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TSNAX recombinant protein :: Translin-Associated Factor X Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS145528 TSNAX recombinant protein
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.02 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $3,515 +4 FREE 8GB USB
 
 Product Name   

Translin-Associated Factor X (TSNAX), Recombinant Protein

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 Also Known As   

Recombinant Human Translin-Associated Factor X

 Product Synonym Names    TSNAX Human; Translin-Associated Factor X Human Recombinant; TRAX; Translin-associated protein X; Translin-associated factor X
 Product Gene Name   

TSNAX recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    MGSSHHH HHH SSGLVPRGSH MGSMSN KEGS GGFRKRKHDN FPHNQRREGK DVNSSSPVML AFKSFQQELD ARHDKYERLV KLSRDITVES KRTIFLLHRI TSAPDMEDIL TESEIKLDGV RQKIFQVAQE LSGEDMHQFH RAITTGLQEY VEAVSFQHFI KTRSLISMDE INKQLIFTTE DNGKENKTPS SDAQDKQFGT WRLRVTPVDY LLGVADLTGE LMRMCINSVG NGDIDTPFEV SQFLRQVYDG FSFIGNTGPY EVSKKLYTLK QSLAKVENAC YALKVRGSEI PKHMLADVFS VKTEMIDQEE GIS
 OMIM    602964
 3D Structure    ModBase 3D Structure for Q99598
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 Host    E Coli
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 Purity/Purification    Greater than 90.0% as determined by SDS-PAGE.
 Form/Format    TSNAX protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.2M NaCl, 50% glycerol and 1mM DTT.
Sterile Filtered clear solution.
 Concentration    0.25mg/ml (lot specific)
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 Preparation and Storage    Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 Degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
 Other Notes    Small volumes of TSNAX recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for TSNAX recombinant protein

   Description: TSNAX Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 313 amino acids (1-290 a.a.) and having a molecular mass of 35kDa.TSNAX is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: TSNAX is a member of translin family. TSNAX particularly interacts with translin, a DNA-binding protein that binds consensus sequences at breakpoint junctions of chromosomal translocations. TSNAX works in combination with TSN as an endonuclease involves in the activation of the RNA-induced silencing complex (RISC). TSNAX has bipartite nuclear targeting sequences that afford nuclear transport for translin, which lacks any nuclear targeting motifs.
 Product Categories/Family for TSNAX recombinant protein    RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins
NCBI/Uniprot data below describe general gene information for TSNAX. It may not necessarily be applicable to this product.
 NCBI GI #    5174731
 NCBI GeneID    7257
 NCBI Accession #    NP_005990.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005999.2 [Other Products]
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 UniProt Primary Accession #    Q99598 [Other Products]
 UniProt Secondary Accession #    B1APC6 [Other Products]
 UniProt Related Accession #    Q99598 [Other Products]
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 NCBI Official Full Name    translin-associated protein X
 NCBI Official Synonym Full Names    translin-associated factor X
 NCBI Official Symbol    TSNAX [Similar Products]
 NCBI Official Synonym Symbols   
TRAX
[Similar Products]
 NCBI Protein Information    translin-associated protein X; translin-like protein
 UniProt Protein Name    Translin-associated protein X
 UniProt Synonym Protein Names   
Translin-associated factor X
 Protein Family    Translin-associated protein
 UniProt Gene Name    TSNAX [Similar Products]
 UniProt Synonym Gene Names    TRAX [Similar Products]
 UniProt Entry Name    TSNAX_HUMAN
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 NCBI Summary for TSNAX    This gene encodes a protein which specifically interacts with translin, a DNA-binding protein that binds consensus sequences at breakpoint junctions of chromosomal translocations. The encoded protein contains bipartite nuclear targeting sequences that may provide nuclear transport for translin, which lacks any nuclear targeting motifs. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TSNAX    TSNAX: Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis. Belongs to the translin family.

Protein type: Nuclear receptor co-regulator; DNA-binding

Chromosomal Location of Human Ortholog: 1q42.1

Cellular Component: Golgi apparatus; perinuclear region of cytoplasm; cytoplasm; cytosol; nucleus

Molecular Function: endoribonuclease activity; DNA binding; sequence-specific DNA binding; metal ion binding; single-stranded DNA binding; protein transporter activity

Biological Process: protein transport; multicellular organismal development; gene expression; spermatogenesis; cell differentiation
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 Research Articles on TSNAX    1. High chimeric TSNAX-DISC1 resulting from intergenic splicing is associated with endometrial carcinoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TSNAX recombinant proteinPathways associated with TSNAX recombinant protein
 Reference Product  PubMed Publications
 TSN recombinant protein  >26 publications with TSNAX and TSN
 GOLGA3 recombinant protein  >2 publications with TSNAX and GOLGA3
 EIF2C2 recombinant protein  >1 publications with TSNAX and EIF2C2
 AKAP9 recombinant protein  >1 publications with TSNAX and AKAP9
 SUN1 recombinant protein  >1 publications with TSNAX and SUN1
 TSNAXIP1 recombinant protein  >1 publications with TSNAX and TSNAXIP1
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Regulatory RNA Pathways antibodies  Regulatory RNA Pathways Diagram
 Small Interfering RNA (siRNA) Biogenesis Pathway antibodies  Small Interfering RNA (siRNA) Biogenesis Pathway Diagram
Diseases associated with TSNAX recombinant proteinOrgans/Tissues associated with TSNAX recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with TSNAX and Nervous System Diseases
 Learning Disorders Antibodies  >2 publications with TSNAX and Learning Disorders
 Atrophy Antibodies  >1 publications with TSNAX and Atrophy
 Brain Diseases Antibodies  >1 publications with TSNAX and Brain Diseases
 Abnormalities, Multiple Antibodies  >1 publications with TSNAX and Abnormalities, Multiple
 Neoplasms, Experimental Antibodies  >1 publications with TSNAX and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >19 publications with TSNAX and Nerve
 Brain Antibodies  >19 publications with TSNAX and Brain
 Testis Antibodies  >10 publications with TSNAX and Testis
 Kidney Antibodies  >3 publications with TSNAX and Kidney
 Embryonic Tissue Antibodies  >2 publications with TSNAX and Embryonic Tissue
 Liver Antibodies  >2 publications with TSNAX and Liver
 Blood Antibodies  >2 publications with TSNAX and Blood
 Stomach Antibodies  >1 publications with TSNAX and Stomach
 Uterus Antibodies  >1 publications with TSNAX and Uterus
 Eye Antibodies  >1 publications with TSNAX and Eye
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