Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow TPO  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • MARK4 Antibody
 • Protectin (CD59) ELISA Kit
 • Thrombopoietin Receptor Antibody (TPOR) ELISA Kit
 • Complement Component 9 (C9) ELISA Kit
 • Cotinine ELISA Kit
 • Anterior Gradient Homolog 2 (AGR2) ELISA Kit
 • CytomegaloVirus IgM Antibody (AMW IgM) ELISA Kit
 • Neurotrophin-3 (NT-3) ELISA Kit
 • Deoxypyridinoline (DPD) ELISA Kit
 • Ubiquitin ELISA Kit
 • Matrix Metalloproteinase 28 (MMP-28) ELISA Kit
 • Voltage-Gated Calcium Channel (VGCC) ELISA Kit
 • Carboxypeptidase N2 (CPN2) ELISA Kit
 • Semaphorin 3E (SEMA3E) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

TPO recombinant protein :: Thyroid peroxidase Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS958565
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Thyroid peroxidase (TPO), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Rat Thyroid peroxidase

 Product Gene Name   

TPO recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 MBS958565 COA    COA PDF
 Sequence Positions    32-834aa; Extracellular Domain
 Sequence    GKTMTSHVIS VVETSQLLVD NAVYNTMKRN LKKRGVLSPA QLLSFSKLPE STSGAISRAA EIMETSIQVM KREQSQFSTD ALSADILATI ANLSGCLPFM LPPRCPDTCL ANKYRPITGV CNNRDHPRWG ASNTALARWL PPVYEDGFSQ PRGWNPNFLY HGFPLPPVRE VTRHLIQVSN EAVTEDDQYS DFLPVWGQYI DHDIALTPQS TSTAAFWGGV DCQLTCENQN PCFPIQLPSN SSRTTACLPF YRSSAACGTG DQGALFGNLS AANPRQQMNG LTSFLDASTV YGSSPGVEKQ LRNWSSSAGL LRVNTLHLDS GRAYLPFASA ACAPEPGAPH ANRTPCFLAG DGRASEVPAL AAVHTLWLRE HNRLATAFKA INTHWSANTA YQEARKVVGA LHQIITMRDY IPKILGPDAF RQYVGPYEGY NPTVNPTVSN VFSTAAFRFG HATVHPLVRR LNTDFQDHTE LPRLQLHDVF FRPWRLIQEG GLDPIVRGLL ARPAKLQVQE QLMNEELTER LFVLSNVGTL DLASLNLQRG RDHGLPGYNE WREFCGLSRL DTGAELNKAI ANRSMVNKIM ELYKHADNID VWLGGLAEKF LPGARTGPLF ACIIGKQMKA LRDGDRFWWE NSHVFTDAQR QELEKHSLPR VICDNTGLTR VPVDAFRIGK FPQDFESCEE IPSMDLRLWR ETFPQDDKCV FPEKVDNGNF VHCEESGKLV LVYSCFHGYK LQGQEQVTCT QNGWDSEPPV CKDVNECADL THPPCHSSAK CKNTKGSFQC VCTDPYMLGE DEKTCIDSGR LPR
 3D Structure    ModBase 3D Structure for P14650
Section Bar
 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
Section Bar
 Purity/Purification    Greater than 90% as determined by SDS-PAGE.
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
Section Bar
Section Bar
 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TPO recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TPO purchase    A key enzyme in the synthesis of both of the two thyroid hormones, thyroid peroxidase TPO oxidases dietary iodine into a bioavailable form. Much of our current understanding of human TPO and autoimmune thyroid disease has come from research of rodent cells (rat & mouse) detailed in free Pubmed resources. Use of our recombinant TPO protein in cell culture experiments with or without other growth factors will accelerate clin endocrinol metab studies. This quality product is purified with his-tag expression systems to 90% purity and characterized with SDS PAGE; ideal for use as antigen for antibody production, either mAb or polyclonal species. MyBiosource also supplies other recombinant proteins and related products, such as thrombopoietin, human TPO antibodies, or human thyroid ELISA kits. To order thyroid peroxidase recombinant protein, use our website worldwide, including USA, UK Ireland Israel Italy and Europe.
Table BarTOPTable Bar
 

Product Description specifically for TPO recombinant protein

   Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T3 and T4.
Section Bar
 SDS-PAGE of TPO recombinant protein    TPO recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for TPO. It may not necessarily be applicable to this product.
 NCBI GI #    129832
 NCBI GeneID    54314
 NCBI Accession #    P14650.1 [Other Products]
Section Bar
 UniProt Primary Accession #    P14650 [Other Products]
 UniProt Related Accession #    P14650 [Other Products]
 Molecular Weight    116.4KD
Table BarTOPTable Bar
 NCBI Official Full Name    Thyroid peroxidase
 NCBI Official Synonym Full Names    thyroid peroxidase
 NCBI Official Symbol    Tpo [Similar Products]
 NCBI Protein Information    thyroid peroxidase
 UniProt Protein Name    Thyroid peroxidase
 Protein Family    Thyroid peroxidase
 UniProt Gene Name    Tpo [Similar Products]
 UniProt Synonym Gene Names    TPO [Similar Products]
 UniProt Entry Name    PERT_RAT
Section Bar
 NCBI Summary for TPO    membrane-bound glycoprotein; iodinates tyrosine residues in thyroglobulin to generate biologically active thyroid hormones T3 and T4 [RGD, Feb 2006]
Section Bar
 UniProt Comments for TPO    Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T3 and T4.
Table BarTOPTable Bar
 

Product References and Citations for TPO recombinant protein

   Complete nucleotide sequence of the cDNA for thyroid peroxidase in FRTL5 rat thyroid cells.Derwahl M., Seto P., Rapoport B.Nucleic Acids Res. 17:8380-8380(1989) Thyroid peroxidase rat cDNA sequence, chromosomal localization in mouse, and regulation of gene expression by comparison to thyroglobulin in rat FRTL-5 cells.Isozaki O., Kohn L.D., Kozak C.A., Kimura S.Mol. Endocrinol. 3:1681-1692(1989)
Section Bar
 Research Articles on TPO    1. SREBP-1c and SREBP-2 are regulators of the rat thyroid peroxidase gene in thyroid cells
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with TPO recombinant proteinPathways associated with TPO recombinant protein
 Reference Product  PubMed Publications
 Tyr recombinant protein  >10 publications with TPO and Tyr
 Tat recombinant protein  >4 publications with TPO and Tat
 Iyd recombinant protein  >4 publications with TPO and Iyd
 Tshb recombinant protein  >2 publications with TPO and Tshb
 Products by Pathway  Pathway Diagram
 Amine-derived Hormones Pathway antibodies  Amine-derived Hormones Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Thyroid Hormone Biosynthesis, Tyrosine => Triiodothyronine/thyroxine Pathway antibodies  Thyroid Hormone Biosynthesis, Tyrosine => Triiodothyronine/thyroxine Pathway Diagram
 Thyroid Hormone Biosynthesis, Tyrosine => Triiodothyronine/thyroxine Pathway antibodies  Thyroid Hormone Biosynthesis, Tyrosine => Triiodothyronine/thyroxine Pathway Diagram
 Thyroid Hormone Synthesis Pathway antibodies  Thyroid Hormone Synthesis Pathway Diagram
 Thyroid Hormone Synthesis Pathway antibodies  Thyroid Hormone Synthesis Pathway Diagram
Organs/Tissues associated with TPO recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >75 publications with TPO and Mixed
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions