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TAGLN2 recombinant protein :: Transgelin-2 (TAGLN2) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS951864 TAGLN2 recombinant protein
Unit / Price
0.5 mg (E-Coli)  /  $945 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $945 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,170 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,170 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,410 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,410 +1 FREE 8GB USB
1 mg (Yeast)  /  $1,875 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,875 +2 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Transgelin-2 (TAGLN2), Recombinant Protein

 Also Known As   

Recombinant Human Transgelin-2 (TAGLN2)

 Product Synonym Names    Transgelin-2; SM22-alpha homolog
 Product Gene Name   

TAGLN2 recombinant protein

[Similar Products]
 Product Synonym Gene Name    TAGLN2; KIAA0120; CDABP0035 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    2-199
 OMIM    604634
 3D Structure    ModBase 3D Structure for P37802
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Homo sapiens (Human)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TAGLN2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for TAGLN2. It may not necessarily be applicable to this product.
 NCBI GI #    469608407
 NCBI GeneID    8407
 NCBI Accession #    NP_001264152.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001277223.1 [Other Products]
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 UniProt Primary Accession #    P37802 [Other Products]
 UniProt Secondary Accession #    Q5JRQ6; Q5JRQ7; Q6FGI1; Q9BUH5; Q9H4P0; E9KL39 [Other Products]
 UniProt Related Accession #    P37802 [Other Products]
 Molecular Weight    24,454 Da
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 NCBI Official Full Name    transgelin-2 isoform b
 NCBI Official Synonym Full Names    transgelin 2
 NCBI Official Symbol    TAGLN2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    transgelin-2; SM22-alpha homolog; epididymis tissue protein Li 7e
 UniProt Protein Name    Transgelin-2
 UniProt Synonym Protein Names   
Epididymis tissue protein Li 7e; SM22-alpha homolog
 Protein Family    Transgelin
 UniProt Gene Name    TAGLN2 [Similar Products]
 UniProt Synonym Gene Names    KIAA0120 [Similar Products]
 UniProt Entry Name    TAGL2_HUMAN
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 NCBI Summary for TAGLN2    The protein encoded by this gene is similar to the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The specific function of this protein has not yet been determined, although it is thought to be a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]
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 UniProt Comments for TAGLN2    TAGLN2: a cytoskeletal protein of the calponin family. One of the earliest markers of differentiated smooth muscle. Expressed in the smooth, cardiac, and skeletal muscle cells during early embryogenesis. Becomes restricted to vascular and visceral smooth muscle cells in late fetal development and adulthood. Its expression is abolished by activated Ras. Ras-dependent and Ras-independent mechanisms can cause the down-regulation of transgelin in breast and colon cancer cells lines and tumor samples.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1q21-q25

Cellular Component: vesicle

Molecular Function: actin filament binding; protein binding

Biological Process: epithelial cell differentiation
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 Research Articles on TAGLN2    1. PTTG1 and TAGLN2 are highly expressed in human pancreatic cancer, and the positive expression of PTTG1 is associated with the gender of cancer patients, suggesting that it may represent a potential therapeutic target for the treatment of pancreatic cancer
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TAGLN2 recombinant proteinDiseases associated with TAGLN2 recombinant protein
 Reference Product  PubMed Publications
 ANXA2 recombinant protein  >1 publications with TAGLN2 and ANXA2
 ACTB recombinant protein  >1 publications with TAGLN2 and ACTB
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with TAGLN2 and Nervous System Diseases
 Neoplasm Metastasis Antibodies  >4 publications with TAGLN2 and Neoplasm Metastasis
 Liver Diseases Antibodies  >3 publications with TAGLN2 and Liver Diseases
 Liver Neoplasms Antibodies  >3 publications with TAGLN2 and Liver Neoplasms
 Neural Tube Defects Antibodies  >3 publications with TAGLN2 and Neural Tube Defects
 Fibrosis Antibodies  >2 publications with TAGLN2 and Fibrosis
 Brain Diseases Antibodies  >2 publications with TAGLN2 and Brain Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with TAGLN2 and Carcinoma, Hepatocellular
 Hepatitis Antibodies  >1 publications with TAGLN2 and Hepatitis
 Hyperplasia Antibodies  >1 publications with TAGLN2 and Hyperplasia
Organs/Tissues associated with TAGLN2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >16 publications with TAGLN2 and Muscle
 Lung Antibodies  >3 publications with TAGLN2 and Lung
 Ovary Antibodies  >2 publications with TAGLN2 and Ovary
 Lymph Antibodies  >2 publications with TAGLN2 and Lymph
 Uterus Antibodies  >2 publications with TAGLN2 and Uterus
 Lymph Node Antibodies  >2 publications with TAGLN2 and Lymph Node
 Liver Antibodies  >2 publications with TAGLN2 and Liver
 Bone Antibodies  >1 publications with TAGLN2 and Bone
 Kidney Antibodies  >1 publications with TAGLN2 and Kidney
 Blood Antibodies  >1 publications with TAGLN2 and Blood
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