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Trpv1 recombinant protein :: Transient receptor potential cation channel subfamily V member 1 (Trpv1) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1078212 Trpv1 recombinant protein
Unit / Price
0.05 mg (Baculovirus)  /  $1,680 +2 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,835 +2 FREE 8GB USB
0.5 mg (Yeast)  /  $1,980 +2 FREE 8GB USB
0.1 mg (Baculovirus)  /  $2,090 +2 FREE 8GB USB
1 mg (E-Coli)  /  $2,230 +2 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $2,335 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,610 +3 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,890 +3 FREE 8GB USB
0.5 mg (Baculovirus)  /  $3,310 +4 FREE 8GB USB
1 mg (Baculovirus)  /  $4,130 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Transient receptor potential cation channel subfamily V member 1 (Trpv1), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Rat Transient receptor potential cation channel subfamily V member 1 (Trpv1) , partial

 Product Gene Name   

Trpv1 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-432. Provide the complete cytoplasmic domain at the N-terminal.
 Sequence    MEQRASLDSE ESESPPQENS CLDPPDRDPN CKPPPVKPHI FTTRSRTRLF GKGDSEEASP LDCPYEEGGL ASCPIITVSS VLTIQRPGDG PASVRPSSQD SVSAGEKPPR LYDRRSIFDA VAQSNCQELE SLLPFLQRSK KRLTDSEFKD PETGKTCLLK AMLNLHNGQN DTIALLLDVA RKTDSLKQFV NASYTDSYYK GQTALHIAIE RRNMTLVTLL VENGADVQAA ANGDFFKKTK GRPGFYFGEL PLSLAACTNQ LAIVKFLLQN SWQPADISAR DSVGNTVLHA LVEVADNTVD NTKFVTSMYN EILILGAKLH PTLKLEEITN RKGLTPLALA ASSGKIGVLA YILQREIHEP ECRHLSRKFT EWAYGPVHSS LYDLSCIDTC EKNSVLEVIA YSSSETPNRH DMLLVEPLNR LLQDKWDRFV KR
 3D Structure    ModBase 3D Structure for O35433
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rattus norvegicus (Rat)
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Trpv1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Trpv1. It may not necessarily be applicable to this product.
 NCBI GI #    14010883
 NCBI GeneID    83810
 NCBI Accession #    NP_114188.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_031982.1 [Other Products]
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 UniProt Primary Accession #    O35433 [Other Products]
 UniProt Secondary Accession #    Q920B3; Q920B4; Q9JLM0; Q9JM56; Q9JM57 [Other Products]
 UniProt Related Accession #    O35433 [Other Products]
 Molecular Weight    54,420 Da
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 NCBI Official Full Name    transient receptor potential cation channel subfamily V member 1
 NCBI Official Synonym Full Names    transient receptor potential cation channel, subfamily V, member 1
 NCBI Official Symbol    Trpv1 [Similar Products]
 NCBI Official Synonym Symbols   
Vr1; Vr1l1; VR.5'sv; TRPV1_SON
[Similar Products]
 NCBI Protein Information    transient receptor potential cation channel subfamily V member 1
 UniProt Protein Name    Transient receptor potential cation channel subfamily V member 1
 UniProt Synonym Protein Names   
Capsaicin receptor; Osm-9-like TRP channel 1; OTRPC1; Vanilloid receptor 1; Vanilloid receptor type 1-like
 Protein Family    Transient receptor potential cation channel subfamily
 UniProt Gene Name    Trpv1 [Similar Products]
 UniProt Synonym Gene Names    Vr1; Vr1l; TrpV1; OTRPC1 [Similar Products]
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 NCBI Summary for Trpv1    ion channel that demonstrates heat-evoked membrane currents [RGD, Feb 2006]
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 UniProt Comments for Trpv1    Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca2+-dependent outward rectification, followed by a long-lasting refractory state. Mild extracellular acidic pH (6.5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions (pH <6) directly activate the channel. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis.
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 Research Articles on Trpv1    1. results suggest that noradrenaline directly acts on dorsal root ganglion neurons to inhibit the activity of TRPV1 depending on the activation of alpha2-adrenoceptors followed by the inhibition of the adenylate cyclase/cAMP/protein kinase A pathway
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Trpv1 recombinant proteinDiseases associated with Trpv1 recombinant protein
 Products by Pathway  Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Disease Name  Pubmed Publications
 Pain Antibodies  >1308 publications with Trpv1 and Pain
 Nervous System Diseases Antibodies  >879 publications with Trpv1 and Nervous System Diseases
 Inflammation Antibodies  >625 publications with Trpv1 and Inflammation
 Hyperalgesia Antibodies  >448 publications with Trpv1 and Hyperalgesia
 Drug Toxicity Antibodies  >127 publications with Trpv1 and Drug Toxicity
 Neoplasms Antibodies  >89 publications with Trpv1 and Neoplasms
 Necrosis Antibodies  >72 publications with Trpv1 and Necrosis
 Hypertension Antibodies  >67 publications with Trpv1 and Hypertension
 Urinary Bladder Diseases Antibodies  >57 publications with Trpv1 and Urinary Bladder Diseases
 Lung Diseases Antibodies  >56 publications with Trpv1 and Lung Diseases
Organs/Tissues associated with Trpv1 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >880 publications with Trpv1 and Nerve
 Dorsal Root Ganglion Antibodies  >577 publications with Trpv1 and Dorsal Root Ganglion
 Kidney Antibodies  >116 publications with Trpv1 and Kidney
 Prostate Antibodies  >19 publications with Trpv1 and Prostate
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