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TGFB3 recombinant protein :: Transforming growth factor beta-3 Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1265100
SDS-PAGE
Unit / Price
0.01 mg  /  $150 +1 FREE 8GB USB
0.05 mg  /  $190 +1 FREE 8GB USB
0.1 mg  /  $285 +1 FREE 8GB USB
0.2 mg  /  $460 +1 FREE 8GB USB
0.5 mg  /  $750 +1 FREE 8GB USB
1 mg  /  $1,180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Transforming growth factor beta-3 (TGFB3), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Human Transforming growth factor beta-3 protein

 Product Gene Name   

TGFB3 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    301-412. Partial, provide the Transforming growth factor beta-3 Chain
 Sequence    ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS
 OMIM    107970
 3D Structure    ModBase 3D Structure for P10600
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 Host    E Coli
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TGFB3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for TGFB3 recombinant protein

   Involved in embryogenesis and cell differentiation.
 Product Categories/Family for TGFB3 recombinant protein    Cancer
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 SDS-PAGE of TGFB3 recombinant protein    TGFB3 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for TGFB3. It may not necessarily be applicable to this product.
 NCBI GI #    4507465
 NCBI GeneID    7043
 NCBI Accession #    NP_003230.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003239.3 [Other Products]
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 UniProt Primary Accession #    P10600 [Other Products]
 UniProt Secondary Accession #    Q8WV88 [Other Products]
 UniProt Related Accession #    P10600 [Other Products]
 Molecular Weight    16.8kD
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 NCBI Official Full Name    transforming growth factor beta-3 preproprotein
 NCBI Official Synonym Full Names    transforming growth factor beta 3
 NCBI Official Symbol    TGFB3 [Similar Products]
 NCBI Official Synonym Symbols   
ARVD; RNHF; ARVD1; TGF-beta3
[Similar Products]
 NCBI Protein Information    transforming growth factor beta-3
 UniProt Protein Name    Transforming growth factor beta-3
 Protein Family    Transforming growth factor
 UniProt Gene Name    TGFB3 [Similar Products]
 UniProt Synonym Gene Names    TGF-beta-3; LAP [Similar Products]
 UniProt Entry Name    TGFB3_HUMAN
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 NCBI Summary for TGFB3    This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and is involved in embryogenesis and cell differentiation. Defects in this gene are a cause of familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Mar 2009]
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 UniProt Comments for TGFB3    TGFB3: Involved in embryogenesis and cell differentiation. Homodimer; disulfide-linked. Interacts with ASPN. Belongs to the TGF-beta family.

Protein type: Secreted; Ligand, receptor tyrosine kinase; Cell development/differentiation; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 14q24

Cellular Component: cell soma; cell surface; extracellular matrix; extracellular region; extracellular space; nucleus; plasma membrane; proteinaceous extracellular matrix; T-tubule

Molecular Function: cytokine activity; growth factor activity; identical protein binding; protein binding; protein heterodimerization activity; punt binding; transforming growth factor beta binding

Biological Process: activation of MAPK activity; aging; alveolus development; blood coagulation; cell development; cell growth; embryonic neurocranium morphogenesis; extracellular matrix organization and biogenesis; female pregnancy; gut development; in utero embryonic development; inner ear development; intercellular junction assembly and maintenance; mammary gland development; negative regulation of cell proliferation; negative regulation of DNA replication; negative regulation of neuron apoptosis; negative regulation of transforming growth factor beta receptor signaling pathway; odontogenesis; palate development; platelet activation; platelet degranulation; positive regulation of apoptosis; positive regulation of bone mineralization; positive regulation of cell division; positive regulation of collagen biosynthetic process; positive regulation of DNA replication; positive regulation of filopodium formation; positive regulation of protein secretion; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of apoptosis; regulation of cell proliferation; regulation of MAPKKK cascade; response to estrogen stimulus; response to hypoxia; response to progesterone stimulus; salivary gland morphogenesis; SMAD protein nuclear translocation; transforming growth factor beta receptor signaling pathway; uterine wall breakdown

Disease: Arrhythmogenic Right Ventricular Dysplasia, Familial, 1; Rienhoff Syndrome
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Product References and Citations for TGFB3 recombinant protein

   Identification of another member of the transforming growth factor type beta gene family.ten Dijke P., Hansen P., Iwata K., Pieler C., Foulkes J.G.Proc. Natl. Acad. Sci. U.S.A. 85:4715-4719(1988)
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 Research Articles on TGFB3    1. TGF-beta3 mediates the attenuating effect of MSCs on both the proliferation and extracellular matrix production of human keloid fibroblasts and decreases skin fibrosis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TGFB3 recombinant proteinPathways associated with TGFB3 recombinant protein
 Reference Product  PubMed Publications
 TGFB2 recombinant protein  >607 publications with TGFB3 and TGFB2
 SMAD2 recombinant protein  >93 publications with TGFB3 and SMAD2
 SMAD3 recombinant protein  >67 publications with TGFB3 and SMAD3
 SMAD4 recombinant protein  >41 publications with TGFB3 and SMAD4
 TGFBR3 recombinant protein  >29 publications with TGFB3 and TGFBR3
 TGFBR1 recombinant protein  >15 publications with TGFB3 and TGFBR1
 TGFBR2 recombinant protein  >15 publications with TGFB3 and TGFBR2
 SMAD6 recombinant protein  >7 publications with TGFB3 and SMAD6
 FMOD recombinant protein  >2 publications with TGFB3 and FMOD
 ACVRL1 recombinant protein  >1 publications with TGFB3 and ACVRL1
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 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
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 Chronic Myeloid Leukemia Pathway antibodies  Chronic Myeloid Leukemia Pathway Diagram
Diseases associated with TGFB3 recombinant proteinOrgans/Tissues associated with TGFB3 recombinant protein
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >208 publications with TGFB3 and Fibrosis
 Disease Models, Animal Antibodies  >122 publications with TGFB3 and Disease Models, Animal
 Cleft Palate Antibodies  >114 publications with TGFB3 and Cleft Palate
 Cardiovascular Diseases Antibodies  >97 publications with TGFB3 and Cardiovascular Diseases
 Inflammation Antibodies  >89 publications with TGFB3 and Inflammation
 Necrosis Antibodies  >71 publications with TGFB3 and Necrosis
 Heart Diseases Antibodies  >60 publications with TGFB3 and Heart Diseases
 Lung Diseases Antibodies  >43 publications with TGFB3 and Lung Diseases
 Breast Neoplasms Antibodies  >42 publications with TGFB3 and Breast Neoplasms
 Hypertrophy Antibodies  >40 publications with TGFB3 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >403 publications with TGFB3 and Bone
 Connective Tissue Antibodies  >279 publications with TGFB3 and Connective Tissue
 Embryonic Tissue Antibodies  >158 publications with TGFB3 and Embryonic Tissue
 Bone Marrow Antibodies  >145 publications with TGFB3 and Bone Marrow
 Mouth Antibodies  >131 publications with TGFB3 and Mouth
 Heart Antibodies  >86 publications with TGFB3 and Heart
 Lung Antibodies  >81 publications with TGFB3 and Lung
 Eye Antibodies  >76 publications with TGFB3 and Eye
 Brain Antibodies  >75 publications with TGFB3 and Brain
 Liver Antibodies  >57 publications with TGFB3 and Liver
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