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Tdo2 recombinant protein :: Tryptophan 2,3-dioxygenase Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS958462
SDS-PAGE
Unit / Price
0.01 mg (E-Coli)  /  $135 +1 FREE 8GB USB
0.05 mg (E-Coli)  /  $255 +1 FREE 8GB USB
0.1 mg (E-Coli)  /  $420 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $665 +1 FREE 8GB USB
0.05 mg (Yeast)  /  $925 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,055 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,090 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,240 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,300 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,335 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,405 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $1,920 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $1,970 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,140 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,530 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tryptophan 2,3-dioxygenase (Tdo2), Recombinant Protein

★Popular Item★
 Also Known As   

Recombinant Rat Tryptophan 2,3-dioxygenase(Tdo2)

 Product Synonym Names    Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; Tryptophan pyrrolase; Tryptophanase
 Product Gene Name   

Tdo2 recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-406aa; Full Length
 Sequence    MSGCPFSGNS VGYTLKNLSM EDNEEDGAQT GVNRASKGGL IYGDYLQLEK ILNAQELQSE IKGNKIHDEH LFIITHQAYE LWFKQILWEL DSVREIFQNG HVRDERNMLK VMTRMHRVVV IFKLLVQQFS VLETMTALDF NDFREYLSPA SGFQSLQFRL LENKIGVLQS LRVPYNRKHY RDNFEGDYNE LLLKSEQEQT LLQLVEAWLE RTPGLEPHGF NFWGKFEKNI LKGLEEEFLK IQAKKDSEEK EEQMAEFRKQ KEVLLCLFDE KRHDYLLSKG ERRLSYRALQ GALMIYFYRE EPRFQVPFQL LTSLMDIDTL MTKWRYNHVC MVHRMLGSKA GTGGSSGYYY LRSTVSDRYK VFVDLFNLSS YLVPRHWIPK MNPIIHKFLY TAEYSDSSYF SSDESD
 3D Structure    ModBase 3D Structure for P21643
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    Greater than 90% as determined by SDS-PAGE. (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rat
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 Preparation and Storage    Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Tdo2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Tdo2 recombinant protein

   Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin.
 Product Categories/Family for Tdo2 recombinant protein    Metabolism
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 SDS-PAGE of Tdo2 recombinant protein    Tdo2 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
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NCBI/Uniprot data below describe general gene information for Tdo2. It may not necessarily be applicable to this product.
 NCBI GI #    11693136
 NCBI GeneID    64206
 NCBI Accession #    NP_071798.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_022403.2 [Other Products]
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 UniProt Primary Accession #    P21643 [Other Products]
 UniProt Secondary Accession #    Q5EBC2; Q6LBW3 [Other Products]
 UniProt Related Accession #    P21643 [Other Products]
 Molecular Weight    60.66kD
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 NCBI Official Full Name    tryptophan 2,3-dioxygenase
 NCBI Official Synonym Full Names    tryptophan 2,3-dioxygenase
 NCBI Official Symbol    Tdo2 [Similar Products]
 NCBI Official Synonym Symbols   
TO; Tdo
[Similar Products]
 NCBI Protein Information    tryptophan 2,3-dioxygenase
 UniProt Protein Name    Tryptophan 2,3-dioxygenase
 UniProt Synonym Protein Names   
Tryptamin 2,3-dioxygenase
 Protein Family    Tryptophan 2,3-dioxygenase
 UniProt Gene Name    Tdo2 [Similar Products]
 UniProt Synonym Gene Names    Tdo; TDO; TO; TRPO [Similar Products]
 UniProt Entry Name    T23O_RAT
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 NCBI Summary for Tdo2    rate-limiting enzyme in the catabolism of tryptophan [RGD, Feb 2006]
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 UniProt Comments for Tdo2    TDO2: Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin. Belongs to the tryptophan 2,3-dioxygenase family.

Protein type: Amino Acid Metabolism - tryptophan; Oxidoreductase; EC 1.13.11.11

Molecular Function: amino acid binding; heme binding; metal ion binding; oxygen binding; tryptophan 2,3-dioxygenase activity

Biological Process: tryptophan catabolic process to acetyl-CoA; tryptophan catabolic process to kynurenine; tryptophan metabolic process
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Product References and Citations for Tdo2 recombinant protein

   "Nucleotide sequence of a fragment of the rat tryptophan oxygenase gene showing high affinity to glucocorticoid receptor in vitro." Merkulov V.M., Merkulova T.I. Biochim. Biophys. Acta 1132:100-102(1992)
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 Research Articles on Tdo2    1. Results show that stress-induced corticosterone and consequent activation of hepatic TDO, tryptophan metabolism and production of kynurenine provoke a depression-related behavioural phenotype
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Tdo2 recombinant proteinDiseases associated with Tdo2 recombinant protein
 Products by Pathway  Pathway Diagram
 Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway antibodies  Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Tryptophan Catabolism Pathway antibodies  Tryptophan Catabolism Pathway Diagram
 Tryptophan Metabolism Pathway antibodies  Tryptophan Metabolism Pathway Diagram
 Tryptophan Metabolism Pathway antibodies  Tryptophan Metabolism Pathway Diagram
 Tryptophan Metabolism Pathway antibodies  Tryptophan Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >9 publications with Tdo2 and Nervous System Diseases
 Learning Disorders Antibodies  >4 publications with Tdo2 and Learning Disorders
 Disease Models, Animal Antibodies  >4 publications with Tdo2 and Disease Models, Animal
 Memory Disorders Antibodies  >3 publications with Tdo2 and Memory Disorders
 Inflammation Antibodies  >3 publications with Tdo2 and Inflammation
 Cognition Disorders Antibodies  >2 publications with Tdo2 and Cognition Disorders
 Liver Diseases Antibodies  >2 publications with Tdo2 and Liver Diseases
 Weight Loss Antibodies  >1 publications with Tdo2 and Weight Loss
 Kidney Diseases Antibodies  >1 publications with Tdo2 and Kidney Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with Tdo2 and Carcinoma, Hepatocellular
Organs/Tissues associated with Tdo2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >8 publications with Tdo2 and Liver
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