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Wars recombinant protein :: Tryptophan--tRNA ligase, cytoplasmic (Wars) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS955209 Wars recombinant protein
Unit / Price
0.05 mg (E-Coli)  /  $900 +1 FREE 8GB USB
0.05 mg (Baculovirus)  /  $1,115 +1 FREE 8GB USB
0.2 mg (E-Coli)  /  $1,205 +1 FREE 8GB USB
0.2 mg (Yeast)  /  $1,330 +1 FREE 8GB USB
0.5 mg (E-Coli)  /  $1,330 +1 FREE 8GB USB
0.05 mg (Mammalian-Cell)  /  $1,360 +1 FREE 8GB USB
0.1 mg (Baculovirus)  /  $1,410 +1 FREE 8GB USB
0.5 mg (Yeast)  /  $1,505 +1 FREE 8GB USB
1 mg (E-Coli)  /  $1,890 +2 FREE 8GB USB
0.5 mg (Baculovirus)  /  $2,025 +2 FREE 8GB USB
0.1 mg (Mammalian-Cell)  /  $2,055 +2 FREE 8GB USB
1 mg (Yeast)  /  $2,285 +2 FREE 8GB USB
1 mg (Baculovirus)  /  $2,660 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tryptophan--tRNA ligase, cytoplasmic (Wars), Recombinant Protein

 Also Known As   

Recombinant Mouse Tryptophan--tRNA ligase, cytoplasmic (Wars)

 Product Gene Name   

Wars recombinant protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    1-481aa, Full length protein
 Sequence    MADMPSGESC TSPLELFNSI ATQGELVRSL KAGNAPKDEI DSAVKMLLSL KMSYKAAMGE EYKAGCPPGN PTAGRNCDSD ATKASEDFVD PWTVRTSSAK GIDYDKLIVQ FGSSKIDKEL INRIERATGQ RPHRFLRRGI FFSHRDMNQI LDAYENKKPF YLYTGRGPSS EAMHLGHLVP FIFTKWLQDV FNVPLVIQMS DDEKYLWKDL TLEQAYSYTV ENAKDIIACG FDINKTFIFS DLEYMGQSPG FYRNVVKIQK HVTFNQVKGI FGFTDSDCIG KISFPAVQAA PSFSNSFPKI FRDRTDIQCL IPCAIDQDPY FRMTRDVAPR IGHPKPALLH STFFPALQGA QTKMSASDPN SSIFLTDTAK QIKSKVNKHA FSGGRDTVEE HRQFGGNCEV DVSFMYLTFF LEDDDRLEQI RKDYTSGAML TGELKKTLID VLQPLIAEHQ ARRKAVTEET VKEFMTPRQL SFHFQCFCFD T
 3D Structure    ModBase 3D Structure for P32921
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >85% (SDS-PAGE) (lot specific)
 Form/Format    Liquid containing glycerol
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Mouse
 Storage Buffer    Tris-based buffer, 50% glycerol
 Tag Information    Tag type will be determined during the manufacturing process
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Wars recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Wars recombinant protein

   Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for Wars. It may not necessarily be applicable to this product.
 NCBI GI #    256818806
 NCBI GeneID    22375
 NCBI Accession #    NP_001157786.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001164314.1 [Other Products]
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 UniProt Primary Accession #    P32921 [Other Products]
 UniProt Secondary Accession #    Q80ZY4; Q99J58; Q9DC65 [Other Products]
 UniProt Related Accession #    P32921 [Other Products]
 Molecular Weight    53,641 Da
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 NCBI Official Full Name    tryptophan--tRNA ligase, cytoplasmic isoform 2
 NCBI Official Synonym Full Names    tryptophanyl-tRNA synthetase
 NCBI Official Symbol    Wars [Similar Products]
 NCBI Official Synonym Symbols   
WRS; TrpRS
[Similar Products]
 NCBI Protein Information    tryptophan--tRNA ligase, cytoplasmic
 UniProt Protein Name    Tryptophan--tRNA ligase, cytoplasmic
 UniProt Synonym Protein Names   
Tryptophanyl-tRNA synthetase; TrpRS
 Protein Family    Tryptophan--tRNA ligase
 UniProt Gene Name    Wars [Similar Products]
 UniProt Synonym Gene Names    Wrs; TrpRS [Similar Products]
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 UniProt Comments for Wars    T1-TrpRS has aminoacylation activity while T2-TrpRS lacks it. T1-TrpRS and T2-TrpRS possess angiostatic activity. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression ().
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 Research Articles on Wars    1. TrpRS plays a role in protecting against neurodegeneration is suggested, providing an insight into the pathogenesis and a possible treatment of neurodegenerative diseases.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Wars recombinant proteinDiseases associated with Wars recombinant protein
 Products by Pathway  Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Cytosolic TRNA Aminoacylation Pathway antibodies  Cytosolic TRNA Aminoacylation Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Tryptophan Metabolism Pathway antibodies  Tryptophan Metabolism Pathway Diagram
 TRNA Aminoacylation Pathway antibodies  TRNA Aminoacylation Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2758 publications with Wars and Nervous System Diseases
 Neoplasms Antibodies  >2136 publications with Wars and Neoplasms
 Cardiovascular Diseases Antibodies  >1072 publications with Wars and Cardiovascular Diseases
 Brain Diseases Antibodies  >1048 publications with Wars and Brain Diseases
 Skin Diseases Antibodies  >756 publications with Wars and Skin Diseases
 Vascular Diseases Antibodies  >749 publications with Wars and Vascular Diseases
 Pain Antibodies  >706 publications with Wars and Pain
 Fever Antibodies  >579 publications with Wars and Fever
 Heart Diseases Antibodies  >484 publications with Wars and Heart Diseases
 Hemorrhage Antibodies  >417 publications with Wars and Hemorrhage
Organs/Tissues associated with Wars recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2167 publications with Wars and Blood
 Brain Antibodies  >1313 publications with Wars and Brain
 Bone Antibodies  >1034 publications with Wars and Bone
 Skin Antibodies  >820 publications with Wars and Skin
 Heart Antibodies  >709 publications with Wars and Heart
 Lung Antibodies  >687 publications with Wars and Lung
 Eye Antibodies  >591 publications with Wars and Eye
 Muscle Antibodies  >352 publications with Wars and Muscle
 Liver Antibodies  >343 publications with Wars and Liver
 Kidney Antibodies  >264 publications with Wars and Kidney
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