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HADHB recombinant protein :: Trifunctional enzyme subunit beta, mitochondrial (HADHB) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1154225 HADHB recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $860 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,080 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,150 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,265 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,280 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,330 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,370 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,450 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,800 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,970 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,010 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,205 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,590 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Trifunctional enzyme subunit beta, mitochondrial (HADHB), Recombinant Protein

 Also Known As   

Recombinant Human Trifunctional enzyme subunit beta, mitochondrial (HADHB)

 Product Gene Name   

HADHB recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    34-474aa, Full Length of Mature Protein
 Sequence    AAPAVQTKTK KTLAKPNIRN VVVVDGVRTP FLLSGTSYKD LMPHDLARAA LTGLLHRTSV PKEVVDYIIF GTVIQEVKTS NVAREAALGA GFSDKTPAHT VTMACISANQ AMTTGVGLIA SGQCDVIVAG GVELMSDVPI RHSRKMRKLM LDLNKAKSMG QRLSLISKFR FNFLAPELPA VSEFSTSETM GHSADRLAAA FAVSRLEQDE YALRSHSLAK KAQDEGLLSD VVPFKVPGKD TVTKDNGIRP SSLEQMAKLK PAFIKPYGTV TAANSSFLTD GASAMLIMAE EKALAMGYKP KAYLRDFMYV SQDPKDQLLL GPTYATPKVL EKAGLTMNDI DAFEFHEAFS GQILANFKAM DSDWFAENYM GRKTKVGLPP LEKFNNWGGS LSLGHPFGAT GCRLVMAAAN RLRKEGGQYG LVAACAAGGQ GHAMIVEAYP K
 OMIM    143450
 3D Structure    ModBase 3D Structure for P55084
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of HADHB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for HADHB recombinant protein

   This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found; however, their full-length nature is not known.
NCBI/Uniprot data below describe general gene information for HADHB. It may not necessarily be applicable to this product.
 NCBI GI #    4504327
 NCBI GeneID    3032
 NCBI Accession #    NP_000174.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000183.2 [Other Products]
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 UniProt Primary Accession #    P55084 [Other Products]
 UniProt Secondary Accession #    O14969; Q53TA6; Q96C77; Q9H3F5; Q9T2V8; B2RB16; B4E2W0 [Other Products]
 UniProt Related Accession #    P55084 [Other Products]
 Molecular Weight    48,880 Da
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 NCBI Official Full Name    trifunctional enzyme subunit beta, mitochondrial isoform 1
 NCBI Official Synonym Full Names    hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
 NCBI Official Symbol    HADHB [Similar Products]
 NCBI Official Synonym Symbols   
ECHB; MTPB; MSTP029; TP-BETA
[Similar Products]
 NCBI Protein Information    trifunctional enzyme subunit beta, mitochondrial
 UniProt Protein Name    Trifunctional enzyme subunit beta, mitochondrial
 UniProt Synonym Protein Names   
TP-betaIncluding the following 1 domains:3-ketoacyl-CoA thiolase (EC:2.3.1.16)Alternative name(s):Acetyl-CoA acyltransferase; Beta-ketothiolase
 Protein Family    Trifunctional enzyme
 UniProt Gene Name    HADHB [Similar Products]
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 NCBI Summary for HADHB    This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
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 Research Articles on HADHB    1. Exposure to bezafibrate (400 muM for 48 h) increased the abundance of HADHA and HADHB mRNAs.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HADHB recombinant proteinPathways associated with HADHB recombinant protein
 Reference Product  PubMed Publications
 HADHA recombinant protein  >13 publications with HADHB and HADHA
 EHHADH recombinant protein  >2 publications with HADHB and EHHADH
 ACADL recombinant protein  >1 publications with HADHB and ACADL
 Products by Pathway  Pathway Diagram
 Acyl Chain Remodeling Of CL Pathway antibodies  Acyl Chain Remodeling Of CL Pathway Diagram
 Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway antibodies  Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway Diagram
 Beta Oxidation Of Hexanoyl-CoA To Butanoyl-CoA Pathway antibodies  Beta Oxidation Of Hexanoyl-CoA To Butanoyl-CoA Pathway Diagram
 Beta Oxidation Of Lauroyl-CoA To Decanoyl-CoA-CoA Pathway antibodies  Beta Oxidation Of Lauroyl-CoA To Decanoyl-CoA-CoA Pathway Diagram
 Beta Oxidation Of Myristoyl-CoA To Lauroyl-CoA Pathway antibodies  Beta Oxidation Of Myristoyl-CoA To Lauroyl-CoA Pathway Diagram
 Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway antibodies  Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway Diagram
 Beta Oxidation Of Palmitoyl-CoA To Myristoyl-CoA Pathway antibodies  Beta Oxidation Of Palmitoyl-CoA To Myristoyl-CoA Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway Diagram
Diseases associated with HADHB recombinant proteinOrgans/Tissues associated with HADHB recombinant protein
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >11 publications with HADHB and Fatty Liver
 Liver Diseases Antibodies  >6 publications with HADHB and Liver Diseases
 Lipid Metabolism Disorders Antibodies  >6 publications with HADHB and Lipid Metabolism Disorders
 Inflammation Antibodies  >3 publications with HADHB and Inflammation
 Cardiovascular Diseases Antibodies  >3 publications with HADHB and Cardiovascular Diseases
 Insulin Resistance Antibodies  >3 publications with HADHB and Insulin Resistance
 Weight Gain Antibodies  >3 publications with HADHB and Weight Gain
 Liver Failure, Acute Antibodies  >3 publications with HADHB and Liver Failure, Acute
 Fibrosis Antibodies  >2 publications with HADHB and Fibrosis
 Necrosis Antibodies  >2 publications with HADHB and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >15 publications with HADHB and Liver
 Muscle Antibodies  >7 publications with HADHB and Muscle
 Heart Antibodies  >7 publications with HADHB and Heart
 Blood Antibodies  >6 publications with HADHB and Blood
 Adipose Tissue Antibodies  >4 publications with HADHB and Adipose Tissue
 Connective Tissue Antibodies  >3 publications with HADHB and Connective Tissue
 Skin Antibodies  >2 publications with HADHB and Skin
 Lung Antibodies  >2 publications with HADHB and Lung
 Kidney Antibodies  >2 publications with HADHB and Kidney
 Nerve Antibodies  >2 publications with HADHB and Nerve
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