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r-hTPO recombinant protein :: Thyroid Peroxidase Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS172020 r-hTPO recombinant protein
Unit / Price
0.01 mg  /  $200 +1 FREE 8GB USB
0.05 mg  /  $480 +1 FREE 8GB USB
0.5 mg  /  $2,350 +2 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Thyroid Peroxidase (r-hTPO), Recombinant Protein

 Also Known As   

Recombinant Thyroid Peroxidase (r-TPO)

 Product Synonym Names    Thyroid Peroxidase (TPO) - >=96% (SDS-PAGE)
 Product Gene Name   

r-hTPO recombinant protein

[Similar Products]
 Product Synonym Gene Name    r-TPO;TPO [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Purity/Purification    >= 96% (SDS-PAGE)
 Form/Format    Liquid
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 Source    Baculovirus, Sf9 Cells
 Recertification    2 years
 Protein    > 0.5 mg/mL
 pH    7.6
 Additional Info    Full-length protein, no tag sequences or membrane binding domain, and not enzymatically active
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 Preparation and Storage    At -20 degree C
 Other Notes    Small volumes of r-hTPO recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for r-hTPO recombinant protein

   Human Thyroid peroxidase (TPO) is an enzyme mainly expressed in the thyroid that liberates iodine for addition onto tyrosine residues on Thyroglobulin for the production of thyroxine (thyroid hormone).Thyroid Peroxidase is the antigenic determinant of the thyroid microsome associated with anti-TPO autoantibodies. Anti-TPO is an important secondary marker in the diagnosis of Grave's and Hashimoto disease. Thyroid antibodies are also assiciated with infertility and fetal loss.

Technical support, bulk quantities and aliquoting available.
 Product Categories/Family for r-hTPO recombinant protein    Recombinant; Proteins; Antigens; Standards/controls; Immunogen; Thyroid Peroxidase (tpo)
 Applications Tested/Suitable for r-hTPO recombinant protein   

Western Blot (WB)

 Application Notes for r-hTPO recombinant protein    Application: Autoimmune capture in commercial assays
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NCBI/Uniprot data below describe general gene information for r-hTPO. It may not necessarily be applicable to this product.
 NCBI GI #    4261820
 NCBI Accession #    AAD14120.1 [Other Products]
 Molecular Weight    ~104,000
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 NCBI Official Full Name    thyroid peroxidase, partial
 Protein Family    Thyroid peroxidase
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 NCBI Summary for r-hTPO    This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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