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Ngfr recombinant protein :: Tumor necrosis factor receptor superfamily member 16 (Ngfr) Recombinant Protein

Scan QR to view Datasheet Catalog #    MBS949315 Ngfr recombinant protein
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tumor necrosis factor receptor superfamily member 16 (Ngfr), Recombinant Protein

 Also Known As   

Recombinant Rat Tumor necrosis factor receptor superfamily member 16 (Ngfr)

 Product Synonym Names    Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD_antigen=; CD271
 Product Gene Name   

Ngfr recombinant protein

[Similar Products]
 Product Synonym Gene Name    Ngfr; Tnfrsf16 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence Positions    30-251
 Sequence    K ETCSTGLYTH SGECCKACNL GEGVAQPCGA NQTVCEPCLD NVTFSDVVSA TEPCKPCTEC LGLQSMSAPC VEADDAVCRC AYGYYQDEET GHCEACSVCE VGSGLVFSCQ DKQNTVCEEC PEGTYSDEAN HVDPCLPCTV CEDTERQLRE CTPWADAECE EIPGRWIPRS TPPEGSDSTA PSTQEPEVPP EQDLVPSTVA DMVTTVMGSS QPVVTRGTTD N
 3D Structure    ModBase 3D Structure for P07174
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 Host    E Coli or Yeast or Baculovirus or Mammalian Cell
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 Purity/Purification    >90%
 Form/Format    Liquid containing glycerol; lyophilization may be available upon request.
 Tag Information    This protein contains an N-terminal tag and may also contain a C-terminal Myc-tag. N-terminal host tags may vary (His, His-SUMO, His-B2M, GST). Tag types are determined by various factors including tag-protein stability and, therefore, are subject to change; please inquire for tag information. Additional charge for Tag removal. Tag removal service standardly refers to removal of N-terminal Tag. Any C-terminal Myc-tag may remain intact unless removal of the C-terminal Myc-tag is specifically requested. In most cases tags can be successfully removed. If the lab concludes the protein is no longer stable after tag removal then your protein will be supplied with the tag intact, and you will not be charged for tag removal service.
 Sterility    Sterile filter available upon request.
 Endotoxin    Low endotoxin available upon request.
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 Species    Rattus norvegicus (Rat)
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 Preparation and Storage    Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Ngfr recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Ngfr. It may not necessarily be applicable to this product.
 NCBI GI #    291490673
 NCBI GeneID    24596
 NCBI Accession #    NP_036742.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_012610.2 [Other Products]
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 UniProt Primary Accession #    P07174 [Other Products]
 UniProt Related Accession #    P07174 [Other Products]
 Molecular Weight    45,433 Da
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 NCBI Official Full Name    tumor necrosis factor receptor superfamily member 16
 NCBI Official Synonym Full Names    nerve growth factor receptor
 NCBI Official Symbol    Ngfr [Similar Products]
 NCBI Official Synonym Symbols   
p75; LNGFR; p75NTR; RNNGFRR; Tnfrsf16
[Similar Products]
 NCBI Protein Information    tumor necrosis factor receptor superfamily member 16; p75 ICD; gp80-LNGFR; NGF receptor; nerve growth factor receptor, fast; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16)
 UniProt Protein Name    Tumor necrosis factor receptor superfamily member 16
 UniProt Synonym Protein Names   
Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD_antigen: CD271
 Protein Family    Tumor necrosis factor receptor superfamily
 UniProt Gene Name    Ngfr [Similar Products]
 UniProt Synonym Gene Names    Tnfrsf16; NGF receptor [Similar Products]
 UniProt Entry Name    TNR16_RAT
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 NCBI Summary for Ngfr    receptor that can bind NGF, BDNF, NT-3, and NT-4 [RGD, Feb 2006]
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 UniProt Comments for Ngfr    Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
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 Research Articles on Ngfr    1. Exposure to Abeta increased surface expression of p75 neurotrophin receptor, and the increase was abolished in the presence of gamma-Eno peptide.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Ngfr recombinant proteinPathways associated with Ngfr recombinant protein
 Reference Product  PubMed Publications
 Rtn4r recombinant protein  >2 publications with Ngfr and Rtn4r
 Products by Pathway  Pathway Diagram
 Axonal Growth Inhibition (RHOA Activation) Pathway antibodies  Axonal Growth Inhibition (RHOA Activation) Pathway Diagram
 Axonal Growth Stimulation Pathway antibodies  Axonal Growth Stimulation Pathway Diagram
 Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies  Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
 Ceramide Signalling Pathway antibodies  Ceramide Signalling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 NADE Modulates Death Signalling Pathway antibodies  NADE Modulates Death Signalling Pathway Diagram
 NF-kB Is Activated And Signals Survival Pathway antibodies  NF-kB Is Activated And Signals Survival Pathway Diagram
 NFG And ProNGF Binds To P75NTR Pathway antibodies  NFG And ProNGF Binds To P75NTR Pathway Diagram
 NRAGE Signals Death Through JNK Pathway antibodies  NRAGE Signals Death Through JNK Pathway Diagram
Diseases associated with Ngfr recombinant proteinOrgans/Tissues associated with Ngfr recombinant protein
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >111 publications with Ngfr and Nervous System Diseases
 Brain Diseases Antibodies  >51 publications with Ngfr and Brain Diseases
 Necrosis Antibodies  >36 publications with Ngfr and Necrosis
 Neurodegenerative Diseases Antibodies  >33 publications with Ngfr and Neurodegenerative Diseases
 Nerve Degeneration Antibodies  >30 publications with Ngfr and Nerve Degeneration
 Disease Models, Animal Antibodies  >22 publications with Ngfr and Disease Models, Animal
 Inflammation Antibodies  >21 publications with Ngfr and Inflammation
 Mental Disorders Antibodies  >19 publications with Ngfr and Mental Disorders
 Breast Neoplasms Antibodies  >14 publications with Ngfr and Breast Neoplasms
 Prostatic Neoplasms Antibodies  >14 publications with Ngfr and Prostatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >161 publications with Ngfr and Brain
 Dorsal Root Ganglion Antibodies  >18 publications with Ngfr and Dorsal Root Ganglion
 Eye Antibodies  >15 publications with Ngfr and Eye
 Adrenal Gland Antibodies  >8 publications with Ngfr and Adrenal Gland
 Inner Ear Antibodies  >6 publications with Ngfr and Inner Ear
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