBI Official Synonym Full Names    thyroglobulin
 NCBI Official Symbol    Tg [Similar Products]
 NCBI Official Synonym Symbols   
Tgn; cog
[Similar Products]
 NCBI Protein Information    thyroglobulin
 UniProt Protein Name    Thyroglobulin
 Protein Family    Thyroglobulin
 UniProt Gene Name    Tg [Similar Products]
 UniProt Synonym Gene Names    Tgn; Tg [Similar Products]
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 UniProt Comments for Tg    Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3).
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 Research Articles on Tg    1. Findings suggest that coumestrol treatment may have some beneficial actions against thyroid-specific thyroglobulin (Tg) autoantibody production in the development of autoimmune thyroiditis through suppression of Th1 response.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Tg recombinant proteinPathways associated with Tg recombinant protein
 Reference Product  PubMed Publications
 Tpo recombinant protein  >722 publications with Tg and Tpo
 Nkx2-1 recombinant protein  >25 publications with Tg and Nkx2-1
 Ins2 recombinant protein  >11 publications with Tg and Ins2
 Ins1 recombinant protein  >6 publications with Tg and Ins1
 Pdia3 recombinant protein  >5 publications with Tg and Pdia3
 Lrp2 recombinant protein  >4 publications with Tg and Lrp2
 Hhex recombinant protein  >3 publications with Tg and Hhex
 Products by Pathway  Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Thyroid Hormone Synthesis Pathway antibodies  Thyroid Hormone Synthesis Pathway Diagram
 Thyroid Hormone Synthesis Pathway antibodies  Thyroid Hormone Synthesis Pathway Diagram
Diseases associated with Tg recombinant proteinOrgans/Tissues associated with Tg recombinant protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >5499 publications with Tg and Cardiovascular Diseases
 Dyslipidemias Antibodies  >3471 publications with Tg and Dyslipidemias
 Thyroid Diseases Antibodies  >2670 publications with Tg and Thyroid Diseases
 Heart Diseases Antibodies  >2418 publications with Tg and Heart Diseases
 Fatty Liver Antibodies  >2102 publications with Tg and Fatty Liver
 Inflammation Antibodies  >1978 publications with Tg and Inflammation
 Liver Diseases Antibodies  >1858 publications with Tg and Liver Diseases
 Hypertension Antibodies  >1631 publications with Tg and Hypertension
 Thyroid Neoplasms Antibodies  >1352 publications with Tg and Thyroid Neoplasms
 Necrosis Antibodies  >1070 publications with Tg and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Thyroid Antibodies  >3516 publications with Tg and Thyroid
 Brain Antibodies  >2641 publications with Tg and Brain
 Skin Antibodies  >872 publications with Tg and Skin
 Thymus Antibodies  >382 publications with Tg and Thymus
 Embryonic Tissue Antibodies  >323 publications with Tg and Embryonic Tissue
 Pituitary Gland Antibodies  >109 publications with Tg and Pituitary Gland
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