NP_848027.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
59,086 Da
NCBI Official Full Name
tubulin-specific chaperone E
NCBI Official Synonym Full Names
tubulin-specific chaperone E
NCBI Official Synonym Symbols
pmn; 2610206D02Rik; C530005D02Rik [Similar Products]
NCBI Protein Information
tubulin-specific chaperone E
UniProt Protein Name
Tubulin-specific chaperone E
UniProt Synonym Protein Names
Tubulin-folding cofactor E
NCBI Summary for Tbce
This gene encodes a tubulin binding cofactor that participates in microtubule dynamics. A mouse model of progressive motor neuropathy (pmn) was discovered to harbor a single amino acid deletion in this gene. Mice that are homozygous for pmn allele exhibit progressive atrophy and premature death due to respiratory failure. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]
UniProt Comments for Tbce
Tubulin-folding protein; involved in the second step of the tubulin folding pathway and in the regulation of tubulin heterodimer dissociation (PubMed:12389029, PubMed:17184771). Required for correct organization of microtubule cytoskeleton and mitotic splindle, and maintenance of the neuronal microtubule network ().
Research Articles on Tbce
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Products associated with Tbce recombinant protein
Pathways associated with Tbce recombinant protein
Diseases associated with Tbce recombinant protein
Organs/Tissues associated with Tbce recombinant protein
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