Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Recombinant Protein rightarrow TLR9  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • PCAF Antibody
 • SOMATOSTATIN (SST) Antibody
 • Gelsolin (Gsn) Recombinant Protein
 • Annexin A4 (ANXA4) ELISA Kit
 • Placental Lactogen ELISA Kit
 • Glucose 6 Phosphate Dehydrogenase (G6PD) ELISA Kit
 • RAD51L2 Antibody
 • Gliadin IgA ELISA Kit
 • 4-hydroxybenzoate polyprenyltransferase, mitochondrial (COQ2... ELISA Kit
 • Rabies Virus (RV) Antibody (IgG) ELISA Kit
 • DKK1 ELISA Kit
 • Glucocorticoid Receptor alpha (GRalpha) ELISA Kit
 • Anti-her2 ELISA Kit
 • SRPX Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

TLR9 recombinant protein :: Toll Like Receptor 9 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS2031580 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $140 +1 FREE 8GB USB
0.05 mg  /  $260 +1 FREE 8GB USB
0.1 mg  /  $400 +1 FREE 8GB USB
0.2 mg  /  $495 +1 FREE 8GB USB
0.5 mg  /  $955 +1 FREE 8GB USB
1 mg  /  $1,415 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Toll Like Receptor 9 (TLR9), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Toll Like Receptor 9 (TLR9)

 Product Gene Name   

TLR9 recombinant protein

[Similar Products]
 Matching Pairs    Antibody: Toll Like Receptor 9 (MBS2026432)
Antigen: Toll Like Receptor 9 (MBS2031580)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Host    E. coli
Section Bar
 Purity/Purification    > 97%
 Concentration    Original Concentration: 200 ug/mL (lot specific)
Section Bar
 Organism Species    Homo sapiens (Human)
 Source    Prokaryotic expression
 Residues    Thr28~Ser362
 Tags    N-terminal His Tag
 Subcellular Location    Lysosome, Cytoplasm, Endoplasmic reticulum lumen, Endosome
 Traits    Freeze-dried powder
 Buffer    20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT,0.01% SKL, 5% Trehalose and Proclin300.
 Predicted isoelectric point    9.1
 Predicted Molecular Mass    41.1kDa
 Accurate Molecular Mass    41kDa as determined by SDS-PAGE reducing conditions.
 USAGE    Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Section Bar
 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8C for one month.
Aliquot and store at -80C for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of TLR9 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for TLR9 recombinant protein   

Positive Control; Immunogen; SDS-PAGE; WB.

(May be suitable for use in other assays to be determined by the end user.)

Section Bar
 Sequence of TLR9 recombinant protein    TLR9 recombinant protein Sequence image
Section Bar
 Gene Sequence (extract) of TLR9 recombinant protein    TLR9 recombinant protein Gene Sequence (extract) image
Section Bar
 SDS-Page of TLR9 recombinant protein    TLR9 recombinant protein SDS-Page image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for TLR9. It may not necessarily be applicable to this product.
 NCBI GI #    157057166
 NCBI GeneID    81897
 NCBI Accession #    NP_112455.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_031178.2 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q4L0K3; Q4L0K4; Q99MF2; Q99MQ8; F8VPN5 [Other Products]
 UniProt Related Accession #    Q9EQU3 [Other Products]
Table BarTOPTable Bar
 NCBI Official Full Name    toll-like receptor 9
 NCBI Official Synonym Full Names    toll-like receptor 9
 NCBI Official Symbol    Tlr9 [Similar Products]
 NCBI Protein Information    toll-like receptor 9
 UniProt Protein Name    Toll-like receptor 9
 UniProt Synonym Protein Names   
CD_antigen: CD289
 Protein Family    Toll-like receptor
 UniProt Gene Name    Tlr9 [Similar Products]
 UniProt Entry Name    TLR9_MOUSE
Section Bar
 UniProt Comments for TLR9    TLR9: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection. Interacts with MYD88 via their respective TIR domains. Interacts (via transmembrane domain) with UNC93B1. Interacts with CD300LH; the interaction may promote full activation of TLR9-triggered innate responses. Interacts with BTK. Interacts with CNPY3 and HSP90B1; this interaction is required for proper folding in the endoplasmic reticulum. Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre- dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver. Belongs to the Toll-like receptor family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: membrane; basolateral plasma membrane; endoplasmic reticulum; lysosome; cytoplasm; apical plasma membrane; plasma membrane; integral to membrane; cytoplasmic vesicle; endosome

Molecular Function: protein binding; transmembrane receptor activity; siRNA binding; interleukin-1 receptor binding; unmethylated CpG binding

Biological Process: positive regulation of JNK activity; regulation of cytokine secretion; positive regulation of interleukin-12 production; maintenance of gastrointestinal epithelium; microglial cell activation; positive regulation of interferon-alpha biosynthetic process; regulation of B cell activation; positive regulation of NF-kappaB import into nucleus; signal transduction; positive regulation of interleukin-18 production; defense response to Gram-negative bacterium; positive regulation of interleukin-10 production; activation of NF-kappaB transcription factor; positive regulation of interleukin-8 production; response to molecule of bacterial origin; positive regulation of interferon-beta production; negative regulation of interleukin-8 production; negative regulation of interleukin-6 production; inflammatory response; defense response to virus; positive regulation of autophagy; regulation of protein amino acid phosphorylation; positive regulation of I-kappaB kinase/NF-kappaB cascade; immune system process; response to virus; positive regulation of interleukin-6 production; positive regulation of tumor necrosis factor production; positive regulation of toll-like receptor signaling pathway; positive regulation of chemokine production; MyD88-dependent toll-like receptor signaling pathway; inhibition of NF-kappaB transcription factor; regulation of inflammatory response; positive regulation of interferon-beta biosynthetic process; negative regulation of toll-like receptor signaling pathway; toll-like receptor signaling pathway; innate immune response; immune response; positive regulation of transcription from RNA polymerase II promoter; toll-like receptor 9 signaling pathway; I-kappaB phosphorylation; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of inflammatory response; positive regulation of interferon-gamma biosynthetic process
Table BarTOPTable Bar
 Research Articles on TLR9    1. B cell TLR1/2, TLR4, TLR7 and TLR9 interact in induction of class switch DNA recombination, modulated by BCR and CD40 in mounting of T-cell independent antibody responses.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with TLR9 recombinant proteinPathways associated with TLR9 recombinant protein
 Reference Product  PubMed Publications
 Tlr7 recombinant protein  >780 publications with TLR9 and Tlr7
 Tlr3 recombinant protein  >602 publications with TLR9 and Tlr3
 Myd88 recombinant protein  >494 publications with TLR9 and Myd88
 Tlr8 recombinant protein  >242 publications with TLR9 and Tlr8
 Cd40 recombinant protein  >170 publications with TLR9 and Cd40
 Unc93b1 recombinant protein  >43 publications with TLR9 and Unc93b1
 Hsp90b1 recombinant protein  >2 publications with TLR9 and Hsp90b1
 Eea1 recombinant protein  >1 publications with TLR9 and Eea1
 Cnpy3 recombinant protein  >1 publications with TLR9 and Cnpy3
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 IGF1R Signaling Cascade Pathway antibodies  IGF1R Signaling Cascade Pathway Diagram
 IRS-mediated Signalling Pathway antibodies  IRS-mediated Signalling Pathway Diagram
 IRS-related Events Triggered By IGF1R Pathway antibodies  IRS-related Events Triggered By IGF1R Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
Diseases associated with TLR9 recombinant proteinOrgans/Tissues associated with TLR9 recombinant protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >703 publications with TLR9 and Inflammation
 Necrosis Antibodies  >461 publications with TLR9 and Necrosis
 Disease Models, Animal Antibodies  >274 publications with TLR9 and Disease Models, Animal
 Nervous System Diseases Antibodies  >138 publications with TLR9 and Nervous System Diseases
 Hepatitis Antibodies  >103 publications with TLR9 and Hepatitis
 Neoplasms, Experimental Antibodies  >84 publications with TLR9 and Neoplasms, Experimental
 Kidney Diseases Antibodies  >78 publications with TLR9 and Kidney Diseases
 Brain Diseases Antibodies  >76 publications with TLR9 and Brain Diseases
 Fibrosis Antibodies  >47 publications with TLR9 and Fibrosis
 Lung Neoplasms Antibodies  >45 publications with TLR9 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >253 publications with TLR9 and Spleen
 Liver Antibodies  >167 publications with TLR9 and Liver
 Lymph Node Antibodies  >125 publications with TLR9 and Lymph Node
 Skin Antibodies  >106 publications with TLR9 and Skin
 Thymus Antibodies  >20 publications with TLR9 and Thymus
 Testis Antibodies  >9 publications with TLR9 and Testis
 Mammary Gland Antibodies  >2 publications with TLR9 and Mammary Gland
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions