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TPBG recombinant protein :: Trophoblast glycoprotein (TPBG) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS1445556 TPBG recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $730 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $855 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $985 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $990 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,080 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,150 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,235 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,255 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,300 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,530 +1 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,805 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,875 +2 FREE 8GB USB
1 mg (Yeast)  /  $1,975 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,405 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Trophoblast glycoprotein (TPBG), Recombinant Protein

 Also Known As   

Recombinant Human Trophoblast glycoprotein (TPBG), partial

 Product Gene Name   

TPBG recombinant protein

[Similar Products]
 Product Synonym Gene Name    TPBG [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    32-355. Partial, provide the complete extracellular domain.
 Sequence    SSPTSSASSF SSSAPFLASA VSAQPPLPDQ CPALCECSEA ARTVKCVNRN LTEVPTDLPA YVRNLFLTGN QLAVLPAGAF ARRPPLAELA ALNLSGSRLD EVRAGAFEHL PSLRQLDLSH NPLADLSPFA FSGSNASVSA PSPLVELILN HIVPPEDERQ NRSFEGMVVA ALLAGRALQG LRRLELASNH FLYLPRDVLA QLPSLRHLDL SNNSLVSLTY VSFRNLTHLE SLHLEDNALK VLHNGTLAEL QGLPHIRVFL DNNPWVCDCH MADMVTWLKE TEVVQGKDRL TCAYPEKMRN RVLLELNSAD LDCDPILPPS LQTS
 OMIM    190920
 3D Structure    ModBase 3D Structure for Q13641
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Human
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of TPBG recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for TPBG recombinant protein

   This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5 UTR results in multiple transcript variants that encode the same protein.
NCBI/Uniprot data below describe general gene information for TPBG. It may not necessarily be applicable to this product.
 NCBI GI #    262205665
 NCBI GeneID    7162
 NCBI Accession #    NP_001159864.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001166392.1 [Other Products]
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 UniProt Primary Accession #    Q13641 [Other Products]
 UniProt Secondary Accession #    A8K555 [Other Products]
 UniProt Related Accession #    Q13641 [Other Products]
 Molecular Weight    46,032 Da
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 NCBI Official Full Name    trophoblast glycoprotein
 NCBI Official Synonym Full Names    trophoblast glycoprotein
 NCBI Official Symbol    TPBG [Similar Products]
 NCBI Official Synonym Symbols   
5T4; M6P1; 5T4AG; WAIF1
[Similar Products]
 NCBI Protein Information    trophoblast glycoprotein
 UniProt Protein Name    Trophoblast glycoprotein
 UniProt Synonym Protein Names   
5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; M6P1; Wnt-activated inhibitory factor 1; WAIF1
 Protein Family    Trophoblast glycoprotein
 UniProt Gene Name    TPBG [Similar Products]
 UniProt Synonym Gene Names    5T4; 5T4 oncotrophoblast glycoprotein; WAIF1 [Similar Products]
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 NCBI Summary for TPBG    This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]
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 UniProt Comments for TPBG    May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
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 Research Articles on TPBG    1. Collectively, these findings demonstrate that an anti-5T4 antibody-drug conjugate reduces the fraction of cancer stem cells (CSC), and prevents local recurrence and suggest a novel therapeutic approach for patients with head and neck squamous cell carcinoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with TPBG recombinant proteinOrgans/Tissues associated with TPBG recombinant protein
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with TPBG and Neoplasms
 Disease Models, Animal Antibodies  >3 publications with TPBG and Disease Models, Animal
 Lung Neoplasms Antibodies  >1 publications with TPBG and Lung Neoplasms
 Kidney Diseases Antibodies  >1 publications with TPBG and Kidney Diseases
 Neoplasms, Experimental Antibodies  >1 publications with TPBG and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with TPBG and Brain
 Embryonic Tissue Antibodies  >2 publications with TPBG and Embryonic Tissue
 Kidney Antibodies  >1 publications with TPBG and Kidney
 Intestine Antibodies  >1 publications with TPBG and Intestine
 Eye Antibodies  >1 publications with TPBG and Eye
 Lung Antibodies  >1 publications with TPBG and Lung
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